His primary scientific interests are in Ribosome profiling, Translation, Genetics, Protein biosynthesis and Ribosome. The concepts of his Ribosome profiling study are interwoven with issues in Translational efficiency, Three prime untranslated region, Molecular biology and Genetic translation. His research integrates issues of Stop codon, Gene silencing, microRNA and Gene expression in his study of Three prime untranslated region.
His studies in Translation integrate themes in fields like Computational biology, Deep sequencing and Cell biology. Specifically, his work in Genetics is concerned with the study of Open reading frame. His Protein biosynthesis research is multidisciplinary, incorporating perspectives in Cell, Cellular component and Proteome.
The scientist’s investigation covers issues in Translation, Genetics, Ribosome profiling, Cell biology and Computational biology. The Translation study combines topics in areas such as RNA, Molecular biology, Transcriptome and Proteome. His work focuses on many connections between Ribosome profiling and other disciplines, such as Translational efficiency, that overlap with his field of interest in microRNA.
He interconnects Three prime untranslated region, Genetic translation, Gene silencing and Endogeny in the investigation of issues within microRNA. Nicholas T. Ingolia has included themes like Cell, Biogenesis, Ubiquitin ligase and Gene expression in his Cell biology study. His Computational biology research is multidisciplinary, relying on both Phenotype, CRISPR interference, Yeast and Genomics.
His primary areas of study are Translation, Cell biology, Computational biology, Eukaryotic translation and Gene. His Translation research is classified as research in Messenger RNA. His research on Messenger RNA often connects related topics like Protein biosynthesis.
He combines subjects such as Ribosome profiling, Ribosome, Biogenesis and Saccharomyces cerevisiae with his study of Cell biology. His studies deal with areas such as CRISPR interference, Phenotype, Yeast, Complementary DNA and microRNA as well as Computational biology. In his study, Repressor, Ferritin light chain, Psychological repression and Untranslated region is strongly linked to Initiation factor, which falls under the umbrella field of Eukaryotic translation.
Nicholas T. Ingolia mainly focuses on Computational biology, Eukaryotic translation, Gene, Translation and Initiation factor. His Computational biology research includes themes of CRISPR interference, Function, Yeast, Genomics and Essential gene. Translation is a subfield of Messenger RNA that Nicholas T. Ingolia studies.
In his work, Ribosome is strongly intertwined with Protein biosynthesis, which is a subfield of Messenger RNA. His study in Ribosome concentrates on Ribosome profiling and Ribosomal protein. Initiation factor is a subfield of Genetics that he investigates.
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Mammalian microRNAs predominantly act to decrease target mRNA levels
Huili Guo;Nicholas T. Ingolia;Nicholas T. Ingolia;Jonathan S. Weissman;Jonathan S. Weissman;David P. Bartel.
Genome-Wide Analysis in Vivo of Translation with Nucleotide Resolution Using Ribosome Profiling
Nicholas T. Ingolia;Sina Ghaemmaghami;John R. S. Newman;Jonathan S. Weissman.
Ribosome Profiling of Mouse Embryonic Stem Cells Reveals the Complexity and Dynamics of Mammalian Proteomes
Nicholas T. Ingolia;Liana F. Lareau;Jonathan S. Weissman.
The translational landscape of mTOR signalling steers cancer initiation and metastasis
Andrew C. Hsieh;Yi Liu;Merritt P. Edlind;Nicholas T. Ingolia.
The ribosome profiling strategy for monitoring translation in vivo by deep sequencing of ribosome-protected mRNA fragments.
Nicholas T Ingolia;Gloria A Brar;Gloria A Brar;Silvia Rouskin;Silvia Rouskin;Anna M McGeachy;Anna M McGeachy.
Nature Protocols (2012)
Ribosome Profiling Provides Evidence that Large Noncoding RNAs Do Not Encode Proteins
Mitchell Guttman;Pamela Russell;Nicholas T. Ingolia;Jonathan S. Weissman.
Ribosome profiling: new views of translation, from single codons to genome scale
Nicholas T. Ingolia.
Nature Reviews Genetics (2014)
Decoding Human Cytomegalovirus
Noam Stern-Ginossar;Ben Weisburd;Annette Michalski;Vu Thuy Khanh Le.
Ribosome Profiling Reveals Pervasive Translation Outside of Annotated Protein-Coding Genes
Nicholas T. Ingolia;Gloria A. Brar;Noam Stern-Ginossar;Michael S. Harris;Michael S. Harris.
Cell Reports (2014)
High-Resolution View of the Yeast Meiotic Program Revealed by Ribosome Profiling
Gloria A. Brar;Moran Yassour;Moran Yassour;Nir Friedman;Aviv Regev.
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