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Biology and Biochemistry

D-Index
83
Citations
21016
World Ranking
3570
National Ranking
1786

Overview

Kenneth D. Philipson is affiliated with the University of California, Los Angeles in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a particular emphasis on Cardiology and Cardiovascular Medicine as well as Molecular Biology. Subfields include Pathology and Forensic Medicine, Cellular and Molecular Neuroscience, and Biomedical Engineering.

The scientist's work focuses on several main topics, including:

  • Cardiac electrophysiology and arrhythmias
  • Ion channel regulation and function
  • Cardiac Ischemia and Reperfusion
  • Neuroscience and Neural Engineering
  • Cardiac pacing and defibrillation studies
  • Membrane-based Ion Separation Techniques
  • Analytical Chemistry and Sensors

Philipson has published extensively in several scientific journals, with frequent venues including:

  • Biophysical Journal
  • Journal of the American Heart Association
  • Cell Calcium
  • Proceedings of the National Academy of Sciences
  • Circulation

Recent papers authored or co-authored by Philipson are:

  • "Acute Genetic Ablation of Cardiac Sodium/Calcium Exchange in Adult Mice: Implications for Cardiomyocyte Calcium Regulation, Cardioprotection, and Arrhythmia" (2021), Journal of the American Heart Association
  • "Na/Ca exchange in the atrium: Role in sinoatrial node pacemaking and excitation-contraction coupling" (2020), Cell Calcium
  • "Regulation of Na/Ca exchange by cytoplasmic protons modifies intracellular calcium dynamics and the cardiac response to ischemia" (2025), Proceedings of the National Academy of Sciences
  • "Effects of PMCA1 knockout on ventricular cardiomyocyte calcium homeostasis" (2023), Biophysical Journal
  • "Sodium-Calcium Exchanger (NCX1) is Essential for Atrioventricular Node Automaticity and Conduction, as Revealed through Atrial-Specific Knockout of NCX1" (2020), Biophysical Journal

They have collaborated frequently with the following co-authors:

  • Michela Ottolia
  • Joshua I. Goldhaber
  • Devina Gonzalez
  • Sabine Lotteau
  • Liang Li

Best Publications

  • Molecular cloning and functional expression of the cardiac sarcolemmal Na(+)-Ca2+ exchanger

    Debora A. Nicoll;Stefano Longoni;Kenneth D. Philipson

  • Sodium-calcium exchange: a molecular perspective.

    Kenneth D. Philipson;Debora A. Nicoll

  • Tissue specificity and alternative splicing of the Na+/Ca2+ exchanger isoforms NCX1, NCX2, and NCX3 in rat

    B. D. Quednau;D. A. Nicoll;K. D. Philipson

  • Cloning of a Third Mammalian Na+-Ca2+ Exchanger, NCX3

    Debora A. Nicoll;Beate D. Quednau;Zhiyong Qui;Yu-Rong Xia

  • Cloning of the NCX2 isoform of the plasma membrane Na+-Ca2+ exchanger

    Zhaoping Li;S. Matsuoka;L. V. Hryshko;D. A. Nicoll

  • Initial localization of regulatory regions of the cardiac sarcolemmal Na(+)-Ca2+ exchanger.

    Satoshi Matsuoka;Debora A. Nicoll;Robert F. Reilly;Donald W. Hilgemann

  • Identification of a peptide inhibitor of the cardiac sarcolemmal Na+-Ca2+ exchanger

    Zhaoping Li;D. A. Nicoll;A. Collins;D. W. Hilgemann

  • Effects of pH on Na+-Ca2+ exchange in canine cardiac sarcolemmal vesicles.

    K D Philipson;M M Bersohn;A Y Nishimoto

  • Functional comparison of the three isoforms of the Na+/Ca2+ exchanger (NCX1, NCX2, NCX3).

    Bettina Linck;Zhiyong Qiu;Zhaoping He;Qiusheng Tong

  • Effects of Overexpression of the Na+-Ca2+ Exchanger on [Ca2+]i Transients in Murine Ventricular Myocytes

    Atsushi Yao;Zhi Su;Akihiko Nonaka;Iram Zubair

  • Charge movement during Na+ translocation by native and cloned cardiac Na+/Ca2+ exchanger.

    Donald W. Hilgemann;Debora A. Nicoll;Kenneth D. Philipson

  • Distribution of the Na(+)-Ca2+ exchange protein in mammalian cardiac myocytes: an immunofluorescence and immunocolloidal gold-labeling study.

    JS Frank;G Mottino;D Reid;RS Molday

  • Identification of the high affinity Ca(2+)-binding domain of the cardiac Na(+)-Ca2+ exchanger.

    D.O. Levitsky;D.A. Nicoll;K.D. Philipson

  • Purification of the cardiac Na+Ca2+ exchange protein

    Kenneth D. Philipson;Stefano Longoni;Robert Ward

  • A NEW TOPOLOGICAL MODEL OF THE CARDIAC SARCOLEMMAL NA+-CA2+ EXCHANGER

    Debora A. Nicoll;Michela Ottolia;Liyan Lu;Yujuan Lu

  • Overexpression of the Cardiac Na+/Ca2+ Exchanger Increases Susceptibility to Ischemia/Reperfusion Injury in Male, but Not Female, Transgenic Mice

    Heather R. Cross;Liyan Lu;Charles Jr Steenbergen;Kenneth D. Philipson

  • Regulation of the cardiac Na(+)-Ca2+ exchanger by Ca2+. Mutational analysis of the Ca(2+)-binding domain.

    S Matsuoka;D A Nicoll;L V Hryshko;D O Levitsky

  • Coupling of the Na+/Ca2+ exchanger, Na+/K+ pump and sarcoplasmic reticulum in smooth muscle.

    Edwin D. W. Moore;Elaine F. Etter;Kenneth D. Philipson;Walter A. Carrington

  • Regulation of the Cardiac Na+-Ca2+ Exchanger by the Endogenous XIP Region

    Satoshi Matsuoka;Debora A. Nicoll;Zhaoping He;Kenneth D. Philipson

  • Mutational Analysis of the Ca2+-binding Domain

    Satoshi Matsuoka;Debora A. Nicoll;Larry V. Hryshko;Dmitri O. Levitsky

Frequent Co-Authors

Joshua I. Goldhaber
Joshua I. Goldhaber Cedars-Sinai Medical Center
Donald W. Hilgemann
Donald W. Hilgemann The University of Texas Southwestern Medical Center
Donald M. Bers
Donald M. Bers University of California, Davis
James N. Weiss
James N. Weiss University of California, Los Angeles
Mordecai P. Blaustein
Mordecai P. Blaustein University of Maryland, Baltimore
Duilio Cascio
Duilio Cascio University of California, Los Angeles
Michael I. Kotlikoff
Michael I. Kotlikoff Cornell University
Jerry B. Lingrel
Jerry B. Lingrel University of Cincinnati
Kenneth Sauer
Kenneth Sauer Lawrence Berkeley National Laboratory
Martin Friedlander
Martin Friedlander Scripps Research Institute

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