Akitsugu Yamamoto

Research.com Recognitions

• 2026 - Research.com Biology and Biochemistry in Japan Leader Award
• 2025 - Research.com Biology and Biochemistry in Japan Leader Award
• 2023 - Research.com Biology and Biochemistry in Japan Leader Award

Overview

Best Publications

• Guidelines for the use and interpretation of assays for monitoring autophagy

  Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  8665
  Citations

• LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

  Yukiko Kabeya;Noboru Mizushima;Noboru Mizushima;Takashi Ueno;Akitsugu Yamamoto

  7923
  Citations

• Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

  Taichi Hara;Kenji Nakamura;Makoto Matsui;Makoto Matsui;Makoto Matsui;Akitsugu Yamamoto

  4436
  Citations

• The role of autophagy during the early neonatal starvation period

  Akiko Kuma;Masahiko Hatano;Makoto Matsui;Makoto Matsui;Akitsugu Yamamoto

  3485
  Citations

• In Vivo Analysis of Autophagy in Response to Nutrient Starvation Using Transgenic Mice Expressing a Fluorescent Autophagosome Marker

  Noboru Mizushima;Akitsugu Yamamoto;Makoto Matsui;Makoto Matsui;Tamotsu Yoshimori

  2833
  Citations

• Autophagosomes form at ER–mitochondria contact sites

  Maho Hamasaki;Nobumichi Furuta;Atsushi Matsuda;Atsushi Matsuda;Akiko Nezu

  1932
  Citations

• Dissection of Autophagosome Formation Using Apg5-Deficient Mouse Embryonic Stem Cells

  Noboru Mizushima;Noboru Mizushima;Akitsugu Yamamoto;Masahiko Hatano;Yoshinori Kobayashi;Yoshinori Kobayashi

  1785
  Citations

• LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation.

  Yukiko Kabeya;Noboru Mizushima;Noboru Mizushima;Akitsugu Yamamoto;Satsuki Oshitani-Okamoto

  1717
  Citations

• Bafilomycin A1 prevents maturation of autophagic vacuoles by inhibiting fusion between autophagosomes and lysosomes in rat hepatoma cell line, H-4-II-E cells

  Akitsugu Yamamoto;Yoshihiro Tagawa;Tamotsu Yoshimori;Yoshinori Moriyama

  1530
  Citations

• Bafilomycin A1, a specific inhibitor of vacuolar-type H(+)-ATPase, inhibits acidification and protein degradation in lysosomes of cultured cells.

  T Yoshimori;A Yamamoto;Y Moriyama;M Futai

  1481
  Citations

• Autophagy defends cells against invading group A Streptococcus.

  Ichiro Nakagawa;Atsuo Amano;Noboru Mizushima;Akitsugu Yamamoto

  1372
  Citations

• A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formation

  Mitsuko Hayashi-Nishino;Naonobu Fujita;Takeshi Noda;Akihito Yamaguchi

  1262
  Citations

• Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure

  Takafumi Oka;Shungo Hikoso;Osamu Yamaguchi;Manabu Taneike;Manabu Taneike

  1193
  Citations

• Subcellular Localization of Toll-Like Receptor 3 in Human Dendritic Cells

  Misako Matsumoto;Kenji Funami;Masako Tanabe;Hiroyuki Oshiumi

  996
  Citations

• Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate

  Noboru Mizushima;Noboru Mizushima;Akiko Kuma;Akiko Kuma;Yoshinori Kobayashi;Yoshinori Kobayashi;Akitsugu Yamamoto

  947
  Citations

• Autophagy Is Essential for Preimplantation Development of Mouse Embryos

  Satoshi Tsukamoto;Akiko Kuma;Mirei Murakami;Chieko Kishi

  759
  Citations

• An Atg4B Mutant Hampers the Lipidation of LC3 Paralogues and Causes Defects in Autophagosome Closure

  Naonobu Fujita;Mitsuko Hayashi-Nishino;Hiromi Fukumoto;Hiroko Omori

  569
  Citations

• Pivotal role of the cell death factor BNIP3 in ceramide-induced autophagic cell death in malignant glioma cells.

  Shigeru Daido;Takao Kanzawa;Akitsugu Yamamoto;Hayato Takeuchi

  563
  Citations

• Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophages

  George B. Kyei;Christina Dinkins;Alexander S Davis;Esteban Roberts

  559
  Citations

• Autophagy sequesters damaged lysosomes to control lysosomal biogenesis and kidney injury

  Ikuko Maejima;Atsushi Takahashi;Hiroko Omori;Tomonori Kimura

  548
  Citations