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Jürgen Schmidt

Jürgen Schmidt

D-Index & Metrics

Chemistry

D-Index
54
Citations
8910
World Ranking
12780
National Ranking
942

Overview

Jürgen Schmidt is affiliated with the Leibniz Association in Germany and has contributed extensively to multiple scientific fields, particularly medicine and materials science. Their research spans various subfields including materials chemistry, infectious diseases, astronomy and astrophysics, molecular biology, and computational theory and mathematics.

The primary topics of Schmidt's work encompass crystallization and solubility studies, X-ray diffraction in crystallography, SARS-CoV-2 and COVID-19 research, computational drug discovery methods, astro and planetary science, protein structure and dynamics, and planetary science and exploration.

Some notable recent papers authored or coauthored by Schmidt include:

  • High-Throughput Virtual Screening and Validation of a SARS-CoV-2 Main Protease Noncovalent Inhibitor (2021, Journal of Chemical Information and Modeling)
  • Potent and Selective Covalent Inhibition of the Papain-like Protease from SARS-CoV-2 (2023, Nature Communications)
  • Engineering Catalysts for Selective Ester Hydrogenation (2020, Organic Process Research & Development)
  • Hepatitis C Virus NS3/4A Inhibitors and Other Drug-like Compounds as Covalent Binders of SARS-CoV-2 Main Protease (2022, Scientific Reports)
  • High Throughput Virtual Screening and Validation of a SARS-CoV-2 Main Protease Non-Covalent Inhibitor (2021, bioRxiv (Cold Spring Harbor Laboratory))

Frequent coauthors in Schmidt's research include:

  • Robert F. Williams
  • Yury Minko
  • Brooke N. Livesay
  • Brennan S. Billow
  • Aaron M. Tondreau

Schmidt's work is often published in the following venues:

  • The Cambridge Structural Database
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Philosophical Transactions of the Royal Society A Mathematical Physical and Engineering Sciences
  • Research Square (Research Square)
  • Peptides

Overall, Schmidt's research portfolio reflects an interdisciplinary approach bridging chemistry, biology, and computational sciences. Their contributions have involved studies of molecular structures and dynamics, particularly in relation to viral proteases involved in SARS-CoV-2, as well as broader materials chemistry and astro/planetary science topics.

Best Publications

  • Indole alkaloid biosynthesis in Catharanthus roseus: new enzyme activities and identification of cytochrome P450 CYP72A1 as secologanin synthase.

    Stefan Irmler;Gudrun Schröder;Benoit St‐Pierre;Nicholas P. Crouch

  • FACKEL is a sterol C-14 reductase required for organized cell division and expansion in Arabidopsis embryogenesis

    Kathrin Schrick;Ulrike Mayer;Andrea Horrichs;Christine Kuhnt

  • Profiling of Arabidopsis Secondary Metabolites by Capillary Liquid Chromatography Coupled to Electrospray Ionization Quadrupole Time-of-Flight Mass Spectrometry

    Edda von Roepenack-Lahaye;Thomas Degenkolb;Michael Zerjeski;Mathias Franz

  • New pathway to polyketides in plants

    Stefan Eckermann;Gudrun Schröder;Jürgen Schmidt;Dieter Strack

  • (R, S)- RETICULINE 7 O-METHYLTRANSFERASE AND (R, S)- NORCOCLAURINE 6-O-METHYLTRANSFERASE OF PAPAVER SOMNIFERUM - CDNA CLONING AND CHARACTERIZATION OF METHYL TRANSFER ENZYMES OF ALKALOID BIOSYNTHESIS IN OPIUM POPPY

    Anan Ounaroon;Gabriele Decker;Jürgen Schmidt;Friedrich Lottspeich

  • Light-induced cytochrome P450-dependent enzyme in indole alkaloid biosynthesis: tabersonine 16-hydroxylase.

    Gudrun Schröder;Elke Unterbusch;Melanie Kaltenbach;Jürgen Schmidt

  • Arbuscular mycorrhizal fungus-induced changes in the accumulation of secondary compounds in barley roots

    Heinrich Peipp;Walter Maier;Jürgen Schmidt;Victor Wray

  • Interactions between sterol biosynthesis genes in embryonic development of Arabidopsis

    Kathrin Schrick;Ulrike Mayer;Gottfried Martin;Catherine Bellini

  • Betalains of Celosia argentea.

    Willibald Schliemann;Yizhong Cai;Thomas Degenkolb;Jürgen Schmidt

  • Phytochelatins and heavy metal tolerance

    Ines Leopold;Detlef Günther;Jürgen Schmidt;Dieter Neumann

  • Comparative transcript and alkaloid profiling in Papaver species identifies a short chain dehydrogenase/reductase involved in morphine biosynthesis

    Jörg Ziegler;Susan Voigtländer;Jürgen Schmidt;Robert Kramell

  • A novel Mg2+-dependent O-methyltransferase in the phenylpropanoid metabolism of Mesembryanthemum crystallinum

    Mwafaq Ibdah;Xing-Hai Zhang;Jürgen Schmidt;Thomas Vogt

  • Endogenous formation of morphine in human cells

    Chotima Poeaknapo;Jürgen Schmidt;Matthias Brandsch;Birgit Dräger

  • Functional Analysis of the Final Steps of the 1-Deoxy-d-xylulose 5-phosphate (DXP) Pathway to Isoprenoids in Plants Using Virus-Induced Gene Silencing

    Jonathan E. Page;Gerd Hause;Maja Raschke;Wenyun Gao

  • Light-induced betacyanin and flavonol accumulation in bladder cells of Mesembryanthemum crystallinum.

    Thomas Vogt;Mwafaq Ibdah;Jürgen Schmidt;Victor Wray

  • A Stilbene Synthase Gene (SbSTS1) Is Involved in Host and Nonhost Defense Responses in Sorghum

    Christine K.Y. Yu;Karin Springob;Jürgen Schmidt;Ralph L. Nicholson

  • Formation of a complex pattern of sinapate esters in Brassica napus seeds, catalyzed by enzymes of a serine carboxypeptidase-like acyltransferase family?

    Alfred Baumert;Carsten Milkowski;Jürgen Schmidt;Manfred Nimtz

  • Occurrence and localization of apocarotenoids in arbuscular mycorrhizal plant roots.

    Thomas Fester;Bettina Hause;Diana Schmidt;Kristine Halfmann

  • Plant Polyketide Synthases: A Chalcone Synthase-Type Enzyme Which Performs a Condensation Reaction with Methylmalonyl-CoA in the Biosynthesis of C-Methylated Chalcones†,‡

    Joachim Schröder;Sigrid Raiber;Thorsten Berger;Axel Schmidt

  • Stilbenecarboxylate biosynthesis: a new function in the family of chalcone synthase-related proteins.

    Christian Eckermann;Gudrun Schröder;Stefan Eckermann;Dieter Strack

  • Evolution of morphine biosynthesis in opium poppy

    Jörg Ziegler;Peter J Facchini;René Geissler;Jürgen Schmidt

  • Metabolite profiling and fingerprinting of commercial cultivars of Humulus lupulus L. (hop): a comparison of MS and NMR methods in metabolomics

    Mohamed A. Farag;Mohamed A. Farag;Andrea Porzel;Jürgen Schmidt;Ludger A. Wessjohann

  • Poppy alkaloid profiling by electrospray tandem mass spectrometry and electrospray FT-ICR mass spectrometry after [ring-13C6]-tyramine feeding.

    Jürgen Schmidt;Chotima Boettcher;Chotima Boettcher;Christine Kuhnt;Toni M. Kutchan;Toni M. Kutchan

Frequent Co-Authors

Andrea Porzel
Andrea Porzel Leibniz Institute of Plant Biochemistry
Ludger A. Wessjohann
Ludger A. Wessjohann Leibniz Association
Dieter Strack
Dieter Strack Leibniz Association
Victor Wray
Victor Wray Heinrich Heine University Düsseldorf
Toni M. Kutchan
Toni M. Kutchan Donald Danforth Plant Science Center
Manfred Nimtz
Manfred Nimtz Helmholtz Centre for Infection Research
Lutz Heide
Lutz Heide University of Tübingen
Joachim Schröder
Joachim Schröder University of Freiburg
Shu-Ming Li
Shu-Ming Li Philipp University of Marburg
Otto Miersch
Otto Miersch Palacký University, Olomouc

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