Yoshinori Ohsumi

Research.com Recognitions

• 2026 - Research.com Biology and Biochemistry in Japan Leader Award
• 2026 - Research.com Chemistry in Japan Leader Award
• 2025 - Research.com Biology and Biochemistry in Japan Leader Award
• 2025 - Research.com Chemistry in Japan Leader Award
• 2023 - Research.com Biology and Biochemistry in Japan Leader Award
• 2022 - Research.com Biology and Biochemistry in Japan Leader Award
• 2022 - Research.com Chemistry in Japan Leader Award
• 2017 - Breakthrough Prize in Life Sciences for elucidating autophagy, the recycling system that cells use to generate nutrients from their own inessential or damaged components.
• 2017 - Fellow of the American Association for the Advancement of Science (AAAS)
• 2016 - Dr. Paul Janssen Award for Biomedical Research, Johnson & Johnson for his pioneering discoveries in the field of autophagy.
• 2016 - Nobel Prize for his discoveries of mechanisms for autophagy
• 2015 - Canada Gairdner International Award
• 2015 - Keio Medical Science Prize, Keio University, Tokyo, Japan
• 2012 - Kyoto Prize in Life sciences Outstanding Contribution to Elucidating the Molecular Mechanisms and Physiological Significance of Autophagy, a Cellular Adaptive System to Environment

Overview

Best Publications

• LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

  Yukiko Kabeya;Noboru Mizushima;Noboru Mizushima;Takashi Ueno;Akitsugu Yamamoto

  7923
  Citations

• The role of autophagy during the early neonatal starvation period

  Akiko Kuma;Masahiko Hatano;Makoto Matsui;Makoto Matsui;Akitsugu Yamamoto

  3485
  Citations

• The Role of Atg Proteins in Autophagosome Formation

  Noboru Mizushima;Tamotsu Yoshimori;Yoshinori Ohsumi

  3346
  Citations

• In Vivo Analysis of Autophagy in Response to Nutrient Starvation Using Transgenic Mice Expressing a Fluorescent Autophagosome Marker

  Noboru Mizushima;Akitsugu Yamamoto;Makoto Matsui;Makoto Matsui;Tamotsu Yoshimori

  2833
  Citations

• Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

  Xueping Qu;Jie Yu;Govind Bhagat;Norihiko Furuya

  2789
  Citations

• Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice

  Masaaki Komatsu;Satoshi Waguri;Takashi Ueno;Junichi Iwata

  2776
  Citations

• Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae.

  Miki Tsukada;Yoshinori Ohsumi

  2487
  Citations

• A ubiquitin-like system mediates protein lipidation

  Yoshinobu Ichimura;Takayoshi Kirisako;Takayoshi Kirisako;Toshifumi Takao;Yoshinori Satomi

  2430
  Citations

• A protein conjugation system essential for autophagy

  Noboru Mizushima;Takeshi Noda;Tamotsu Yoshimori;Yae Tanaka

  2074
  Citations

• Dynamics and diversity in autophagy mechanisms: lessons from yeast

  Hitoshi Nakatogawa;Kuninori Suzuki;Yoshiaki Kamada;Yoshinori Ohsumi

  2060
  Citations

• Molecular dissection of autophagy: two ubiquitin-like systems.

  Yoshinori Ohsumi

  1794
  Citations

• Dissection of Autophagosome Formation Using Apg5-Deficient Mouse Embryonic Stem Cells

  Noboru Mizushima;Noboru Mizushima;Akitsugu Yamamoto;Masahiko Hatano;Yoshinori Kobayashi;Yoshinori Kobayashi

  1785
  Citations

• LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation.

  Yukiko Kabeya;Noboru Mizushima;Noboru Mizushima;Akitsugu Yamamoto;Satsuki Oshitani-Okamoto

  1717
  Citations

• Atg8, a Ubiquitin-like Protein Required for Autophagosome Formation, Mediates Membrane Tethering and Hemifusion

  Hitoshi Nakatogawa;Yoshinobu Ichimura;Yoshinori Ohsumi

  1679
  Citations

• A Unified Nomenclature for Yeast Autophagy-Related Genes

  Daniel J. Klionsky;James M. Cregg;William A Dunn;Scott D. Emr

  1662
  Citations

• Autophagy in yeast demonstrated with proteinase-deficient mutants and conditions for its induction

  Kazuhiko Takeshige;Misuzu Baba;Shigeru Tsuboi;Takeshi Noda

  1598
  Citations

• Tor, a Phosphatidylinositol Kinase Homologue, Controls Autophagy in Yeast

  Takeshi Noda;Yoshinori Ohsumi

  1552
  Citations

• Tor-Mediated Induction of Autophagy via an Apg1 Protein Kinase Complex

  Yoshiaki Kamada;Tomoko Funakoshi;Takahiro Shintani;Kazuya Nagano

  1471
  Citations

• Historical landmarks of autophagy research

  Yoshinori Ohsumi

  1302
  Citations

• The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy.

  Takao Hanada;Nobuo N. Noda;Yoshinori Satomi;Yoshinobu Ichimura

  1297
  Citations

• Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae.

  Akio Kihara;Takeshi Noda;Naotada Ishihara;Yoshinori Ohsumi

  1226
  Citations