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Biology and Biochemistry

D-Index
56
Citations
12827
World Ranking
14315
National Ranking
6032

Overview

Donald W. Hilgemann is affiliated with The University of Texas Southwestern Medical Center in the United States. Their research spans multiple domains within biochemistry, genetics, molecular biology, and medicine, emphasizing molecular and cellular physiology.

Their recent work includes studies published between 2021 and 2024 across several scientific venues. Notable papers include:

  • TMEM16F and dynamins control expansive plasma membrane reservoirs, 2021, Nature Communications
  • Constitutive Plasma Membrane Turnover in T-REx293 cells via Ordered Membrane Domain Endocytosis under Mitochondrial Control, 2024, bioRxiv (Cold Spring Harbor Laboratory)
  • Longitudinal diffusion barriers imposed by myofilaments and mitochondria in murine cardiac myocytes, 2023, The Journal of General Physiology
  • Correction: Longitudinal diffusion barriers imposed by myofilaments and mitochondria in murine cardiac myocytes, 2023, The Journal of General Physiology
  • Pore-like diffusion barriers in murine cardiac myocytes, 2023, bioRxiv (Cold Spring Harbor Laboratory)

Their frequent coauthors include Christine Deisl, Jay H. Chung, Ruhma Syeda, Michael Fine, and Orson W. Moe.

Hilgemann's research contributions are featured predominantly in the following publication venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Journal of General Physiology
  • Nature Communications

Their work covers various subfields of study within biochemistry and medicine, including molecular biology, cell biology, physiology, cardiology and cardiovascular medicine, as well as neurology.

Main topics addressed in Hilgemann's research are:

  • Cellular transport and secretion
  • Erythrocyte function and pathophysiology
  • Lipid membrane structure and behavior
  • Neurological diseases and metabolism
  • Mitochondrial function and pathology
  • Phosphodiesterase function and regulation
  • Neuroscience and neuropharmacology research

Best Publications

  • Direct activation of inward rectifier potassium channels by PIP2 and its stabilization by Gβγ

    Chou-Long Huang;Siyi Feng;Donald W. Hilgemann

  • Regulation of Cardiac Na+,Ca2+ Exchange and KATP Potassium Channels by PIP2

    Donald W. Hilgemann;Rebecca Ball

  • The complex and intriguing lives of PIP2 with ion channels and transporters.

    Donald W. Hilgemann;Siyi Feng;Cem Nasuhoglu

  • Regulation and deregulation of cardiac Na(+)-Ca2+ exchange in giant excised sarcolemmal membrane patches.

    Donald W. Hilgemann

  • Steady-state and dynamic properties of cardiac sodium-calcium exchange. Sodium-dependent inactivation.

    Donald W. Hilgemann;Satoshi Matsuoka;Georg A. Nagel;Anthony Collins

  • Initial localization of regulatory regions of the cardiac sarcolemmal Na(+)-Ca2+ exchanger.

    Satoshi Matsuoka;Debora A. Nicoll;Robert F. Reilly;Donald W. Hilgemann

  • Phospholipase C in Living Cells: Activation, Inhibition, Ca2+ Requirement, and Regulation of M Current

    Lisa F. Horowitz;Wiebke Hirdes;Wiebke Hirdes;Byung Chang Suh;Donald W. Hilgemann

  • Steady-state and dynamic properties of cardiac sodium-calcium exchange. Secondary modulation by cytoplasmic calcium and ATP.

    Donald W. Hilgemann;Anthony Collins;Satoshi Matsuoka

  • Identification of a peptide inhibitor of the cardiac sarcolemmal Na+-Ca2+ exchanger

    Zhaoping Li;D. A. Nicoll;A. Collins;D. W. Hilgemann

  • Excitation-contraction coupling and extracellular calcium transients in rabbit atrium: reconstruction of basic cellular mechanisms

    Donald W Hilgemann;D. Noble

  • Cloning and characterization of a novel Mg2+/H+ exchanger

    Orit Shaul;Donald W. Hilgemann;Janice de‐Almeida‐Engler;Marc Van Montagu

  • Functional comparison of the three isoforms of the Na+/Ca2+ exchanger (NCX1, NCX2, NCX3).

    Bettina Linck;Zhiyong Qiu;Zhaoping He;Qiusheng Tong

  • Regulation of Kv7 (KCNQ) K+ Channel Open Probability by Phosphatidylinositol 4,5-Bisphosphate

    Yang Li;Nikita Gamper;Donald W. Hilgemann;Mark S. Shapiro

  • Charge movement during Na+ translocation by native and cloned cardiac Na+/Ca2+ exchanger.

    Donald W. Hilgemann;Debora A. Nicoll;Kenneth D. Philipson

  • Channel-like function of the Na,K pump probed at microsecond resolution in giant membrane patches

    Donald W. Hilgemann

  • CYTOPLASMIC ATP-DEPENDENT REGULATION OF ION TRANSPORTERS AND CHANNELS: Mechanisms and Messengers

    Donald W. Hilgemann

  • The giant cardiac membrane patch method : stimulation of outward Na+-Ca2+ exchange current by MgATP

    A Collins;A V Somlyo;D W Hilgemann

  • Multiple transport modes of the cardiac Na+/Ca2+ exchanger.

    Tong Mook Kang;Donald W. Hilgemann

  • Gat1 (Gaba:Na+:Cl−) Cotransport Function Steady State Studies in Giant Xenopus Oocyte Membrane Patches

    Chin Chih Lu;Donald W. Hilgemann

  • Nonradioactive analysis of phosphatidylinositides and other anionic phospholipids by anion-exchange high-performance liquid chromatography with suppressed conductivity detection.

    Cem Nasuhoglu;Siyi Feng;Janping Mao;Masaya Yamamoto

Frequent Co-Authors

Kenneth D. Philipson
Kenneth D. Philipson University of California, Los Angeles
Mary Collins
Mary Collins Queen Mary University of London
Orson W. Moe
Orson W. Moe The University of Texas Southwestern Medical Center
Chou Long Huang
Chou Long Huang University of Iowa Hospitals and Clinics
Dirk Inzé
Dirk Inzé Ghent University
Sandra L. Hofmann
Sandra L. Hofmann The University of Texas Southwestern Medical Center
Helen L. Yin
Helen L. Yin The University of Texas Southwestern Medical Center
Michael L. J. Ashford
Michael L. J. Ashford University of Dundee
Joseph P. Albanesi
Joseph P. Albanesi The University of Texas Southwestern Medical Center
Maurine E. Linder
Maurine E. Linder Cornell University

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