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Biology and Biochemistry

D-Index
53
Citations
7562
World Ranking
16380
National Ranking
1296

Overview

Simon J. Morley is affiliated with the University of Sussex in the United Kingdom. Their primary field of study is Medicine, with a focus on several subfields including Surgery, Neurology, Epidemiology, Oncology, and Radiology, Nuclear Medicine and Imaging.

The main topics of Simon J. Morley's research work cover a range of areas related to medical conditions and treatments, specifically:

  • Salivary Gland Tumors Diagnosis and Treatment
  • Facial Nerve Paralysis Treatment and Research
  • Meningioma and Schwannoma Management
  • Oral and Maxillofacial Pathology
  • Vestibular and Auditory Disorders
  • Head and Neck Anomalies
  • Anatomy and Medical Technology

Frequent collaborators of Simon J. Morley include:

  • Mark McGurk
  • Soudeh Chegini
  • Timothy Beale
  • Tim Beale
  • Susan Jawad

Publications by Simon J. Morley have appeared predominantly in several peer-reviewed venues. The most frequent publication venues are:

  • British Journal of Oral and Maxillofacial Surgery
  • European Journal of Surgical Oncology
  • Radiographics
  • Clinical Endocrinology
  • BDJ (British Dental Journal)

Notable recent papers co-authored by or associated with Simon J. Morley include:

  • High-Resolution Laryngeal US: Imaging Technique, Normal Anatomy, and Spectrum of Disease (2020), published in Radiographics
  • COVID-19-related thyroiditis: A novel disease entity? (2021), published in Clinical Endocrinology
  • The use of mixed reality in dentistry (2022), published in BDJ
  • Dis3L2 regulates cell proliferation and tissue growth through a conserved mechanism (2020), published in PLoS Genetics
  • Treating papillary and follicular thyroid cancer in children and young people: Single UK-center experience between 2003 and 2018 (2020), published in Journal of Pediatric Surgery

Best Publications

  • Rapamycin inhibition of the G1 to S transition is mediated by effects on cyclin D1 mRNA and protein stability

    Said Hashemolhosseini;Yoshikuni Nagamine;Simon J. Morley;Sylvane Desrivières

  • Translation initiation factor modifications and the regulation of protein synthesis in apoptotic cells

    M J Clemens;M Bushell;I W Jeffrey;V M Pain

  • The C-terminal domain of eukaryotic protein synthesis initiation factor (eIF) 4G is sufficient to support cap-independent translation in the absence of eIF4E.

    T. Ohlmann;M. Rau;V. M. Pain;S. J. Morley

  • Differential Stimulation of Phosphorylation of Initiation Factors eIF-4F, eIF-4B, eIF-3, and Ribosomal Protein S6 by Insulin and Phorbol Esters

    S J Morley;J A Traugh

  • eIF4G: translation's mystery factor begins to yield its secrets.

    Simon J Morley;Penelope S Curtis;Virginia M Pain

  • Activation of p70s6k is associated with phosphorylation of four clustered sites displaying Ser/Thr-Pro motifs.

    Stefano Ferrari;Willi Bannwarth;Simon J. Morley;Nicholas F. Totty

  • A Reevaluation of the Cap-binding Protein, eIF4E, as a Rate-limiting Factor for Initiation of Translation in Reticulocyte Lysate

    Michael Rau;Theophile Ohlmann;Simon J. Morley;Virginia M. Pain

  • Involvement of stress-activated protein kinase and p38/RK mitogen-activated protein kinase signaling pathways in the enhanced phosphorylation of initiation factor 4E in NIH 3T3 cells.

    Simon J. Morley;Linda McKendrick

  • Degradation of eukaryotic polypeptide chain initiation factor (eIF) 4G in response to induction of apoptosis in human lymphoma cell lines

    Michael J Clemens;Martin Bushell;Simon J Morley

  • Phorbol esters stimulate phosphorylation of eukaryotic initiation factors 3, 4B, and 4F.

    S J Morley;J A Traugh

  • Activity of the Hepatitis A Virus IRES Requires Association between the Cap-Binding Translation Initiation Factor (eIF4E) and eIF4G

    Iraj K. Ali;Linda McKendrick;Simon J. Morley;Richard J. Jackson

  • Paxillin associates with poly(A)-binding protein 1 at the dense endoplasmic reticulum and the leading edge of migrating cells.

    Alison J. Woods;Marnie S. Roberts;Jyoti Choudhary;Simon T. Barry

  • Phosphorylation of eukaryotic initiation factor (eIF) 4E is not required for de novo protein synthesis following recovery from hypertonic stress in human kidney cells.

    Simon J. Morley;Susanne Naegele

  • Initiation factor modifications in the preapoptotic phase.

    S J Morley;M J Coldwell;M J Clemens

  • Cleavage of polypeptide chain initiation factor eIF4GI during apoptosis in lymphoma cells: characterisation of an internal fragment generated by caspase-3-mediated cleavage

    M Bushell;D Poncet;W E Marissen;H Flotow

  • Disruption of the Interaction of Mammalian Protein Synthesis Eukaryotic Initiation Factor 4B with the Poly(A)-binding Protein by Caspase- and Viral Protease-mediated Cleavages

    Martin Bushell;Wendy Wood;Gillian Carpenter;Virginia M. Pain

  • Changes in integrity and association of eukaryotic protein synthesis initiation factors during apoptosis.

    Martin Bushell;Wendy Wood;Michael J. Clemens;Simon J. Morley

  • Proteolytic cleavage of initiation factor elF-4γ in the reticulocyte lysate inhibits translation of capped mRNAs but enhances that of uncapped mRNAs

    Theophile Ohimann;Michael Rau;Simon J. Morley;Virginia M. Pain

  • Phosphorylation of eukaryotic initiation factor 4E (eIF4E) at Ser209 is not required for protein synthesis in vitro and in vivo.

    Linda McKendrick;Simon J. Morley;Virginia M. Pain;Rosemary Jagus

  • Interaction of Eukaryotic Translation Initiation Factor 4G with the Nuclear Cap-Binding Complex Provides a Link between Nuclear and Cytoplasmic Functions of the m7 Guanosine Cap

    Linda McKendrick;Elizabeth Thompson;Joao Ferreira;Simon J. Morley

Frequent Co-Authors

Martin Bushell
Martin Bushell University of Glasgow
Michael J. Clemens
Michael J. Clemens University of Sussex
Stefano Ferrari
Stefano Ferrari Veneto Eye Bank Foundation
Jolinda A. Traugh
Jolinda A. Traugh University of California, Riverside
Cecília M. Arraiano
Cecília M. Arraiano Universidade Nova de Lisboa
George Thomas
George Thomas Oregon Health & Science University
Panagis Filippakopoulos
Panagis Filippakopoulos Structural Genomics Consortium
Daniel R. Gallie
Daniel R. Gallie University of California, Riverside
Helen Stewart
Helen Stewart Brighton and Sussex Medical School
Simon J. Coles
Simon J. Coles University of Southampton

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