World's Best Scientists 2026 revealed!
Julie St-Pierre

Julie St-Pierre

D-Index & Metrics

Biology and Biochemistry

D-Index
59
Citations
27749
World Ranking
12250
National Ranking
423

Overview

Julie St-Pierre is affiliated with McGill University in Canada, with a primary focus on research at the intersection of biochemistry, genetics, molecular biology, and medicine. Their work spans numerous subfields including molecular biology, cancer research, immunology, oncology, and physiology.

The scientist's research addresses several key topics related to cancer, metabolism, and molecular mechanisms. Main topics covered in their work include:

  • Cancer, Hypoxia, and Metabolism
  • Metabolism, Diabetes, and Cancer
  • Epigenetics and DNA Methylation
  • RNA modifications and cancer
  • Adipose Tissue and Metabolism
  • Immune cells in cancer
  • Cancer-related Molecular Pathways

Julie St-Pierre has contributed to research published in notable venues, with frequent publications in these journals:

  • Oncogene
  • Redox Biology
  • Scientific Reports
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research

Among their recent papers are significant studies including:

  • "Metabolic Fitness and Plasticity in Cancer Progression" (2020, Trends in Cancer)
  • "Estrogen-related receptors are targetable ROS sensors" (2020, Genes & Development)
  • "STAT1 potentiates oxidative stress revealing a targetable vulnerability that increases phenformin efficacy in breast cancer" (2021, Nature Communications)
  • "Perturbations of cancer cell metabolism by the antidiabetic drug canagliflozin" (2021, Neoplasia)
  • "Inhibition of DNMT1 and ERRα crosstalk suppresses breast cancer via derepression of IRF4" (2020, Oncogene)

Collaboration is an integral part of their research, with frequent co-authors including:

  • Shawn McGuirk
  • Peter M. Siegel
  • Lucía Minarrieta
  • Matthew G. Annis
  • Yannick Audet-Delage

Best Publications

  • AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1α

    Sibylle Jäger;Christoph Handschin;Julie St-Pierre;Bruce M Spiegelman

  • Suppression of Reactive Oxygen Species and Neurodegeneration by the PGC-1 Transcriptional Coactivators

    Julie St-Pierre;Stavit Drori;Marc Uldry;Jessica M. Silvaggi

  • Topology of Superoxide Production from Different Sites in the Mitochondrial Electron Transport Chain

    Julie St-Pierre;Julie A. Buckingham;Stephen J. Roebuck;Martin D. Brand

  • Superoxide activates mitochondrial uncoupling proteins

    Karim S. Echtay;Damien Roussel;Julie St-Pierre;Mika B. Jekabsons

  • Defects in Adaptive Energy Metabolism with CNS-Linked Hyperactivity in PGC-1α Null Mice

    Jiandie Lin;Pei Hsuan Wu;Paul T. Tarr;Katrin S. Lindenberg

  • mTORC1 Controls Mitochondrial Activity and Biogenesis through 4E-BP-Dependent Translational Regulation

    Masahiro Morita;Simon Pierre Gravel;Valérie Chénard;Kristina Sikström

  • Complementary action of the PGC-1 coactivators in mitochondrial biogenesis and brown fat differentiation

    Marc Uldry;Wenli Yang;Julie St-Pierre;Jiandie Lin

  • A roadmap for interpreting 13 C metabolite labeling patterns from cells

    Joerg M. Buescher;Maciek R. Antoniewicz;Laszlo G. Boros;Shawn C Burgess

  • Bioenergetic Analysis of Peroxisome Proliferator-activated Receptor γ Coactivators 1α and 1β (PGC-1α and PGC-1β) in Muscle Cells

    Julie St-Pierre;Jiandie Lin;Stefan Krauss;Paul T. Tarr

  • PGC1α and mitochondrial metabolism--emerging concepts and relevance in ageing and neurodegenerative disorders.

    Shane Austin;Julie St-Pierre

  • Superoxide-mediated activation of uncoupling protein 2 causes pancreatic β cell dysfunction

    Stefan Krauss;Chen-Yu Zhang;Luca Scorrano;Louise T. Dalgaard

  • PDK1-Dependent Metabolic Reprogramming Dictates Metastatic Potential in Breast Cancer

    Fanny Dupuy;Sébastien Tabariès;Sylvia Andrzejewski;Zhifeng Dong

  • mTOR coordinates protein synthesis, mitochondrial activity and proliferation.

    Masahiro Morita;Simon Pierre Gravel;Laura Hulea;Ola Larsson

  • AMPK Maintains Cellular Metabolic Homeostasis through Regulation of Mitochondrial Reactive Oxygen Species.

    Rebecca C Rabinovitch;Bozena Samborska;Brandon Faubert;Eric H Ma

  • Metformin directly acts on mitochondria to alter cellular bioenergetics

    Sylvia Andrzejewski;Simon-Pierre Gravel;Michael Pollak;Julie St-Pierre

  • Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1α: modulation by p38 MAPK

    Melina Fan;James Rhee;Julie St-Pierre;Christoph Handschin

  • Superoxide and hydrogen peroxide production by Drosophila mitochondria.

    Satomi Miwa;Julie St-Pierre;Linda Partridge;Martin D Brand

  • miR-378∗ Mediates Metabolic Shift in Breast Cancer Cells via the PGC-1β/ERRγ Transcriptional Pathway

    Lillian J. Eichner;Marie Claude Perry;Catherine R. Dufour;Nicholas Bertos

  • mTOR Controls Mitochondrial Dynamics and Cell Survival via MTFP1

    Masahiro Morita;Masahiro Morita;Julien Prudent;Julien Prudent;Kaustuv Basu;Vanessa Goyon

  • Gestational diabetes mellitus epigenetically affects genes predominantly involved in metabolic diseases.

    Stephanie-May Ruchat;Andrée-Anne Houde;Grégory Voisin;Julie St-Pierre

Frequent Co-Authors

Michael Pollak
Michael Pollak McGill University
Vincent Giguère
Vincent Giguère McGill University
Ivan Topisirovic
Ivan Topisirovic McGill University
Russell G. Jones
Russell G. Jones McGill University
Peter M. Siegel
Peter M. Siegel McGill University
Daniel Gaudet
Daniel Gaudet University of Montreal
Ola Larsson
Ola Larsson Science for Life Laboratory
Marie-France Hivert
Marie-France Hivert Harvard University
Celia M. T. Greenwood
Celia M. T. Greenwood McGill University
Christoph Handschin
Christoph Handschin University of Basel

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