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Ernst Bamberg

Ernst Bamberg

D-Index & Metrics

Chemistry

D-Index
86
Citations
24617
World Ranking
2570
National Ranking
192

Research.com Recognitions

  • 2013 - The Brain Prize, Lundbeck Foundation For their invention and refinement of optogenetics. This revolutionary technique allows genetically specified populations of neurons to be turned on or off with light, offering not only the ability to elucidate the characteristics of normal and abnormal neural circuitry but also new approaches to treatment of brain disorders

Overview

Ernst Bamberg is affiliated with the Max Planck Society in Germany and specializes in neuroscience, particularly cellular and molecular neuroscience. Their research spans molecular biology, biomedical engineering, spectroscopy, and plant science. The primary focus of their work centers on photoreceptor and optogenetics research as well as neuroscience and neuropharmacology.

The scientist's main topics of work include:

  • Photoreceptor and optogenetics research
  • Neuroscience and neuropharmacology research
  • Molecular communication and nanonetworks
  • Photosynthetic processes and mechanisms
  • Neural dynamics and brain function
  • Retinal development and disorders
  • Mass spectrometry techniques and applications

Ernst Bamberg has contributed to research published primarily in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Nature Structural & Molecular Biology
  • RWTH Publications (RWTH Aachen)
  • Proceedings of the National Academy of Sciences

Some of the recent papers include:

  • Molecular mechanism of light-driven sodium pumping, 2020, Nature Communications
  • High-resolution structural insights into the heliorhodopsin family, 2020, Proceedings of the National Academy of Sciences
  • Viral rhodopsins 1 are an unique family of light-gated cation channels, 2020, Nature Communications
  • Channelrhodopsin-mediated optogenetics highlights a central role of depolarization-dependent plant proton pumps, 2020, Proceedings of the National Academy of Sciences
  • True-atomic-resolution insights into the structure and functional role of linear chains and low-barrier hydrogen bonds in proteins, 2022, Nature Structural & Molecular Biology

Frequent collaborators include:

  • Valentin Gordeliy
  • Alexey Alekseev
  • Kirill Kovalev
  • Dmitrii Zabelskii
  • Roman Astashkin

Ernst Bamberg has been recognized with The Brain Prize from the Lundbeck Foundation in 2013 for contributions related to the invention and refinement of optogenetics, a technique that enables the targeted control of neurons with light. This method has implications for understanding neural circuitry and advancing treatments for brain disorders.

Best Publications

  • Millisecond-timescale, genetically targeted optical control of neural activity.

    Edward S Boyden;Feng Zhang;Ernst Bamberg;Georg Nagel

  • Channelrhodopsin-2, a directly light-gated cation-selective membrane channel.

    Georg Nagel;Tanjef Szellas;Wolfram Huhn;Suneel Kateriya

  • Multimodal fast optical interrogation of neural circuitry

    Feng Zhang;Li-Ping Wang;Martin Brauner;Jana F. Liewald

  • Channelrhodopsin-1: a light-gated proton channel in green algae.

    Georg Nagel;Doris Ollig;Markus Fuhrmann;Suneel Kateriya

  • Light Activation of Channelrhodopsin-2 in Excitable Cells of Caenorhabditis elegans Triggers Rapid Behavioral Responses

    Georg Nagel;Martin Brauner;Jana F. Liewald;Nona Adeishvili

  • Ultra light-sensitive and fast neuronal activation with the Ca2+-permeable channelrhodopsin CatCh

    Sonja Kleinlogel;Katrin Feldbauer;Robert E Dempski;Heike Fotis

  • Identification of synaptophysin as a hexameric channel protein of the synaptic vesicle membrane.

    Leo Thomas;Klaus Hartung;Dieter Langosch;Hubert Rehm

  • Channel formation kinetics of gramicidin A in lipid bilayer membranes.

    E Bamberg;P Läuger

  • Aspartic acids 96 and 85 play a central role in the function of bacteriorhodopsin as a proton pump.

    Hans-Jürgen Butt;Klaus Fendler;Ernst Bamberg;Jörg Tittor

  • Scan speed limit in atomic force microscopy

    Hans-Jürgen Butt;Peter Siedle;Karsten Seifert;Klaus Fendler

  • Spectral Characteristics of the Photocycle of Channelrhodopsin-2 and Its Implication for Channel Function

    Christian Bamann;Taryn Kirsch;Georg Nagel;Ernst Bamberg

  • Structural Guidance of the Photocycle of Channelrhodopsin-2 by an Interhelical Hydrogen Bond

    Christian Bamann;Ronnie Gueta;Sonja Kleinlogel;Georg Nagel

  • Channelrhodopsin-2 is a leaky proton pump

    Katrin Feldbauer;Dirk Zimmermann;Verena Pintschovius;Julia Spitz

  • Proteorhodopsin is a light-driven proton pump with variable vectoriality.

    Thomas Friedrich;Sven Geibel;Rolf Kalmbach;Igor Chizhov

  • A unifying concept for ion translocation by retinal proteins.

    Dieter Oesterhelt;Jörg Tittor;Ernst Bamberg

  • Phloem-localized, Proton-coupled Sucrose Carrier ZmSUT1 Mediates Sucrose Efflux under the Control of the Sucrose Gradient and the Proton Motive Force

    Armando Carpaneto;Dietmar Geiger;Ernst Bamberg;Norbert Sauer

  • A defective proton pump, point-mutated bacteriorhodopsin Asp96----Asn is fully reactivated by azide.

    Jörg Tittor;Christa Soell;Dieter Oesterhelt;Hans J. Butt

  • Relaxation studies of ion transport systems in lipid bilayer membranes.

    P. Läuger;R. Benz;G. Stark;E. Bamberg

  • Light-driven proton or chloride pumping by halorhodopsin.

    Ernst Bamberg;Jörg Tittor;Dieter Oesterhelt

  • Structural insights into ion conduction by channelrhodopsin 2

    Oleksandr Volkov;Kirill Kovalev;Vitaly Polovinkin;Valentin Borshchevskiy

  • Targeting Channelrhodopsin-2 to ON-bipolar Cells With Vitreally Administered AAV Restores ON and OFF Visual Responses in Blind Mice

    Emilie Macé;Emilie Macé;Emilie Macé;Romain Caplette;Romain Caplette;Romain Caplette;Olivier Marre;Olivier Marre;Olivier Marre;Abhishek Sengupta;Abhishek Sengupta;Abhishek Sengupta

  • General Concept for Ion Translocation by Halobacterial Retinal Proteins: The Isomerization/Switch/Transfer (IST) Model

    Ulrich Haupts;Jörg Tittor;Ernst Bamberg;Dieter Oesterhelt

Frequent Co-Authors

Peter Hegemann
Peter Hegemann Humboldt-Universität zu Berlin
Dieter Oesterhelt
Dieter Oesterhelt Max Planck Society
Hans-Jürgen Butt
Hans-Jürgen Butt Max Planck Society
Joachim Heberle
Joachim Heberle Freie Universität Berlin
Ulrich Zimmermann
Ulrich Zimmermann University of Würzburg
Martin Engelhard
Martin Engelhard Max Planck Society
Josef Wachtveitl
Josef Wachtveitl Goethe University Frankfurt
Francisco Rodriguez-Valera
Francisco Rodriguez-Valera Miguel Hernandez University
Tobias Moser
Tobias Moser University of Göttingen
Botond Roska
Botond Roska University of Basel

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