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Biology and Biochemistry

D-Index
66
Citations
16352
World Ranking
8631
National Ranking
113

Overview

Ola Larsson is affiliated with the Science for Life Laboratory in Sweden and has contributed extensively to the field of Biochemistry, Genetics, and Molecular Biology. Their research spans multiple subfields, notably Molecular Biology, Cancer Research, Oncology, Cell Biology, and Sociology and Political Science.

Larsson's work principally focuses on topics related to RNA modifications and cancer, RNA and protein synthesis mechanisms, RNA research and splicing, endoplasmic reticulum stress and disease, epigenetics and DNA methylation, cancer-related molecular mechanisms, and RNA regulation and disease.

Recent publications by Larsson include:

  • Adaptation to mitochondrial stress requires CHOP-directed tuning of ISR, 2021, Science Advances
  • Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growth, 2021, Nature Chemical Biology
  • The integrated stress response is tumorigenic and constitutes a therapeutic liability in KRAS-driven lung cancer, 2021, Nature Communications
  • Regulation of gene expression via translational buffering, 2021, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  • Deadenylase-dependent mRNA decay of GDF15 and FGF21 orchestrates food intake and energy expenditure, 2022, Cell Metabolism

Ola Larsson has frequently collaborated with several researchers in their field. Key coauthors include Ivan Topisirović, Krzysztof J. Szkop, Kathleen Watt, Maria Hatzoglou, and Laìa Masvidal.

Larsson's work is often published in venues such as bioRxiv (Cold Spring Harbor Laboratory), Nature Chemical Biology, Journal of Nonprofit Education and Leadership, Cancer Research, and Science Advances.

Best Publications

  • Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages

    James A. Timmons;James A. Timmons;James A. Timmons;Kristian Wennmalm;Ola Larsson;Tomas B. Walden;Tomas B. Walden

  • mTORC1-Mediated Cell Proliferation, But Not Cell Growth, Controlled by the 4E-BPs

    Ryan J. O. Dowling;Ivan Topisirovic;Tommy Alain;Michael Bidinosti

  • mTORC1 Controls Mitochondrial Activity and Biogenesis through 4E-BP-Dependent Translational Regulation

    Masahiro Morita;Simon Pierre Gravel;Valérie Chénard;Kristina Sikström

  • eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression

    Luc Furic;Liwei Rong;Ola Larsson;Ismaël Hervé Koumakpayi

  • Fibrotic extracellular matrix activates a profibrotic positive feedback loop

    Matthew W. Parker;Matthew W. Parker;Daniel Rossi;Mark Peterson;Karen Smith

  • mTOR coordinates protein synthesis, mitochondrial activity and proliferation.

    Masahiro Morita;Simon Pierre Gravel;Laura Hulea;Ola Larsson

  • Bactericidal antisense effects of peptide–PNA conjugates

    Liam Good;Satish Kumar Awasthi;Rikard Dryselius;Ola Larsson

  • Hypoxia-independent angiogenesis in adipose tissues during cold acclimation.

    Yuan Xue;Natasa Petrovic;Renhai Cao;Ola Larsson

  • Translational control of the innate immune response through IRF-7

    Rodney Colina;Mauro Costa-Mattioli;Ryan J. O. Dowling;Maritza Jaramillo

  • A stringent validation of mouse adipose tissue identity markers

    Jasper M. A. de Jong;Ola Larsson;Barbara Cannon;Jan Nedergaard

  • Pericyte-fibroblast transition promotes tumor growth and metastasis

    Kayoko Hosaka;Yunlong Yang;Takahiro Seki;Carina Fischer

  • mTOR Controls Mitochondrial Dynamics and Cell Survival via MTFP1

    Masahiro Morita;Masahiro Morita;Julien Prudent;Julien Prudent;Kaustuv Basu;Vanessa Goyon

  • Conserved GU-Rich Elements Mediate mRNA Decay by Binding to CUG-Binding Protein 1

    Irina A. Vlasova;Nuzha M. Tahoe;Danhua Fan;Ola Larsson

  • Translational control of immune responses: from transcripts to translatomes

    Ciriaco A Piccirillo;Eva Bjur;Ivan Topisirovic;Nahum Sonenberg

  • Phosphorylation of eIF4E promotes EMT and metastasis via translational control of SNAIL and MMP-3

    N Robichaud;S V del Rincon;B Huor;T Alain

  • Epigenetic activation of a subset of mRNAs by eIF4E explains its effects on cell proliferation.

    Yaël Mamane;Emmanuel Petroulakis;Yvan Martineau;Taka-Aki Sato

  • Insulin receptor expression by human prostate cancers

    Michael E. Cox;Martin E. Gleave;Mahvash Zakikhani;Robert H. Bell

  • PDGF-BB modulates hematopoiesis and tumor angiogenesis by inducing erythropoietin production in stromal cells

    Yuan Xue;Sharon Lim;Yunlong Yang;Zongwei Wang

  • nanoCAGE reveals 5′ UTR features that define specific modes of translation of functionally related MTOR-sensitive mRNAs

    Valentina Gandin;Laia Masvidal;Laura Hulea;Simon Pierre Gravel

  • Polysome fractionation and analysis of mammalian translatomes on a genome-wide scale.

    Valentina Gandin;Kristina Sikström;Tommy Alain;Masahiro Morita

Frequent Co-Authors

Ivan Topisirovic
Ivan Topisirovic McGill University
Nahum Sonenberg
Nahum Sonenberg McGill University
Peter B. Bitterman
Peter B. Bitterman University of Minnesota
Claes Wahlestedt
Claes Wahlestedt University of Miami
Michael Pollak
Michael Pollak McGill University
Zicai Liang
Zicai Liang Peking University
Julie St-Pierre
Julie St-Pierre McGill University
Grant A. McArthur
Grant A. McArthur Peter MacCallum Cancer Centre
Per-Olof Berggren
Per-Olof Berggren Karolinska Institute
Jerry Pelletier
Jerry Pelletier McGill University

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