What is he best known for?
The fields of study he is best known for:
Protein structure, Crystallography, Biochemistry, Biophysics and Stereochemistry are his primary areas of study.
His Protein structure study integrates concerns from other disciplines, such as Fibril, Genetics, Peptide sequence and Microscopy.
His study in Crystallography is interdisciplinary in nature, drawing from both Molecule, Diffraction and Amyloid.
His Biophysics research is multidisciplinary, incorporating elements of Dimer, Guanine and Chaperone.
His biological study spans a wide range of topics, including Side chain, Electron paramagnetic resonance, Helix and Hydrogen bond.
His studies deal with areas such as Antiparallel, Crystallin and Beta sheet as well as Heat shock protein.
His most cited work include:
- A mutation in the vesicle-trafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis. (755 citations)
- Toward the structural genomics of complexes: Crystal structure of a PE/PPE protein complex from Mycobacterium tuberculosis (611 citations)
- Synthesis, Structure, and Metalation of Two New Highly Porous Zirconium Metal-Organic Frameworks (485 citations)
What are the main themes of his work throughout his whole career to date?
Duilio Cascio mainly focuses on Crystallography, Biochemistry, Biophysics, Protein structure and Crystal structure.
His study focuses on the intersection of Crystallography and fields such as Side chain with connections in the field of Electron paramagnetic resonance.
Duilio Cascio works on Biochemistry which deals in particular with Saccharomyces cerevisiae.
In his work, Structural biology, Protein aggregation and P3 peptide is strongly intertwined with Amyloid, which is a subfield of Biophysics.
His studies in Protein structure integrate themes in fields like Peptide sequence, Protein subunit, Stereochemistry and Chaperone.
As part of the same scientific family, he usually focuses on Stereochemistry, concentrating on Binding site and intersecting with Plasma protein binding.
He most often published in these fields:
- Crystallography (32.49%)
- Biochemistry (27.92%)
- Biophysics (25.89%)
What were the highlights of his more recent work (between 2017-2021)?
- Biophysics (25.89%)
- Fibril (7.11%)
- Amyloid (10.66%)
In recent papers he was focusing on the following fields of study:
Duilio Cascio focuses on Biophysics, Fibril, Amyloid, Crystallography and Biochemistry.
His Biophysics study incorporates themes from Plasma protein binding, Amyloid beta, Mutation, Liquid-crystal display and Protein structure.
Duilio Cascio has included themes like Polymorphism, Cystic kidney, Synchrotron and Diffraction in his Protein structure study.
His Fibril research incorporates elements of Protein aggregation, Neurodegeneration, Tauopathy, Structural biology and Isomerization.
His Amyloid study combines topics in areas such as Beta sheet, Self-healing hydrogels, Organelle and DNA-binding protein.
Particularly relevant to Crystal structure is his body of work in Crystallography.
Between 2017 and 2021, his most popular works were:
- Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. (84 citations)
- Sub-ångström cryo-EM structure of a prion protofibril reveals a polar clasp (43 citations)
- Structure-based inhibitors of amyloid beta core suggest a common interface with tau. (24 citations)
In his most recent research, the most cited papers focused on:
His main research concerns Amyloid, Fibril, Biophysics, Mutation and Crystallography.
His research integrates issues of Progressive supranuclear palsy, Structural biology, Epitope and Peptide in his study of Amyloid.
Duilio Cascio has researched Structural biology in several fields, including Tau protein, Neurodegeneration, Tauopathy and Protein aggregation.
Duilio Cascio combines subjects such as Chemical biology, Amyloid β, Beta sheet and DNA-binding protein with his study of Biophysics.
His Mutation research includes elements of Ribonucleoprotein, Steric effects and Hydrogen bond.
The concepts of his Crystallography study are interwoven with issues in Yield, In vivo and Femtosecond.
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