2026 Duilio Cascio: Biology and Biochemistry Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Biology and Biochemistry	76	5035	4650	2415	2171	407	21499

Overview

Duilio Cascio is affiliated with the University of California, Los Angeles in the United States. Their primary field of study is Biochemistry, Genetics and Molecular Biology, with an emphasis on Molecular Biology, Materials Chemistry, Insect Science, Physiology, and Structural Biology.

The scientist's main research topics include:

RNA Research and Splicing
Enzyme Structure and Function
RNA modifications and cancer
RNA and protein synthesis mechanisms
Alzheimer's disease research and treatments
Advanced Electron Microscopy Techniques and Applications
Insect Resistance and Genetics

Duilio Cascio has published research in multiple scientific venues. Frequent publication venues include:

Journal of Biological Chemistry
Nature Communications
Proceedings of the National Academy of Sciences
bioRxiv (Cold Spring Harbor Laboratory)
Acta Crystallographica Section D Structural Biology

Recent notable papers authored by or involving Duilio Cascio are:

"CryoEM structure of the low-complexity domain of hnRNPA2 and its conversion to pathogenic amyloid" (2020, Nature Communications)
"Prospecting for natural products by genome mining and microcrystal electron diffraction" (2021, Nature Chemical Biology)
"Structure-based design of nanobodies that inhibit seeding of Alzheimer's patient-extracted tau fibrils" (2023, Proceedings of the National Academy of Sciences)
"Cryo-EM structure determination of small therapeutic protein targets at 3 Å-resolution using a rigid imaging scaffold" (2023, Proceedings of the National Academy of Sciences)
"Serial femtosecond crystallography on in vivo-grown crystals drives elucidation of mosquitocidal Cyt1Aa bioactivation cascade" (2020, Nature Communications)

Frequent collaborators of Duilio Cascio include:

M.R. Sawaya
David Eisenberg
David R. Boyer
Romany Abskharon
Brendan J. Mahoney

Best Publications

A mutation in the vesicle-trafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis.

Agnes L. Nishimura;Miguel Mitne-Neto;Helga C.A. Silva;Helga C.A. Silva;Antônio Richieri-Costa

1167
Citations
Synthesis, Structure, and Metalation of Two New Highly Porous Zirconium Metal-Organic Frameworks

William Morris;Boris Volosskiy;Selcuk Demir;Felipe Gándara

958
Citations
Toward the structural genomics of complexes: Crystal structure of a PE/PPE protein complex from Mycobacterium tuberculosis

Michael Strong;Michael R. Sawaya;Shuishu Wang;Martin Phillips

849
Citations
Structure of the toxic core of α-synuclein from invisible crystals

Jose A. Rodriguez;Magdalena I. Ivanova;Michael R. Sawaya;Duilio Cascio

659
Citations
The crystal structure of mouse VDAC1 at 2.3 Å resolution reveals mechanistic insights into metabolite gating

Rachna Ujwal;Duilio Cascio;Jacques-Philippe Colletier;Salem Faham

624
Citations
Atomic view of a toxic amyloid small oligomer.

Arthur Laganowsky;Cong Liu;Michael R. Sawaya;Julian P. Whitelegge

624
Citations
Accurate design of megadalton-scale two-component icosahedral protein complexes.

Jacob B. Bale;Shane Gonen;Shane Gonen;Yuxi Liu;William Sheffler

608
Citations
The Crystal Structure of a Sodium Galactose Transporter Reveals Mechanistic Insights into Na+/Sugar Symport

Salem Faham;Akira Watanabe;Gabriel Mercado Besserer;Duilio Cascio

590
Citations
Atomic structures of low-complexity protein segments reveal kinked β sheets that assemble networks

Michael P. Hughes;Michael R. Sawaya;David R. Boyer;Lukasz Goldschmidt

469
Citations
Molecular basis for amyloid-beta polymorphism.

Jacques-Philippe Colletier;Arthur Laganowsky;Meytal Landau;Minglei Zhao

438
Citations
Crystal structure of a synthetic triple-stranded alpha-helical bundle

Brett Lovejoy;Seunghyon Choe;Duilio Cascio;Donald K. McRorie

403
Citations
Atomic structure of the cross-beta spine of islet amyloid polypeptide (amylin).

Jed J.W. Wiltzius;Stuart A. Sievers;Michael R. Sawaya;Duilio Cascio

382
Citations
Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function.

Arthur Laganowsky;Justin L. P. Benesch;Justin L. P. Benesch;Meytal Landau;Meytal Landau;Linlin Ding

334
Citations
Engineering an allosteric transcription factor to respond to new ligands

Noah D Taylor;Alexander S Garruss;Alexander S Garruss;Rocco Moretti;Sum Chan

322
Citations
Crystal structures of spin labeled T4 lysozyme mutants: implications for the interpretation of EPR spectra in terms of structure.

Ralf Langen;Kyoung Joon Oh;Duilio Cascio;Wayne L. Hubbell

318
Citations
The crystal structure of a cyanobacterial water-soluble carotenoid binding protein.

Cheryl A Kerfeld;Michael R Sawaya;Vishnu Brahmandam;Duilio Cascio

312
Citations
Structure of a 16-nm cage designed by using protein oligomers.

Yen-Ting Lai;Duilio Cascio;Todd O. Yeates

303
Citations
Molecular mechanisms for protein-encoded inheritance

Jed J W Wiltzius;Meytal Landau;Rebecca Nelson;Michael R Sawaya

297
Citations
Site-directed spin labeling of a genetically encoded unnatural amino acid

Mark R. Fleissner;Eric M. Brustad;Eric M. Brustad;Tamás Kálai;Christian Altenbach

294
Citations
Structure-based inhibitors of tau aggregation

P.M. Seidler;D.R. Boyer;D.R. Boyer;J.A. Rodriguez;J.A. Rodriguez;M.R. Sawaya;M.R. Sawaya

285
Citations