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Martin Holcik

Martin Holcik

D-Index & Metrics

Molecular Biology

D-Index
54
Citations
12054
World Ranking
2316
National Ranking
74

Overview

Martin Holcik is affiliated with Carleton University in Canada and specializes in the field of Biochemistry, Genetics and Molecular Biology. Their research focuses primarily on molecular biology, with a notable presence in related subfields such as clinical psychology, clinical biochemistry, sociology and political science, and obstetrics and gynecology.

The scientist's work covers several main topics, including:

  • RNA modifications and cancer
  • RNA research and splicing
  • Mitochondrial function and pathology
  • Fungal and yeast genetics research
  • RNA and protein synthesis mechanisms
  • Metabolism and genetic disorders
  • Redox biology and oxidative stress

Recent papers authored or coauthored by Martin Holcik include:

  • "Diseases Associated with Defects in tRNA CCA Addition" (2020), published in International Journal of Molecular Sciences
  • "Identification of therapeutics that target eEF1A2 and upregulate utrophin A translation in dystrophic muscles" (2020), published in Nature Communications
  • "Lithium Chloride Sensitivity in Yeast and Regulation of Translation" (2020), published in International Journal of Molecular Sciences
  • "Sensitivity of yeast to lithium chloride connects the activity of YTA6 and YPR096C to translation of structured mRNAs" (2020), published in PLoS ONE
  • "Diverse roles of heterogeneous nuclear ribonucleoproteins in viral life cycle" (2022), published in Frontiers in Virology

Frequent coauthors include Maryam Hajikarimlou, Myron L. Smith, Bahram Samanfar, Ashkan Golshani, and Sarah Takallou, with multiple collaborations indicating sustained research partnerships.

Martin Holcik has frequently published in the following venues:

  • International Journal of Molecular Sciences (2 publications)
  • PLoS ONE (2 publications)
  • Genes (2 publications)
  • Nature Communications (1 publication)
  • Frontiers in Virology (1 publication)

Best Publications

  • Translational control in stress and apoptosis

    Martin Holcik;Nahum Sonenberg

  • XIAP: apoptotic brake and promising therapeutic target.

    Martin Holcik;Hilary Gibson;Robert G. Korneluk

  • Searching for IRES.

    Stephen D. Baird;Marcel Turcotte;Robert G. Korneluk;Martin Holcik

  • XIAP, the guardian angel

    Martin Holcik;Robert G. Korneluk

  • A new internal-ribosome-entry-site motif potentiates XIAP- mediated cytoprotection

    Martin Holcik;Charles Lefebvre;Chiaoli Yeh;Terry Chow

  • Translational upregulation of X-linked inhibitor of apoptosis (XIAP) increases resistance to radiation induced cell death.

    Martin Holcik;Chiaoli Yeh;Robert G Korneluk;Robert G Korneluk;Terry Chow

  • RNA-Binding Proteins HuR and PTB Promote the Translation of Hypoxia-Inducible Factor 1α

    Stefanie Galbán;Yuki Kuwano;Rudolf Pullmann;Jennifer L. Martindale

  • Perk-dependent translational regulation promotes tumor cell adaptation and angiogenesis in response to hypoxic stress

    Jaime D. Blais;Christina L. Addison;Robert Edge;Theresa Falls

  • An oxygen-regulated switch in the protein synthesis machinery

    James Uniacke;Chet E. Holterman;Gabriel Lachance;Aleksandra Franovic

  • Internal ribosome initiation of translation and the control of cell death

    Martin Holcik;Nahum Sonenberg;Robert G. Korneluk

  • Functional Characterization of the X-Linked Inhibitor of Apoptosis (XIAP) Internal Ribosome Entry Site Element: Role of La Autoantigen in XIAP Translation

    Martin Holcik;Robert G. Korneluk

  • Posttranscriptional regulation of collagen alpha1(I) mRNA in hepatic stellate cells.

    B Stefanovic;C Hellerbrand;M Holcik;M Briendl

  • Four highly stable eukaryotic mRNAs assemble 3′ untranslated region RNA–protein complexes sharing cis and trans components

    Martin Holcik;Stephen A. Liebhaber

  • Inhibitor of apoptosis protein cIAP2 is essential for lipopolysaccharide-induced macrophage survival.

    Damiano Conte;Martin Holcik;Charles A. Lefebvre;Eric LaCasse

  • The internal ribosome entry site-mediated translation of antiapoptotic protein XIAP is modulated by the heterogeneous nuclear ribonucleoproteins C1 and C2.

    Martin Holčík;Bruce W. Gordon;Robert G. Korneluk

  • Distinct Regulation of Internal Ribosome Entry Site-mediated Translation following Cellular Stress Is Mediated by Apoptotic Fragments of eIF4G Translation Initiation Factor Family Members eIF4GI and p97/DAP5/NAT1

    Tara A. Nevins;Zdena M. Harder;Robert G. Korneluk;Martin Holčı́k

  • Mutations in TRNT1 cause congenital sideroblastic anemia with immunodeficiency, fevers, and developmental delay (SIFD)

    Pranesh K. Chakraborty;Klaus Schmitz-Abe;Erin K. Kennedy;Hapsatou Mamady

  • Translational induction of the inhibitor of apoptosis protein HIAP2 during endoplasmic reticulum stress attenuates cell death and is mediated via an inducible internal ribosome entry site element.

    Dinesh Warnakulasuriyarachchi;Sonia Cerquozzi;Herman H. Cheung;Martin Holcík

  • Cytoplasmic relocalization of heterogeneous nuclear ribonucleoprotein A1 controls translation initiation of specific mRNAs.

    Anne Cammas;Frédéric Pileur;Frédéric Pileur;Sophie Bonnal;Sophie Bonnal;Stephen M. Lewis

  • An internal ribosomal entry site mediates redox-sensitive translation of Nrf2

    Wenge Li;Nehal Thakor;Eugenia Y. Xu;Ying Huang

Frequent Co-Authors

Robert G. Korneluk
Robert G. Korneluk University of Ottawa
Alex MacKenzie
Alex MacKenzie Children's Hospital of Eastern Ontario
Bernard J. Jasmin
Bernard J. Jasmin University of Ottawa
Stéphan Vagner
Stéphan Vagner Institute Curie
Gary S. Goldfield
Gary S. Goldfield Children's Hospital of Eastern Ontario
Antonis E. Koromilas
Antonis E. Koromilas McGill University
Maria Hatzoglou
Maria Hatzoglou Case Western Reserve University
Nahum Sonenberg
Nahum Sonenberg McGill University
Mark S. Tremblay
Mark S. Tremblay Children's Hospital of Eastern Ontario
Jacek Majewski
Jacek Majewski McGill University

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