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Genetics

D-Index
56
Citations
29094
World Ranking
3451
National Ranking
1494

Overview

Nicholas T. Ingolia is affiliated with the University of California, Berkeley in the United States. Their research primarily falls within the broad field of Biochemistry, Genetics, and Molecular Biology, with a specific focus on Molecular Biology as demonstrated by the majority of their publications.

The scientist has published extensively on topics related to RNA and protein synthesis mechanisms, RNA research and splicing, and CRISPR and genetic engineering. Other areas of interest include RNA modifications and cancer, fungal and yeast genetics research, as well as viral infections and immunology research. Their work also extends to the study of viral infectious diseases and gene expression in insects.

Among Nicholas T. Ingolia's recent papers are the following:

  • "Standardized annotation of translated open reading frames" (2022) published in Nature Biotechnology
  • "Ribosome stalling during selenoprotein translation exposes a ferroptosis vulnerability" (2022) published in Nature Chemical Biology
  • "The N-terminal domain of SARS-CoV-2 nsp1 plays key roles in suppression of cellular gene expression and preservation of viral gene expression" (2021) published in Cell Reports
  • "Dual targeting of DDX3 and eIF4A by the translation inhibitor rocaglamide A" (2020) published in Cell Chemical Biology
  • "Low-bias ncRNA libraries using ordered two-template relay: Serial template jumping by a modified retroelement reverse transcriptase" (2021) published in Proceedings of the National Academy of Sciences

Nicholas T. Ingolia frequently publishes in venues such as bioRxiv (Cold Spring Harbor Laboratory), eLife, Nature Chemical Biology, Cell Reports, and Cell Chemical Biology. These publication choices reflect a consistent contribution to journals at the intersection of molecular biology and biochemical research.

The scientist has collaborated extensively with several researchers, including Lucas Ferguson, Ryan Muller, Zuriah A. Meacham, J.H.D. Cate, and Kendra Reynaud, indicating a network of frequent coauthors contributing to their body of work.

Best Publications

  • Mammalian microRNAs predominantly act to decrease target mRNA levels

    Huili Guo;Nicholas T. Ingolia;Nicholas T. Ingolia;Jonathan S. Weissman;Jonathan S. Weissman;David P. Bartel

  • Genome-Wide Analysis in Vivo of Translation with Nucleotide Resolution Using Ribosome Profiling

    Nicholas T. Ingolia;Sina Ghaemmaghami;John R. S. Newman;Jonathan S. Weissman

  • Ribosome Profiling of Mouse Embryonic Stem Cells Reveals the Complexity and Dynamics of Mammalian Proteomes

    Nicholas T. Ingolia;Liana F. Lareau;Jonathan S. Weissman

  • The translational landscape of mTOR signalling steers cancer initiation and metastasis

    Andrew C. Hsieh;Yi Liu;Merritt P. Edlind;Nicholas T. Ingolia

  • The ribosome profiling strategy for monitoring translation in vivo by deep sequencing of ribosome-protected mRNA fragments.

    Nicholas T Ingolia;Gloria A Brar;Gloria A Brar;Silvia Rouskin;Silvia Rouskin;Anna M McGeachy;Anna M McGeachy

  • Ribosome Profiling Provides Evidence that Large Noncoding RNAs Do Not Encode Proteins

    Mitchell Guttman;Pamela Russell;Nicholas T. Ingolia;Jonathan S. Weissman

  • Ribosome profiling: new views of translation, from single codons to genome scale

    Nicholas T. Ingolia

  • Ribosome Profiling Reveals Pervasive Translation Outside of Annotated Protein-Coding Genes

    Nicholas T. Ingolia;Gloria A. Brar;Noam Stern-Ginossar;Michael S. Harris;Michael S. Harris

  • Decoding Human Cytomegalovirus

    Noam Stern-Ginossar;Ben Weisburd;Annette Michalski;Vu Thuy Khanh Le

  • The small molecule ISRIB reverses the effects of eIF2α phosphorylation on translation and stress granule assembly

    Carmela Sidrauski;Anna M McGeachy;Nicholas T Ingolia;Peter Walter

  • Identification of Long-Lived Proteins Reveals Exceptional Stability of Essential Cellular Structures

    Brandon H. Toyama;Jeffrey N. Savas;Sung Kyu Park;Michael S. Harris;Michael S. Harris

  • High-Resolution View of the Yeast Meiotic Program Revealed by Ribosome Profiling

    Gloria A. Brar;Moran Yassour;Moran Yassour;Nir Friedman;Aviv Regev

  • Molecular basis of infrared detection by snakes

    Elena O. Gracheva;Nicholas T. Ingolia;Nicholas T. Ingolia;Yvonne M. Kelly;Julio F. Cordero-Morales

  • Transcriptome-wide measurement of translation by ribosome profiling.

    Nicholas J. McGlincy;Nicholas T. Ingolia

  • Ribosome Footprint Profiling of Translation throughout the Genome.

    Nicholas T. Ingolia

  • Ubiquitination of stalled ribosome triggers ribosome-associated quality control

    Yoshitaka Matsuo;Ken Ikeuchi;Yasushi Saeki;Shintaro Iwasaki

  • Rocaglates convert DEAD-box protein eIF4A into a sequence-selective translational repressor

    Shintaro Iwasaki;Stephen N. Floor;Nicholas T. Ingolia

  • PtdIns4P synthesis by PI4KIIIα at the plasma membrane and its impact on plasma membrane identity

    Fubito Nakatsu;Jeremy M. Baskin;Jeeyun Chung;Lukas B. Tanner

  • Ganglion-specific splicing of TRPV1 underlies infrared sensation in vampire bats

    Elena O. Gracheva;Julio F. Cordero-Morales;José A. González-Carcacía;Nicholas T. Ingolia

  • Causal signals between codon bias, mRNA structure, and the efficiency of translation and elongation

    Cristina Pop;Silvi Rouskin;Nicholas T Ingolia;Lu Han

Frequent Co-Authors

Eric S. Lander
Eric S. Lander Broad Institute
Jamie H. D. Cate
Jamie H. D. Cate University of California, Berkeley
Toshifumi Inada
Toshifumi Inada Tohoku University
Yasushi Saeki
Yasushi Saeki Tokyo Metropolitan Institute of Medical Science
Mitchell Guttman
Mitchell Guttman California Institute of Technology
Nir Hacohen
Nir Hacohen Harvard University
Keiji Tanaka
Keiji Tanaka Tokyo Metropolitan Institute of Medical Science
Andrew W. Murray
Andrew W. Murray Harvard University
Alexander Marson
Alexander Marson University of California, San Francisco

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