2026 William C. de Groat: Medicine Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Medicine	106	6586	6191	3497	3244	612	37765

Research.com Recognitions

2001 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

William C. de Groat is affiliated with the University of Pittsburgh in the United States. Their research primarily intersects the fields of medicine and neuroscience, with a focus on urology and related subfields. The scientist's work encompasses cellular and molecular neuroscience, rheumatology, surgery, and the endocrine and autonomic systems. The main topics covered in their research include urinary bladder and prostate research, pelvic floor disorders treatments, urological disorders and treatments, neuroscience and neural engineering, pain mechanisms and treatments, muscle activation and electromyography studies, as well as the neuroscience of respiration and sleep.

Notable recent publications by William C. de Groat include the following:

Molecular Mechanisms of Neurogenic Lower Urinary Tract Dysfunction after Spinal Cord Injury, 2023, International Journal of Molecular Sciences
Restoring both continence and micturition after chronic spinal cord injury by pudendal neuromodulation, 2021, Experimental Neurology
LPS-mediated release of ATP from urothelial cells occurs by lysosomal exocytosis, 2020, Neurourology and Urodynamics
Effects of a new β3-adrenoceptor agonist, vibegron, on neurogenic bladder dysfunction and remodeling in mice with spinal cord injury, 2020, Neurourology and Urodynamics
Downstream projection of Barrington's nucleus to the spinal cord in mice, 2021, Journal of Neurophysiology

William C. de Groat frequently collaborates with several coauthors, including:

Changfeng Tai
Jonathan M. Beckel
Bing Shen
Jicheng Wang
Yihua Zhong

Publications are often found in the following venues:

Neurourology and Urodynamics
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
Neuromodulation Technology at the Neural Interface
Experimental Neurology
Journal of Neurophysiology

William C. de Groat was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2001.

Best Publications

The neural control of micturition

Clare J. Fowler;Derek Griffiths;William C. de Groat

1554
Citations
A neurologic basis for the overactive bladder

William C. de Groat

798
Citations
Muscarinic receptors: their distribution and function in body systems, and the implications for treating overactive bladder

Paul Abrams;Karl Erik Andersson;Jerry J. Buccafusco;Christopher Chapple

710
Citations
Vanilloid receptor expression suggests a sensory role for urinary bladder epithelial cells.

Lori A. Birder;Anthony J. Kanai;William C. de Groat;Susanna Kiss

636
Citations
Neural Control of the Lower Urinary Tract

William C. de Groat;Derek Griffiths;Naoki Yoshimura

563
Citations
Organization of the sacral parasympathetic reflex pathways to the urinary bladder and large intestine

William C. de Groat;Irving Nadelhaft;Irving Nadelhaft;Richard J. Milne;August M. Booth

553
Citations
The distribution of visceral primary afferents from the pelvic nerve to Lissauer's tract and the spinal gray matter and its relationship to the sacral parasympathetic nucleus

Charles Morgan;Charles Morgan;Irving Nadelhaft;Irving Nadelhaft;William C. de Groat;William C. de Groat

536
Citations
Increased Excitability of Afferent Neurons Innervating Rat Urinary Bladder after Chronic Bladder Inflammation

N Yoshimura;W C de Groat

497
Citations
Integrative control of the lower urinary tract: preclinical perspective

William C. de Groat

485
Citations
Mechanisms of disease: involvement of the urothelium in bladder dysfunction.

Lori A Birder;William C de Groat

459
Citations
Identification of a neuronal nitric oxide synthase in isolated cardiac mitochondria using electrochemical detection

Anthony J. Kanai;Linda L. Pearce;Paula R. Clemens;Lori A. Birder

425
Citations
Effect of bladder outlet obstruction on micturition reflex pathways in the rat.

William D. Steers;William C. De Groat

372
Citations
INTRAVESICAL CAPSAICIN AND RESINIFERATOXIN THERAPY: SPICING UP THE WAYS TO TREAT THE OVERACTIVE BLADDER

Michael B. Chancellor;William C. de Groat

361
Citations
Adrenergic- and capsaicin-evoked nitric oxide release from urothelium and afferent nerves in urinary bladder

Lori A. Birder;Gerard Apodaca;William C. De Groat;Anthony J. Kanai

346
Citations
Urethral afferent nerve activity affects the micturition reflex; implication for the relationship between stress incontinence and detrusor instability.

Suk Young Jung;Matthew O. Fraser;Hideo Ozawa;Osamu Yokoyama

337
Citations
Afferent nerve regulation of bladder function in health and disease.

William C. de Groat;Naoki Yoshimura

334
Citations
Sympathetic inhibition of the urinary bladder and of pelvic ganglionic transmission in the cat

William C. de Groat;William R. Saum

330
Citations
Alterations in afferent pathways from the urinary bladder of the rat in response to partial urethral obstruction

William D. Steers;Jonathan Ciambotti;Barbara Etzel;Susan Erdman

330
Citations
The urothelium in overactive bladder: Passive bystander or active participant?

William C. de Groat

317
Citations
Developmental and injury induced plasticity in the micturition reflex pathway

William C de Groat;Isao Araki;Margaret A Vizzard;Mitsuharu Yoshiyama

296
Citations

Frequent Co-Authors

Naoki Yoshimura University of Pittsburgh

Michael B. Chancellor University of Pittsburgh

James R. Roppolo University of Pittsburgh

Johnny Huard The University of Texas Health Science Center at Houston

Joseph C. Glorioso University of Pittsburgh

David A. Vorp University of Pittsburgh

William F. Goins University of Pittsburgh

Leaf Huang University of North Carolina at Chapel Hill

Karl-Erik Andersson Lund University

Gerard Apodaca University of Pittsburgh

External Links

Personal website of William C. de Groat Google Scholar page

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