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Katia Georgopoulos

Katia Georgopoulos

D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
18998
World Ranking
10589
National Ranking
4600

Overview

Katia Georgopoulos is affiliated with Harvard University in the United States. Their research primarily spans immunology, microbiology, medicine, and biochemistry, genetics, and molecular biology. Within these broader fields, Georgopoulos has focused on several subfields including immunology, molecular biology, genetics, oncology, and physiology.

The scientist's research topics include immune cell function and interaction, immunotherapy and immune responses, genomics and chromatin dynamics, T-cell and B-cell immunology, vitamin D research studies, chromosomal and genetic variations, and genomic variations and chromosomal abnormalities.

Georgopoulos has contributed to a number of recent scientific papers. Selected publications are:

  • "A hotspot mutation in transcription factor IKZF3 drives B cell neoplasia via transcriptional dysregulation" (2021, Cancer Cell)
  • "STAG2 regulates interferon signaling in melanoma via enhancer loop reprogramming" (2022, Nature Communications)
  • "Lineage-specific 3D genome organization is assembled at multiple scales by IKAROS" (2023, Cell)
  • "Transcription factor Ikzf1 associates with Foxp3 to repress gene expression in Treg cells and limit autoimmunity and anti-tumor immunity" (2024, Immunity)
  • "Activated interleukin-7 receptor signaling drives B-cell acute lymphoblastic leukemia in mice" (2021, Leukemia)

Georgopoulos has collaborated frequently with other scientists such as Yeguang Hu, Daniela Salgado Figueroa, Ferhat Ay, Margaret Veselits, and Sourya Bhattacharyya. These collaborations contribute to a multidisciplinary approach across molecular biology, immunology, and oncology.

Their work is often published in prominent scientific venues including bioRxiv (Cold Spring Harbor Laboratory), Nature Immunology, eLife, Zenodo (CERN European Organization for Nuclear Research), and Cell.

Best Publications

  • c-Jun dimerizes with itself and with c-Fos, forming complexes of different DNA binding affinities.

    Thanos D. Halazonetis;Katia Georgopoulos;Michael E. Greenberg;Philip Leder

  • The Ikaros gene is required for the development of all lymphoid lineages.

    Katia Georgopoulos;Michael Bigby;Jin-Hong Wang;Arpad Molnar

  • Selective Defects in the Development of the Fetal and Adult Lymphoid System in Mice with an Ikaros Null Mutation

    Jin-Hong Wang;Aliki Nichogiannopoulou;Li Wu;Lei Sun

  • A dominant mutation in the Ikaros gene leads to rapid development of leukemia and lymphoma

    Susan Winandy;Paul Wu;Katia Georgopoulos

  • Ikaros DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes

    John Kim;Saïd Sif;Beverly Jones;Audrey Jackson

  • The Ikaros gene encodes a family of functionally diverse zinc finger DNA-binding proteins.

    A Molnár;K Georgopoulos

  • Ikaros, an early lymphoid-specific transcription factor and a putative mediator for T cell commitment

    Katia Georgopoulos;David D. Moore;Bruce Derfler

  • Zinc finger-mediated protein interactions modulate Ikaros activity, a molecular control of lymphocyte development.

    L Sun;A Liu;K Georgopoulos

  • Aiolos, a lymphoid restricted transcription factor that interacts with Ikaros to regulate lymphocyte differentiation

    Bruce Morgan;Lei Sun;Nicole Avitahl;Konstantinos Andrikopoulos

  • The Follicular versus Marginal Zone B Lymphocyte Cell Fate Decision Is Regulated by Aiolos, Btk, and CD21

    Annaiah Cariappa;Mei Tang;Chuenlei Parng;Eugene Nebelitskiy

  • Repression by Ikaros and Aiolos is mediated through histone deacetylase complexes.

    Joseph Koipally;Anja Renold;John Kim;Katia Georgopoulos

  • Haematopoietic cell-fate decisions, chromatin regulation and ikaros.

    Katia Georgopoulos

  • Early hematopoietic lineage restrictions directed by Ikaros.

    Toshimi Yoshida;Samuel Yao-Ming Ng;Juan Carlos Zuniga-Pflucker;Katia Georgopoulos

  • Aiolos regulates B cell activation and maturation to effector state

    Jin-Hong Wang;Nicole Avitahl;Annaiah Cariappa;Christof Friedrich

  • THE ROLE OF THE IKAROS GENE IN LYMPHOCYTE DEVELOPMENT AND HOMEOSTASIS

    Katia Georgopoulos;Susan Winandy;Nicole Avitahl

  • The Chromatin Remodeler Mi-2β Is Required for CD4 Expression and T Cell Development

    Christine J Williams;Taku Naito;Pablo Gómez-del Arco;John R Seavitt

  • Helios, a novel dimerization partner of Ikaros expressed in the earliest hematopoietic progenitors

    Clair M. Kelley;Tohru Ikeda;Joseph Koipally;Nicole Avitahl

  • Defects in Hemopoietic Stem Cell Activity in Ikaros Mutant Mice

    Aliki Nichogiannopoulou;Maryanne Trevisan;Steve Neben;Christoph Friedrich

  • Aiolos promotes TH17 differentiation by directly silencing Il2 expression

    Francisco J Quintana;Hulin Jin;Evan J Burns;Meghan Nadeau

  • Cell-Autonomous Defects in Dendritic Cell Populations of Ikaros Mutant Mice Point to a Developmental Relationship with the Lymphoid Lineage

    Li Wu;Aliki Nichogiannopoulou;Ken Shortman;Katia Georgopoulos

Frequent Co-Authors

Bruce A. Morgan
Bruce A. Morgan Saarland University
Cox Terhorst
Cox Terhorst Beth Israel Deaconess Medical Center
Hans Clevers
Hans Clevers Hubrecht Institute for Developmental Biology and Stem Cell Research
Li Wu
Li Wu Tsinghua University
Fotini Gounari
Fotini Gounari University of Chicago
Guido Ferlazzo
Guido Ferlazzo University of Messina
Dimitris Kioussis
Dimitris Kioussis Medical Research Council
Michael E. Talkowski
Michael E. Talkowski Harvard University
Marcy E. MacDonald
Marcy E. MacDonald Harvard University
James F. Gusella
James F. Gusella Harvard University

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