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D-Index & Metrics

Biology and Biochemistry

D-Index
48
Citations
8194
World Ranking
18410
National Ranking
7517

Overview

Fotini Gounari is affiliated with the University of Chicago in the United States. Their research focuses primarily on immunology and microbiology, with additional contributions in medicine. The work spans several subfields including immunology, molecular biology, oncology, public health, environmental and occupational health, and nutrition and dietetics.

The scientist has published extensively on topics related to immune cell function and interaction, T-cell and B-cell immunology, immunotherapy and immune responses, DNA repair mechanisms, acute lymphoblastic leukemia research, reproductive system and pregnancy, and IL-33, ST2, and ILC pathways.

Frequent publication venues for their work include The Journal of Immunology with seven publications, Nature Immunology with four, Proceedings of the National Academy of Sciences, Circulation, and JCI Insight.

Among their recent papers are:

  • Wnt-β-catenin activation epigenetically reprograms Treg cells in inflammatory bowel disease and dysplastic progression (2021, Nature Immunology)
  • TCF-1 controls Treg cell functions that regulate inflammation, CD8+ T cell cytotoxicity and severity of colon cancer (2021, Nature Immunology)
  • TCF-1: a maverick in T cell development and function (2022, Nature Immunology)
  • DP1 Activation Reverses Age-Related Hypertension Via NEDD4L-Mediated T-Bet Degradation in T Cells (2020, Circulation)
  • Tcf-1 promotes genomic instability and T cell transformation in response to aberrant β-catenin activation (2022, Proceedings of the National Academy of Sciences)

Frequent co-authors in their publications include Khashayarsha Khazaie, Stephen Arnovitz, Akinola Olumide Emmanuel, Melissa Tracy, and Georgios Tousinas.

Best Publications

  • Mast cells are an essential hematopoietic component for polyp development

    Elias Gounaris;Susan E. Erdman;Clifford Restaino;Michael F. Gurish

  • Current status of interleukin-10 and regulatory T-cells in cancer.

    Kristen L. Dennis;Nichole R. Blatner;Fotini Gounari;Khashayarsha Khazaie

  • TCR-inducible PLZF transcription factor required for innate phenotype of a subset of γδ T cells with restricted TCR diversity

    Taras Kreslavsky;Adam K. Savage;Robin Hobbs;Fotini Gounari

  • Purification of a NF1-like DNA-binding protein from rat liver and cloning of the corresponding cDNA.

    G. Paonessa;F. Gounari;R. Frank;R. Cortese

  • Thymic selection revisited: how essential is it?

    Harald von Boehmer;Iannis Aifantis;Fotini Gounari;Orly Azogui

  • The significant role of mast cells in cancer

    Khashayarsha Khazaie;Nichole R. Blatner;Mohammad Wasim Khan;Fotini Gounari

  • Constitutive pre-TCR signaling promotes differentiation through Ca2+ mobilization and activation of NF-kappaB and NFAT.

    Iannis Aifantis;Fotini Gounari;Luca Scorrano;Christine Borowski

  • Efficient thymic immigration of B220+ lymphoid-restricted bone marrow cells with T precursor potential.

    Colin H Martin;Iannis Aifantis;Iannis Aifantis;M Lucila Scimone;Ulrich H von Andrian

  • T-cell factor 1 is a gatekeeper for T-cell specification in response to Notch signaling

    Kristine Germar;Marei Dose;Tassos Konstantinou;Jiangwen Zhang

  • Expression of RORγt Marks a Pathogenic Regulatory T Cell Subset in Human Colon Cancer

    Nichole R. Blatner;Mary F. Mulcahy;Kristen L. Dennis;Denise Scholtens

  • Somatic activation of |[beta]|-catenin bypasses pre-TCR signaling and TCR selection in thymocyte development

    Fotini Gounari;Iannis Aifantis;Khashayarsha Khazaie;Sonja Hoeflinger

  • T-Regulatory Cells Shift from a Protective Anti-Inflammatory to a Cancer-Promoting Proinflammatory Phenotype in Polyposis

    Elias Gounaris;Nichole R. Blatner;Kristen Dennis;Fay Magnusson

  • Harnessing of the nucleosome-remodeling-deacetylase complex controls lymphocyte development and prevents leukemogenesis.

    Jiangwen Zhang;Audrey F Jackson;Taku Naito;Marei Dose

  • β-Catenin stabilization stalls the transition from Double-Positive to Single Positive stage and predisposes thymocytes to malignant transformation

    Zhuyan Guo;Marei Dose;Damian Kovalovsky;Rui Chang

  • The TLX1 oncogene drives aneuploidy in T cell transformation.

    Kim De Keersmaecker;Pedro Jose Real;Giusy Della Gatta;Teresa Palomero

  • Amino-terminal domain of NF1 binds to DNA as a dimer and activates adenovirus DNA replication.

    F. Gounari;R. De Francesco;J. Schmitt;P. C. Van Der Vliet

  • Abating colon cancer polyposis by Lactobacillus acidophilus deficient in lipoteichoic acid

    Khashayarsha Khazaie;Mojgan Zadeh;Mojgan Zadeh;Mohammad W. Khan;Praveen Bere

  • Activation of β-catenin signaling in differentiated mammary secretory cells induces transdifferentiation into epidermis and squamous metaplasias

    Keiko Miyoshi;Keiko Miyoshi;Jonathan M. Shillingford;Fabienne Le Provost;Fotini Gounari

  • Loss of adenomatous polyposis coli gene function disrupts thymic development

    Fotini Gounari;Rui Chang;Janet Cowan;Zhuyan Guo

  • β-Catenin Promotes Colitis and Colon Cancer Through Imprinting of Proinflammatory Properties in T Cells

    Shilpa Keerthivasan;Katayoun Aghajani;Marei Dose;Luciana Molinero

Frequent Co-Authors

Harald von Boehmer
Harald von Boehmer Harvard University
Iannis Aifantis
Iannis Aifantis New York University
David J. Bentrem
David J. Bentrem Northwestern University
Katia Georgopoulos
Katia Georgopoulos Harvard University
Michelle A. Kelliher
Michelle A. Kelliher University of Massachusetts Chan Medical School
Adolfo A. Ferrando
Adolfo A. Ferrando Columbia University
Volker Schirrmacher
Volker Schirrmacher German Cancer Research Center
Peter D. Aplan
Peter D. Aplan National Institutes of Health
Michael F. Gurish
Michael F. Gurish Harvard Medical School
Andreas Krueger
Andreas Krueger Goethe University Frankfurt

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