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Biology and Biochemistry

D-Index
73
Citations
21632
World Ranking
5878
National Ranking
2782

Research.com Recognitions

  • 2007 - Fellow of the American Academy of Arts and Sciences

Overview

John L. Spudich is affiliated with The University of Texas Health Science Center at Houston in the United States. Their research spans multiple areas within neuroscience and molecular biology, focusing primarily on the study of photoreceptors and optogenetics.

Spudich has authored numerous publications, particularly in the fields of Neuroscience and Biochemistry, Genetics and Molecular Biology. Their work often intersects with Cellular and Molecular Neuroscience, Molecular Biology, Biomedical Engineering, Cognitive Neuroscience, and Plant Science.

The main topics that Spudich has explored include:

  • Photoreceptor and optogenetics research
  • Neuroscience and Neuropharmacology Research
  • Bioluminescence and chemiluminescence research
  • Molecular Communication and Nanonetworks
  • Neural dynamics and brain function
  • Plant and Biological Electrophysiology Studies
  • Nicotinic Acetylcholine Receptors Study

Frequent co-authors collaborating with Spudich are:

  • Elena G. Govorunova
  • Oleg A. Sineshchekov
  • Hai Li
  • Leonid S. Brown
  • Yumei Wang

Common venues for Spudich's publications include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • eLife
  • mBio
  • Proceedings of the National Academy of Sciences
  • Nature Communications

Among their recent papers are:

  • "Kalium channelrhodopsins are natural light-gated potassium channels that mediate optogenetic inhibition," 2022, Nature Neuroscience
  • "An Open Resource for Non-human Primate Optogenetics," 2020, Neuron
  • "RubyACRs, nonalgal anion channelrhodopsins with highly red-shifted absorption," 2020, Proceedings of the National Academy of Sciences
  • "Emerging Diversity of Channelrhodopsins and Their Structure-Function Relationships," 2022, Frontiers in Cellular Neuroscience
  • "Cation and Anion Channelrhodopsins: Sequence Motifs and Taxonomic Distribution," 2021, mBio

In 2007, Spudich was awarded the title of Fellow of the American Academy of Arts and Sciences.

Best Publications

  • Bacterial Rhodopsin: Evidence for a New Type of Phototrophy in the Sea

    Oded Béjà;L. Aravind;Eugene V. Koonin;Marcelino T. Suzuki

  • Proteorhodopsin phototrophy in the ocean

    Oded Béjà;Elena N. Spudich;John L. Spudich;Marion Leclerc

  • Genome sequence of Halobacterium species NRC-1

    Wailap Victor Ng;Wailap Victor Ng;Sean P. Kennedy;Gregory G. Mahairas;Gregory G. Mahairas;Brian Berquist

  • Retinylidene Proteins: Structures and Functions from Archaea to Humans

    John L. Spudich;Chii-Shen Yang;Kwang-Hwan Jung;Elena N. Spudich

  • Natural light-gated anion channels: A family of microbial rhodopsins for advanced optogenetics

    Elena G. Govorunova;Oleg A. Sineshchekov;Roger Janz;Xiaoqin Liu

  • Two rhodopsins mediate phototaxis to low- and high-intensity light in Chlamydomonas reinhardtii.

    Oleg A. Sineshchekov;Kwang Hwan Jung;Kwang Hwan Jung;John L. Spudich

  • Non-genetic individuality: chance in the single cell

    John L. Spudich;D. E. Koshland

  • Crystal structure of sensory rhodopsin II at 2.4 angstroms: insights into color tuning and transducer interaction.

    Hartmut Luecke;Brigitte Schobert;Janos K. Lanyi;Elena N. Spudich

  • Identification of a third rhodopsin-like pigment in phototactic Halobacterium halobium.

    Roberto A. Bogomolni;John L. Spudich

  • MOLECULAR MECHANISM OF PHOTOSIGNALING BY ARCHAEAL SENSORY RHODOPSINS

    Wouter D. Hoff;Kwang Hwan Jung;John L. Spudich

  • Mechanism of colour discrimination by a bacterial sensory rhodopsin.

    John L. Spudich;Roberto A. Bogomolni

  • Diversification and spectral tuning in marine proteorhodopsins.

    Dikla Man;Weiwu Wang;Gazalah Sabehi;L. Aravind

  • Microbial Rhodopsins: Diversity, Mechanisms, and Optogenetic Applications

    Elena G Govorunova;Oleg A Sineshchekov;Hai Li;John L Spudich

  • Demonstration of a sensory rhodopsin in eubacteria.

    Kwang Hwan Jung;Vishwa D. Trivedi;John L Spudich

  • Handbook of Photosensory Receptors

    Winslow R. Briggs;John Lee Spudich

  • New insights into metabolic properties of marine bacteria encoding proteorhodopsins

    Gazalah Sabehi;Alexander Loy;Kwang Hwan Jung;Ranga Partha

  • Anabaena sensory rhodopsin: a photochromic color sensor at 2.0 A.

    Lutz Vogeley;Oleg A. Sineshchekov;Vishwa D. Trivedi;Jun Sasaki

  • Proton transfers in the photochemical reaction cycle of proteorhodopsin.

    Andrei K. Dioumaev;Leonid S. Brown;Jennifer Shih;Elena N. Spudich

  • Microbial rhodopsins: functional versatility and genetic mobility

    Adrian K. Sharma;John L. Spudich;W. Ford Doolittle

  • Regulation of the Chlamydomonas cell cycle by light and dark.

    John L. Spudich;Ruth Sager

Frequent Co-Authors

Kenneth J. Rothschild
Kenneth J. Rothschild Boston University
Hideki Kandori
Hideki Kandori Nagoya Institute of Technology
Oded Béjà
Oded Béjà Technion – Israel Institute of Technology
Koji Nakanishi
Koji Nakanishi Columbia University
Bing Yan
Bing Yan Griffith University
Janos K. Lanyi
Janos K. Lanyi University of California, Irvine
Masahide Terazima
Masahide Terazima Kyoto University
Ah-Lim Tsai
Ah-Lim Tsai The University of Texas at Austin
Gane Ka-Shu Wong
Gane Ka-Shu Wong University of Alberta
Leroy Hood
Leroy Hood University of Washington

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