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Biology and Biochemistry

D-Index
64
Citations
16285
World Ranking
9581
National Ranking
4230

Overview

Martin Friedlander is affiliated with the Scripps Research Institute in the United States and has a significant publication record primarily in the fields of medicine and biochemistry, genetics, and molecular biology. Their research mainly focuses on ophthalmology, with particular attention to retinal diseases and related areas.

The scientist's work spans several subfields, including ophthalmology, molecular biology, radiology, nuclear medicine and imaging, immunology, and cell biology. Their research often addresses topics related to retinal diseases and treatments, retinal development and disorders, retinal imaging and analysis, glaucoma and retinal disorders, retinal and optic conditions, neuroinflammation and neurodegeneration mechanisms, as well as interferon and immune responses.

Frequent publication venues where the scientist has contributed multiple publications include bioRxiv (Cold Spring Harbor Laboratory), Ophthalmology Science, Glia, Communications Biology, and JCI Insight.

Some of the recent papers published by Martin Friedlander are:

  • Cell-specific cis-regulatory elements and mechanisms of non-coding genetic disease in human retina and retinal organoids, 2022, Developmental Cell
  • An allosteric peptide inhibitor of HIF-1α regulates hypoxia-induced retinal neovascularization, 2020, Proceedings of the National Academy of Sciences
  • Serine biosynthesis defect due to haploinsufficiency of PHGDH causes retinal disease, 2021, Nature Metabolism
  • Identification of genetic factors influencing metabolic dysregulation and retinal support for MacTel, a retinal disorder, 2021, Communications Biology
  • Retinal microglia are critical for subretinal neovascular formation, 2020, JCI Insight

The scientist has collaborated frequently with several coauthors, including Kevin Eade, Edith Aguilar, Sarah Giles, Roberto Bonelli, and Simone Tzaridis, demonstrating ongoing professional partnerships in research projects.

Best Publications

  • Definition of Two Angiogenic Pathways by Distinct αv Integrins

    Martin Friedlander;Peter C. Brooks;Robert W. Shaffer;Christine M. Kincaid

  • Disruption of Angiogenesis by PEX, a Noncatalytic Metalloproteinase Fragment with Integrin Binding Activity

    Peter C Brooks;Steve Silletti;Tami L von Schalscha;Martin Friedlander

  • Involvement of integrins alpha v beta 3 and alpha v beta 5 in ocular neovascular diseases.

    Martin Friedlander;Chandra L. Theesfeld;Miyuki Sugita;Marcus Fruttiger

  • The receptor for transepithelial transport of IgA and IgM contains multiple immunoglobulin-like domains

    Keith E. Mostov;Martin Friedlander;Günter Blobel

  • Regulation of angiogenesis by tissue factor cytoplasmic domain signaling

    Mattias Belting;Michael I Dorrell;Staffan Sandgren;Edith Aguilar

  • Targeted deletion of Vegfa in adult mice induces vision loss

    Toshihide Kurihara;Peter D. Westenskow;Stephen Bravo;Edith Aguilar

  • Bone marrow-derived stem cells target retinal astrocytes and can promote or inhibit retinal angiogenesis.

    Atsushi Otani;Karen Kinder;Karla Ewalt;Francella J Otero

  • Rescue of retinal degeneration by intravitreally injected adult bone marrow–derived lineage-negative hematopoietic stem cells

    Atsushi Otani;Michael Ian Dorrell;Karen Kinder;Stacey K. Moreno

  • A human aminoacyl-tRNA synthetase as a regulator of angiogenesis

    Keisuke Wakasugi;Bonnie M. Slike;John Hood;Atsushi Otani

  • Retinal Vascular Development Is Mediated by Endothelial Filopodia, a Preexisting Astrocytic Template and Specific R-Cadherin Adhesion

    Michael I Dorrell;Edith Aguilar;Martin Friedlander

  • Fibrosis and diseases of the eye.

    Martin Friedlander

  • Myeloid progenitors differentiate into microglia and promote vascular repair in a model of ischemic retinopathy

    Matthew R. Ritter;Eyal Banin;Stacey K. Moreno;Edith Aguilar

  • Prospective Study of Infantile Haemangiomas: Incidence, Clinical Characteristics and Association With Placental Anomalies

    A. Munden;R. Butschek;W.L. Tom;W.L. Tom;J. S. Marshall

  • A homing mechanism for bone marrow–derived progenitor cell recruitment to the neovasculature

    Hui Jin;Aparna Aiyer;Jingmei Su;Per Borgstrom

  • Retinal lipid and glucose metabolism dictates angiogenesis through the lipid sensor Ffar1

    Jean-Sébastien Joyal;Ye Sun;Marin L Gantner;Zhuo Shao

  • Humanized Mice Reveal Differential Immunogenicity of Cells Derived from Autologous Induced Pluripotent Stem Cells.

    Tongbiao Zhao;Tongbiao Zhao;Zhen-ning Zhang;Peter D. Westenskow;Dilyana Todorova

  • Hypoxia-induced metabolic stress in retinal pigment epithelial cells is sufficient to induce photoreceptor degeneration

    Toshihide Kurihara;Peter D. Westenskow;Marin L. Gantner;Yoshihiko Usui

  • Bovine opsin has more than one signal sequence.

    Martin Friedlander;Günter Blobel

  • Insulin-like growth factor 2 and potential regulators of hemangioma growth and involution identified by large-scale expression analysis

    Matthew R. Ritter;Michael I. Dorrell;Joseph Edmonds;Sheila Fallon Friedlander;Sheila Fallon Friedlander;Sheila Fallon Friedlander

  • Functional Adult Myocardium in the Absence of Na+-Ca2+ Exchange. Cardiac-Specific Knockout of NCX1

    Scott A. Henderson;Joshua I. Goldhaber;Jessica M. So;Tieyan Han

Frequent Co-Authors

David A. Cheresh
David A. Cheresh University of California, San Diego
Gary Siuzdak
Gary Siuzdak Scripps Research Institute
Emily Y. Chew
Emily Y. Chew National Institutes of Health
Rando Allikmets
Rando Allikmets Columbia University
Eyal Banin
Eyal Banin Hebrew University of Jerusalem
Melanie Bahlo
Melanie Bahlo Walter and Eliza Hall Institute of Medical Research
Glenn J. Jaffe
Glenn J. Jaffe Duke University
Lois E. H. Smith
Lois E. H. Smith Boston Children's Hospital
Paul Schimmel
Paul Schimmel Scripps Research Institute
Sina Farsiu
Sina Farsiu Duke University

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