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D-Index & Metrics

Biology and Biochemistry

D-Index
47
Citations
7679
World Ranking
18729
National Ranking
33

Overview

Judit Ovádi is affiliated with the Hungarian Academy of Sciences in Hungary and has contributed extensively to the fields of Biochemistry, Genetics, and Molecular Biology as well as Medicine. Their research portfolio includes a strong focus on Molecular Biology, Neurology, and Cellular and Molecular Neuroscience, with additional work in Epidemiology and Physiology. The scientist's work also addresses topics such as Parkinson's Disease mechanisms and treatments, ubiquitin and proteasome pathways, protein degradation and inhibitors, histone deacetylase inhibitors research, autophagy in disease and therapy, genomics and chromatin dynamics, and nerve injury and regeneration.

Ovádi's publication record includes papers in several notable scientific journals, with multiple contributions to the journal Cells. Their recent papers include:

  • Challenges in Discovering Drugs That Target the Protein-Protein Interactions of Disordered Proteins (2022, International Journal of Molecular Sciences)
  • Microtubule-Associated Proteins with Regulatory Functions by Day and Pathological Potency at Night (2020, Cells)
  • HaloTag-Targeted Sirtuin-Rearranging Ligand (SirReal) for the Development of Proteolysis-Targeting Chimeras (PROTACs) against the Lysine Deacetylase Sirtuin 2 (Sirt2) (2020, ChemBioChem)
  • Co-Transmission of Alpha-Synuclein and TPPP/p25 Inhibits Their Proteolytic Degradation in Human Cell Models (2021, Frontiers in Molecular Biosciences)
  • Modulatory Role of TPPP3 in Microtubule Organization and Its Impact on Alpha-Synuclein Pathology (2022, Cells)

Frequent co-authors of Judit Ovádi include Judit Oláh, Attila Lehotzky, Tibor Szénási, Victor Norris, and Sándor Szunyogh. Collaborations with these researchers demonstrate consistent partnerships in advancing studies primarily related to molecular and cellular aspects of neurobiology and protein interactions.

Ovádi's research has been published across various international venues including:

  • Cells
  • International Journal of Molecular Sciences
  • ChemBioChem
  • Frontiers in Molecular Biosciences
  • npj Systems Biology and Applications

Best Publications

  • Physiological significance of metabolic channelling.

    Judit Ovádi

  • Selective Sirt2 inhibition by ligand-induced rearrangement of the active site.

    Tobias Rumpf;Matthias Schiedel;Berin Karaman;Claudia Roessler

  • Chemically Induced Degradation of Sirtuin 2 (Sirt2) by a Proteolysis Targeting Chimera (PROTAC) Based on Sirtuin Rearranging Ligands (SirReals)

    Matthias Schiedel;Daniel Herp;Sören Hammelmann;Sören Swyter

  • Macromolecular Compartmentation and Channeling

    Judit Ovádi;Paul A. Srere

  • Nuclear Translocation of the Tumor Marker Pyruvate Kinase M2 Induces Programmed Cell Death

    Attila Steták;Réka Veress;Judit Ovádi;Péter Csermely

  • On the origin of intracellular compartmentation and organized metabolic systems.

    Judit Ovádi;Valdur Saks;Valdur Saks

  • Natively unfolded tubulin polymerization promoting protein TPPP/p25 is a common marker of alpha-synucleinopathies

    Gabor G. Kovacs;Lajos Laszlo;Janos Kovacs;Poul Henning Jensen

  • Triosephosphate isomerase deficiency: new insights into an enigmatic disease

    Ferenc Orosz;Judit Oláh;Judit Ovádi

  • Interactions of Pathological Hallmark Proteins: TUBULIN POLYMERIZATION PROMOTING PROTEIN/p25, β-AMYLOID, AND α-SYNUCLEIN*

    Judit Oláh;Orsolya Vincze;Dezső Virók;Dóra Simon

  • Triosephosphate isomerase deficiency: facts and doubts.

    Ferenc Orosz;Judit Oláh;Judit Ovádi

  • Tubulin polymerization-promoting protein (TPPP/p25) is critical for oligodendrocyte differentiation.

    Attila Lehotzky;Pierre Lau;Natália Tökési;Naser Muja

  • Brain-Specific p25 Protein Binds to Tubulin and Microtubules and Induces Aberrant Microtubule Assemblies at Substoichiometric Concentrations †

    Emma Hlavanda;János Kovács;Judit Oláh;Ferenc Orosz

  • TPPP/p25 promotes tubulin assemblies and blocks mitotic spindle formation

    L. Tirián;E. Hlavanda;J. Oláh;I. Horváth

  • Enzyme-enzyme interactions and their metabolic role

    Paul A. Srere;Judit Ovadi

  • Kinetic Evidence for Interaction between Aldolase and d-Glyceraldehyde-3-Phosphate Dehydrogenase

    Judit Ovádi;Tamás Keleti

  • TPPP/p25 Promotes Tubulin Acetylation by Inhibiting Histone Deacetylase 6

    Natália Tokési;Attila Lehotzky;István Horváth;Bálint Szabó

  • Old pathway--new concept: control of glycolysis by metabolite-modulated dynamic enzyme associations.

    Judit Ovádi

  • Physico-chemical Evidence for the Interaction between Aldolase and Glyceraldehyde-3-phosphate Dehydrogenase

    Judit Ovádi;Tamás Keleti;Costantino Salerno;Paolo Fasella

  • Interaction of phosphofructokinase with tubulin and microtubules. Quantitative evaluation of the mutual effects.

    Attila Lehotzky;Marianna Telegdi;Károly Liliom;Judit Ovádi

  • Tubulin polymerization promoting proteins (TPPPs): members of a new family with distinct structures and functions.

    Orsolya Vincze;Natália Tökési;Judit Oláh;Emma Hlavanda

Frequent Co-Authors

Manfred Jung
Manfred Jung University of Freiburg
Marta Cascante
Marta Cascante University of Barcelona
Wolfgang Sippl
Wolfgang Sippl Martin Luther University Halle-Wittenberg
Gabor G. Kovacs
Gabor G. Kovacs University of Toronto
András Perczel
András Perczel Eötvös Loránd University
Katalin F. Medzihradszky
Katalin F. Medzihradszky University of California, San Francisco
Paul A. Srere
Paul A. Srere The University of Texas Southwestern Medical Center
Oliver Einsle
Oliver Einsle University of Freiburg
Herbert Budka
Herbert Budka Medical University of Vienna

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