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Medicine

D-Index
113
Citations
47160
World Ranking
4956
National Ranking
488

Overview

Christopher R. Chapple is a researcher affiliated with the Royal Hallamshire Hospital in the United Kingdom. Their work spans extensively within the field of Medicine, focusing primarily on Urology and its related subfields. The subfields of study associated with their research include Rheumatology, Surgery, Epidemiology, and Pulmonary and Respiratory Medicine.

The scientist's research delves into various topics largely concerning urinary health and urological disorders. Notable topics covered include:

  • Urinary Bladder and Prostate Research
  • Pelvic floor disorders treatments
  • Urological Disorders and Treatments
  • Urinary Tract Infections Management
  • Urologic and reproductive health conditions
  • Urinary and Genital Oncology Studies
  • Prostate Cancer Diagnosis and Treatment

Christopher R. Chapple has contributed to multiple scholarly articles across leading publication venues, with frequent appearances in:

  • Neurourology and Urodynamics
  • European Urology
  • European Urology Focus
  • The Journal of Urology
  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature

Several recent papers illustrate the scope and collaboration in their work, including:

  • European Association of Urology Guidelines Office Rapid Reaction Group: An Organisation-wide Collaborative Effort to Adapt the European Association of Urology Guidelines Recommendations to the Coronavirus Disease 2019 Era (2020), published in European Urology
  • Prostate-specific Antigen Testing as Part of a Risk-Adapted Early Detection Strategy for Prostate Cancer: European Association of Urology Position and Recommendations for 2021 (2021), published in European Urology
  • Diagnostic Assessment of Lower Urinary Tract Symptoms in Men Considering Prostate Surgery: A Noninferiority Randomised Controlled Trial of Urodynamics in 26 Hospitals (2020), published in European Urology
  • A Systematic Review of Surgical interventions for the Treatment of Bladder Pain Syndrome/Interstitial Cystitis (2020), published in European Urology Focus
  • Efficacy and Safety of Mirabegron versus Placebo Add-On Therapy in Men with Overactive Bladder Symptoms Receiving Tamsulosin for Underlying Benign Prostatic Hyperplasia: A Randomized, Phase 4 Study (PLUS) (2020), published in The Journal of Urology

Their research collaborations include frequent co-authors such as Nadir I. Osman, Paul Abrams, Naşide Mangır, Marcus J. Drake, and Richard Inman, reflecting sustained partnerships in clinical and academic investigations.

Best Publications

  • The Effects of Antimuscarinic Treatments in Overactive Bladder: An Update of a Systematic Review and Meta-Analysis

    Christopher R. Chapple;Vik Khullar;Zahava Gabriel;Dominic Muston

  • The prevalence of lower urinary tract symptoms (LUTS) in the USA, the UK and Sweden: results from the Epidemiology of LUTS (EpiLUTS) study.

    Karin S. Coyne;Chris C. Sexton;Christine L. Thompson;Ian Milsom

  • Muscarinic receptors: their distribution and function in body systems, and the implications for treating overactive bladder

    Paul Abrams;Karl Erik Andersson;Jerry J. Buccafusco;Christopher Chapple

  • EAU guidelines on urinary incontinence

    J. W. Thüroff;P. Abrams;K. E. Andersson;Walter Artibani

  • A Shifted Paradigm for the Further Understanding, Evaluation, and Treatment of Lower Urinary Tract Symptoms in Men: Focus on the Bladder

    Christopher R. Chapple;Claus G. Roehrborn

  • Efficacy and safety of onabotulinumtoxinA for idiopathic overactive bladder: a double-blind, placebo controlled, randomized, dose ranging trial.

    Roger Dmochowski;Christopher Chapple;Victor W. Nitti;Michael Chancellor

  • OnabotulinumtoxinA 100 U Significantly Improves All Idiopathic Overactive Bladder Symptoms and Quality of Life in Patients with Overactive Bladder and Urinary Incontinence: A Randomised, Double-Blind, Placebo-Controlled Trial

    Christopher Chapple;Karl-Dietrich Sievert;Scott MacDiarmid;Vik Khullar

  • Randomized Double-blind, Active-controlled Phase 3 Study to Assess 12-Month Safety and Efficacy of Mirabegron, a β3-Adrenoceptor Agonist, in Overactive Bladder

    Christopher R. Chapple;Steven A. Kaplan;David Mitcheson;Jiri Klecka

  • A Comparison of the Efficacy and Tolerability of Solifenacin Succinate and Extended Release Tolterodine at Treating Overactive Bladder Syndrome: Results of the STAR Trial

    C.R. Chapple;R. Martinez-Garcia;L. Selvaggi;P. Toozs-Hobson

  • Updated Systematic Review and Meta-analysis of the Comparative Data on Colposuspensions, Pubovaginal Slings, and Midurethral Tapes in the Surgical Treatment of Female Stress Urinary Incontinence

    Giacomo Novara;Walter Artibani;Matthew D. Barber;Christopher R. Chapple

  • MUSCARINIC RECEPTOR ANTAGONISTS IN THE TREATMENT OF OVERACTIVE BLADDER

    Christopher R. Chapple

  • Detrusor Underactivity and the Underactive Bladder: A New Clinical Entity? A Review of Current Terminology, Definitions, Epidemiology, Aetiology, and Diagnosis

    Nadir I. Osman;Christopher R. Chapple;Paul Abrams;Roger Dmochowski

  • Urinary Incontinence and its Relationship to Mental Health and Health-Related Quality of Life in Men and Women in Sweden, the United Kingdom, and the United States

    Karin S. Coyne;Marion Kvasz;Andrea M. Ireland;Ian Milsom

  • Evaluation and Treatment of Lower Urinary Tract Symptoms in Older Men

    P. Abrams;C. Chapple;S. Khoury;Claus Roehrborn

  • The ICS–‘BPH’ Study: the psychometric validity and reliability of the ICSmale questionnaire

    J.L. Donovan;P. Abrams;T.J. Peters;H.E. Kay

  • Silodosin Therapy for Lower Urinary Tract Symptoms in Men with Suspected Benign Prostatic Hyperplasia: Results of an International, Randomized, Double-Blind, Placebo- and Active-Controlled Clinical Trial Performed in Europe

    Christopher R. Chapple;Francesco Montorsi;Teuvo L.J. Tammela;Manfred Wirth

  • The Effects of Antimuscarinic Treatments in Overactive Bladder: A Systematic Review and Meta-Analysis

    Christopher Chapple;Vik Khullar;Zahava Gabriel;Julie Ann Dooley

  • Clinical Efficacy, Safety, and Tolerability of Once-Daily Fesoterodine in Subjects with Overactive Bladder

    Christopher Chapple;Philip Van Kerrebroeck;Andrea Tubaro;Cornelia Haag-Molkenteller

  • Tamsulosin, the first prostate-selective alpha 1A-adrenoceptor antagonist. A meta-analysis of two randomized, placebo-controlled, multicentre studies in patients with benign prostatic obstruction (symptomatic BPH). European Tamsulosin Study Group.

    C. R. Chapple;J. J. Wyndaele;J. Nordling;F. Boeminghaus

  • Urothelium-derived inhibitory factor(s) influences on detrusor muscle contractility in vitro.

    M H Hawthorn;C R Chapple;M Cock;R Chess-Williams

Frequent Co-Authors

Sheila MacNeil
Sheila MacNeil University of Sheffield
Paul Abrams
Paul Abrams Southmead Hospital
Ian Milsom
Ian Milsom University of Gothenburg
Luke Vale
Luke Vale Newcastle University
Linda Cardozo
Linda Cardozo University of Cambridge
Alan J. Wein
Alan J. Wein University of Miami
Dirk De Ridder
Dirk De Ridder University of Otago
Karl-Erik Andersson
Karl-Erik Andersson Lund University
Roger R. Dmochowski
Roger R. Dmochowski Vanderbilt University Medical Center
Claus G. Roehrborn
Claus G. Roehrborn The University of Texas Southwestern Medical Center

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