Michelle A. Kelliher

Overview

Best Publications

• The Death Domain Kinase RIP Mediates the TNF-Induced NF-κB Signal

  Michelle A Kelliher;Stefan Grimm;Yasumasa Ishida;Frank Kuo

  1357
  Citations

• RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activation.

  Etienne Meylan;Kim Burns;Kay Hofmann;Vincent Blancheteau

  1114
  Citations

• Pathogen blockade of TAK1 triggers caspase-8-dependent cleavage of gasdermin D and cell death.

  Pontus Orning;Pontus Orning;Dan Weng;Dan Weng;Kristian Starheim;Kristian Starheim;Dmitry Ratner

  975
  Citations

• Induction of a chronic myelogenous leukemia-like syndrome in mice with v-abl and BCR/ABL

  Michelle A. Kelliher;Jami McLaughlin;Owen N. Witte;Naomi Rosenberg

  672
  Citations

• RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer

  Andrew L Wolfe;Kamini Singh;Yi Zhong;Philipp Drewe

  629
  Citations

• The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1: TRAF2 recruits IKK to TNF-R1 while RIP mediates IKK activation.

  Anne Devin;Amy Cook;Yong Lin;Yolanda Rodriguez

  613
  Citations

• RIPK1 Blocks Early Postnatal Lethality Mediated by Caspase-8 and RIPK3

  Christopher P. Dillon;Ricardo Weinlich;Diego A. Rodriguez;James G. Cripps

  555
  Citations

• RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis

  Marius Dannappel;Katerina Vlantis;Snehlata Kumari;Apostolos Polykratis

  530
  Citations

• RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS.

  Yasushi Ito;Dimitry Ofengeim;Ayaz Najafov;Sudeshna Das

  530
  Citations

• Rip1 mediates the Trif-dependent toll-like receptor 3- and 4-induced NF-{kappa}B activation but does not contribute to interferon regulatory factor 3 activation.

  Nicole Cusson-Hermance;Smriti Khurana;Thomas H. Lee;Katherine A. Fitzgerald

  475
  Citations

• An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia.

  Birgit Knoechel;Justine E Roderick;Kaylyn E Williamson;Jiang Zhu

  408
  Citations

• BET Bromodomain Proteins Function as Master Transcription Elongation Factors Independent of CDK9 Recruitment.

  Georg E. Winter;Georg E. Winter;Andreas Mayer;Dennis L. Buckley;Michael A. Erb

  405
  Citations

• Core Transcriptional Regulatory Circuit Controlled by the TAL1 Complex in Human T Cell Acute Lymphoblastic Leukemia

  Takaomi Sanda;Lee N. Lawton;M. Inmaculada Barrasa;Zi Peng Fan

  363
  Citations

• Tal-1 induces T cell acute lymphoblastic leukemia accelerated by casein kinase IIalpha.

  M A Kelliher;D C Seldin;P Leder

  348
  Citations

• Notch1 contributes to mouse T-cell leukemia by directly inducing the expression of c-myc

  Vishva Mitra Sharma;Jennifer Ann Calvo;Kyle M. Draheim;Leslie A. Cunningham

  341
  Citations

• NOD2, RIP2 and IRF5 play a critical role in the type I interferon response to Mycobacterium tuberculosis.

  Amit K. Pandey;Yibin Yang;Zhaozhao Jiang;Sarah Merritt Fortune

  339
  Citations

• Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death

  Dan Weng;Robyn Lynn Marty-Roix;Sandhya Ganesan;Megan K. Proulx

  330
  Citations

• The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice

  Elizabeth C. Townsend;Mark A. Murakami;Alexandra Christodoulou;Amanda L. Christie

  328
  Citations

• RIPK1 mediates a disease-associated microglial response in Alzheimer’s disease

  Dimitry Ofengeim;Sonia Mazzitelli;Yasushi Ito;Judy Park DeWitt

  317
  Citations

• The kinase activity of Rip1 is not required for tumor necrosis factor-alpha-induced IkappaB kinase or p38 MAP kinase activation or for the ubiquitination of Rip1 by Traf2.

  Thomas H. Lee;Jennifer Shank;Nicole Cusson;Michelle A. Kelliher

  312
  Citations