World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
86
Citations
28709
World Ranking
14080
National Ranking
535

Overview

Massimo Santoro is affiliated with the University of Naples Federico II in Italy and has a significant body of research primarily within the fields of Biochemistry, Genetics, and Molecular Biology, as well as Medicine. Their scientific focus encompasses various subfields, including Molecular Biology, Cell Biology, Cancer Research, Pulmonary and Respiratory Medicine, and Biochemistry.

Santoro's work extensively covers key topics such as Cancer, Hypoxia, and Metabolism; RNA modifications and cancer; Coenzyme Q10 studies and effects; Angiogenesis and VEGF in Cancer; Hippo pathway signaling and YAP/TAZ; Caveolin-1 and cellular processes; and Zebrafish Biomedical Research Applications.

Their recent publications illustrate the scope of their research interests. Notable papers include:

  • "The Antioxidant Role of Non-mitochondrial CoQ10: Mystery Solved!" (2020) published in Cell Metabolism
  • "A mitochondrial contribution to anti-inflammatory shear stress signaling in vascular endothelial cells" (2022) published in The Journal of Cell Biology
  • "Adaptive redox homeostasis in cutaneous melanoma" (2020) published in Redox Biology
  • "The origin and mechanisms of smooth muscle cell development in vertebrates" (2021) published in Development
  • "NCOA4 links iron bioavailability to DNA metabolism" (2022) published in Cell Reports

Frequent collaborators of Santoro include Roxana E. Oberkersch, Matteo Astone, Nicola Facchinello, Liaisan Arslanbaeva, and Giovanni Tosi. These coauthors have contributed to a number of joint publications, with counts ranging from three to nine shared works.

The scientist's publications often appear in reputable venues, with multiple contributions to journals such as Cell Metabolism, The Journal of Cell Biology, Redox Biology, Nature Metabolism, and Cell Death and Disease.

Best Publications

  • Revised American thyroid association guidelines for the management of medullary thyroid carcinoma

    Samuel A Wells;Sylvia L Asa;Henning Dralle;Rossella Elisei

  • Vandetanib in Patients With Locally Advanced or Metastatic Medullary Thyroid Cancer: A Randomized, Double-Blind Phase III Trial

    Samuel A. Wells;Bruce G. Robinson;Robert F. Gagel;Henning Dralle

  • BRAF Mutations in Thyroid Tumors Are Restricted to Papillary Carcinomas and Anaplastic or Poorly Differentiated Carcinomas Arising from Papillary Carcinomas

    Marina N. Nikiforova;Edna Teruko Kimura;Manoj Gandhi;Paul W. Biddinger

  • PTC is a novel rearranged form of the ret proto-oncogene and is frequently detected in vivo in human thyroid papillary carcinomas.

    Michele Grieco;Massimo Santoro;Maria Teresa Berlingieri;Rosa Marina Melillo

  • Activation of RET as a dominant transforming gene by germline mutations of MEN2A and MEN2B

    M Santoro;F Carlomagno;A Romano;D P Bottaro

  • Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27 Kip1 by PKB/Akt-mediated phosphorylation in breast cancer

    Giuseppe Viglietto;Maria Letizia Motti;Paola Bruni;Rosa Marina Melillo

  • BAY 43-9006 Inhibition of Oncogenic RET Mutants

    Francesca Carlomagno;Suresh Anaganti;Teresa Guida;Giuliana Salvatore

  • MicroRNA deregulation in human thyroid papillary carcinomas

    P Pallante;R Visone;R Visone;Manuela Ferracin;A Ferraro

  • A new oncogene in human thyroid papillary carcinomas and their lymph-nodal metastases

    A. Fusco;M. Grieco;M. Santoro;M. T. Berlingieri

  • Specific microRNAs are downregulated in human thyroid anaplastic carcinomas.

    R. Visone;P. Pallante;A. Vecchione;R. Cirombella

  • Association of BRAF V600E Mutation with Poor Clinicopathological Outcomes in 500 Consecutive Cases of Papillary Thyroid Carcinoma

    Cristiana Lupi;Riccardo Giannini;Clara Ugolini;Agnese Proietti

  • Ret oncogene activation in human thyroid neoplasms is restricted to the papillary cancer subtype.

    M Santoro;F Carlomagno;I D Hay;M A Herrmann

  • The RET/PTC-RAS-BRAF linear signaling cascade mediates the motile and mitogenic phenotype of thyroid cancer cells

    Rosa Marina Melillo;Maria Domenica Castellone;Valentina Guarino;Valentina De Falco

  • Mutation of the PIK3CA gene in anaplastic thyroid cancer.

    Ginesa García-Rostán;Angela M. Costa;Isabel Pereira-Castro;Giuliana Salvatore

  • High level expression of the HMGI (Y) gene during embryonic development.

    Gennaro Chiappetta;Virginia Avantaggiato;Roberta Visconti;Monica Fedele

  • High prevalence of RET/PTC rearrangements in Ukrainian and Belarussian post-Chernobyl thyroid papillary carcinomas: a strong correlation between RET/PTC3 and the solid-follicular variant.

    G. A. Thomas;H. Bunnell;H. A. Cook;E. D. Williams

  • Multiple Endocrine Neoplasia Type 2 and Familial Medullary Thyroid Carcinoma: An Update

    Samuel A. Wells;Furio Pacini;Bruce G. Robinson;Massimo Santoro

  • Analysis of BRAF point mutation and RET/PTC rearrangement refines the fine-needle aspiration diagnosis of papillary thyroid carcinoma.

    Giuliana Salvatore;Riccardo Giannini;Pinuccia Faviana;Alessia Caleo

  • Expression of the RET/PTC Fusion Gene as a Marker for Papillary Carcinoma in Hashimoto's Thyroiditis†

    Ari Wirtschafter;Richard Schmidt;David Rosen;Nandita Kundu

  • Frequent Activation of ret Protooncogene by Fusion with a New Activating Gene in Papillary Thyroid Carcinomas

    I. Bongarzone;M. G. Butti;S. Coronelli;M. G. Borrello

Frequent Co-Authors

Alfredo Fusco
Alfredo Fusco University of Naples Federico II
Rosa Marina Melillo
Rosa Marina Melillo University of Naples Federico II
Monica Fedele
Monica Fedele National Research Council (CNR)
Giuseppe Viglietto
Giuseppe Viglietto Magna Graecia University
Lorenzo Chiariotti
Lorenzo Chiariotti University of Naples Federico II
Fulvio Basolo
Fulvio Basolo University of Pisa
Neil Q. McDonald
Neil Q. McDonald The Francis Crick Institute
Carlo M. Croce
Carlo M. Croce The Ohio State University
Rossella Elisei
Rossella Elisei University of Pisa
James A. Fagin
James A. Fagin Memorial Sloan Kettering Cancer Center

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