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Immunology

D-Index
51
Citations
10609
World Ranking
4138
National Ranking
1888

Overview

Vincent K. Tuohy is affiliated with the Cleveland Clinic Lerner College of Medicine in the United States. Their research primarily spans the fields of Immunology and Microbiology, Medicine, and Biochemistry, Genetics and Molecular Biology. The subfields of their work include Immunology, Oncology, Reproductive Medicine, Genetics, and Biotechnology.

The scientist's research focuses on several core topics, including:

  • Immunotherapy and Immune Responses
  • Ovarian cancer diagnosis and treatment
  • Cancer Immunotherapy and Biomarkers
  • Reproductive System and Pregnancy
  • Toxin Mechanisms and Immunotoxins
  • Cancer Research and Treatments
  • Cancer Genomics and Diagnostics

Notable recent papers authored or coauthored by Vincent K. Tuohy include:

  • Immunotherapy in breast cancer: an overview of current strategies and perspectives, 2023, npj Breast Cancer
  • Immunotherapy of ovarian cancer with a monoclonal antibody specific for the extracellular domain of anti-Müllerian hormone receptor II, 2020, Oncotarget
  • Phase I trial of an alpha-lactalbumin vaccine in patients with moderate- to high-risk operable triple-negative breast cancer (TNBC), 2022, Journal of Clinical Oncology
  • Primary immunoprevention of adult onset cancers by vaccinating against retired tissue-specific self-proteins, 2020, Seminars in Immunology
  • Formulation of an ovarian cancer vaccine with the squalene-based AddaVax adjuvant inhibits the growth of murine epithelial ovarian carcinomas, 2022, Clinical and Experimental Vaccine Research

Frequent coauthors contributing to the scientist's publications include:

  • Justin M. Johnson
  • Suparna Mazumder
  • Valerie Swank
  • G. Thomas Budd
  • Halle C. F. Moore

The primary venues where Vincent K. Tuohy's work has been published include:

  • Oncotarget
  • Cancer Research
  • npj Breast Cancer
  • Journal of Clinical Oncology
  • Seminars in Immunology

Best Publications

  • The adaptor Act1 is required for interleukin 17–dependent signaling associated with autoimmune and inflammatory disease

    Youcun Qian;Caini Liu;Justin Hartupee;Cengiz Zubeyir Altuntas

  • Astrocyte expression of mRNA encoding cytokines IP-10 and JE/MCP-1 in experimental autoimmune encephalomyelitis.

    R M Ransohoff;T A Hamilton;M Tani;M H Stoler

  • Shaping of the autoreactive T-cell repertoire by a splice variant of self protein expressed in thymic epithelial cells.

    Ludger Klein;Ludger Klein;Matthias Klugmann;Klaus Armin Nave;Vincent K. Tuohy

  • Synchronous synthesis of alpha- and beta-chemokines by cells of diverse lineage in the central nervous system of mice with relapses of chronic experimental autoimmune encephalomyelitis.

    Andrzej R. Glabinski;Marie Tani;Robert M. Strieter;Vincent K Tuohy

  • Axon loss in the spinal cord determines permanent neurological disability in an animal model of multiple sclerosis.

    Jerome R. Wujek;Carl Bjartmar;Edward Richer;Richard M. Ransohoff

  • The Toll–Interleukin-1 Receptor Member SIGIRR Regulates Colonic Epithelial Homeostasis, Inflammation, and Tumorigenesis

    Hui Xiao;Muhammet Fatih Gulen;Muhammet Fatih Gulen;Jinzhong Qin;Jinzhong Qin;Jianhong Yao

  • A predictable sequential determinant spreading cascade invariably accompanies progression of experimental autoimmune encephalomyelitis: a basis for peptide-specific therapy after onset of clinical disease.

    Min Yu;Justin M. Johnson;Vincent K Tuohy

  • Astrocyte-Restricted Ablation of Interleukin-17-Induced Act1-Mediated Signaling Ameliorates Autoimmune Encephalomyelitis

    Zizhen Kang;Cengiz Zubeyir Altuntas;Muhammet Fatih Gulen;Caini Liu

  • Immunotherapy in breast cancer: an overview of current strategies and perspectives

    Unknown

  • In vivo effects of interferon beta-1a on immunosuppressive cytokines in multiple sclerosis

    Richard A. Rudick;R. M. Ransohoff;J. C. Lee;R. Peppler

  • Normal and reactive NG2+ glial cells are distinct from resting and activated microglia

    Akiko Nishiyama;Min Yu;Judith A. Drazba;Vincent K. Tuohy

  • The receptor SIGIRR suppresses Th17 cell proliferation via inhibition of the interleukin-1 receptor pathway and mTOR kinase activation.

    Muhammet F. Gulen;Zizhen Kang;Katarzyna Bulek;Wan Youzhong

  • Treatment of experimental autoimmune encephalomyelitis with genetically modified memory T cells

    Peter M. Mathisen;Min Yu;Justin M. Johnson;Judith A. Drazba

  • The epitope spreading cascade during progression of experimental autoimmune encephalomyelitis and multiple sclerosis.

    Vincent K. Tuohy;Min Yu;Ling Yin;Julie A. Kawczak

  • Spontaneous Regression of Primary Autoreactivity during Chronic Progression of Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis

    Vincent K. Tuohy;Min Yu;Ling Yin;Julie A. Kawczak

  • Diversity and plasticity of self recognition during the development of multiple sclerosis.

    V K Tuohy;M Yu;B Weinstock-Guttman;R P Kinkel

  • Interferon-β inhibits progression of relapsing-remitting experimental autoimmune encephalomyelitis

    Min Yu;Akiko Nishiyama;Bruce D. Trapp;Vincent K. Tuohy

  • Central Nervous System Chemokine mRNA Accumulation Follows Initial Leukocyte Entry at the Onset of Acute Murine Experimental Autoimmune Encephalomyelitis

    A. R. Glabinski;M. Tani;Vincent K Tuohy;R. J. Tuthill

  • Class II-restricted T cell responses in Theiler's murine encephalomyelitis virus (TMEV)-induced demyelinating disease: III. Failure of neuroantigen-specific immune tolerance to affect the clinical course of demyelination☆

    Stephen D. Miller;Sheila J. Gerety;Mary K. Kennedy;Jeffrey D. Peterson

  • An autoimmune-mediated strategy for prophylactic breast cancer vaccination.

    Ritika Jaini;Pavani Kesaraju;Pavani Kesaraju;Justin M Johnson;Cengiz Z Altuntas;Cengiz Z Altuntas

  • In situ hybridization analysis of glial fibrillary acidic protein mRNA reveals evidence of biphasic astrocyte activation during acute experimental autoimmune encephalomyelitis.

    Marie Tani;Andrzej R. Glabinski;Vincent K Tuohy;Mark H. Stoler;Mark H. Stoler

Frequent Co-Authors

Richard M. Ransohoff
Richard M. Ransohoff Harvard University
Xiaoxia Li
Xiaoxia Li Cleveland Clinic Lerner College of Medicine
Mark H. Stoler
Mark H. Stoler University of Virginia
Akiko Nishiyama
Akiko Nishiyama University of Connecticut
Richard A. Rudick
Richard A. Rudick Biogen (United States)
Wendy B. Macklin
Wendy B. Macklin University of Colorado Anschutz Medical Campus
Daniel J. Cua
Daniel J. Cua Johnson & Johnson (United States)
Stephen A. Stohlman
Stephen A. Stohlman Cleveland Clinic
Thomas A. Hamilton
Thomas A. Hamilton Cleveland Clinic
Bruce A. Vallance
Bruce A. Vallance University of British Columbia

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