What is he best known for?
The fields of study he is best known for:
- Apoptosis
- Immune system
- Genetics
His main research concerns Cell biology, Apoptosis, Necroptosis, Programmed cell death and Caspase 8.
His Cell biology research is multidisciplinary, relying on both Fas ligand, CD28, Receptor, Cell cycle and CTLA-4.
His research in Necroptosis is mostly concerned with RIPK1.
The concepts of his RIPK1 study are interwoven with issues in Ripoptosome and Kinase activity.
The Programmed cell death study combines topics in areas such as Necrosis and Neuroscience.
His research on Caspase 8 concerns the broader Caspase.
His most cited work include:
- Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation (1523 citations)
- Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. (1421 citations)
- A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling. (729 citations)
What are the main themes of his work throughout his whole career to date?
Francis Ka-Ming Chan mostly deals with Cell biology, Necroptosis, Programmed cell death, Apoptosis and RIPK1.
His Cell biology research incorporates themes from Tumor necrosis factor alpha, Caspase, Caspase 8 and Receptor.
His research integrates issues of Cancer research, Kinase, Protein kinase A, Inflammation and Innate immune system in his study of Necroptosis.
His Programmed cell death study combines topics from a wide range of disciplines, such as Inflammasome, Proinflammatory cytokine, Immunology, Necrosis and Neuroscience.
His studies in RIPK1 integrate themes in fields like FADD and Phosphorylation, Kinase activity.
The study incorporates disciplines such as Cell and Biophysics in addition to Signal transduction.
He most often published in these fields:
- Cell biology (66.33%)
- Necroptosis (53.06%)
- Programmed cell death (47.96%)
What were the highlights of his more recent work (between 2017-2021)?
- Necroptosis (53.06%)
- Cell biology (66.33%)
- Programmed cell death (47.96%)
In recent papers he was focusing on the following fields of study:
His primary areas of investigation include Necroptosis, Cell biology, Programmed cell death, RIPK1 and Phosphorylation.
His Necroptosis research includes themes of Virus, Viral replication, Macrophage and Kinase.
His research investigates the connection with Kinase and areas like Interferon which intersect with concerns in Receptor.
His research in the fields of Cell signaling overlaps with other disciplines such as Loss function.
His work on Intrinsic apoptosis, Immunogenic cell death and Pyroptosis as part of general Programmed cell death study is frequently linked to Biological pathway, therefore connecting diverse disciplines of science.
His work is dedicated to discovering how RIPK1, Protein kinase A are connected with Intracellular pH and Microbiology and other disciplines.
Between 2017 and 2021, his most popular works were:
- Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. (1421 citations)
- Necroptosis in anti-viral inflammation. (48 citations)
- Inflammasome, Inflammation, and Tissue Homeostasis. (37 citations)
In his most recent research, the most cited papers focused on:
- Immune system
- Apoptosis
- Genetics
His primary scientific interests are in Necroptosis, Macrophage, Inflammation, Programmed cell death and Cell biology.
His Necroptosis research is classified as research in Apoptosis.
His work carried out in the field of Macrophage brings together such families of science as Immunology, Immunopathology, Disease and Intracellular.
His Caspase 1 study, which is part of a larger body of work in Inflammation, is frequently linked to Intestinal epithelium, bridging the gap between disciplines.
His study in the field of RIPK1 and Caspase 8 also crosses realms of Leishmania infantum.
His Cell biology study integrates concerns from other disciplines, such as Wound healing and T cell, Immune system, Host Defense Mechanism.
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