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Kenneth J. Rothschild

Kenneth J. Rothschild

D-Index & Metrics

Chemistry

D-Index
68
Citations
12693
World Ranking
6717
National Ranking
2017

Research.com Recognitions

  • 2016 - Fellow, National Academy of Inventors
  • 1990 - Fellow of American Physical Society (APS) Citation For leadership in application of Raman and infraredspectroscopic techniques to biomembrane systems

Overview

Kenneth J. Rothschild is affiliated with Boston University in the United States. Their research spans several fields, focusing primarily on biochemistry, genetics, and molecular biology, with a secondary emphasis on chemistry. The scientist's work engages deeply with molecular biology and spectroscopy, as well as cellular and molecular neuroscience, biomedical engineering, and genetics.

Their main topics of research include mass spectrometry techniques and applications, molecular biology techniques and applications, advanced proteomics techniques and applications, photoreceptor and optogenetics research, glycosylation and glycoproteins research, RNA and protein synthesis mechanisms, and neuroscience and neuropharmacology research.

Some of the recent published papers by Rothschild include:

  • Highly Multiplexed Immunohistochemical MALDI-MS Imaging of Biomarkers in Tissues, 2021, Journal of the American Society for Mass Spectrometry
  • MALDI-IHC-Guided In-Depth Spatial Proteomics: Targeted and Untargeted MSI Combined, 2023, Analytical Chemistry
  • MALDI HiPLEX-IHC: multiomic and multimodal imaging of targeted intact proteins in tissues, 2023, Frontiers in Chemistry
  • Evaluation of antibody-based single cell type imaging techniques coupled to multiplexed imaging of N-glycans and collagen peptides by matrix-assisted laser desorption/ionization mass spectrometry imaging, 2023, Analytical and Bioanalytical Chemistry
  • Real-time glioblastoma tumor microenvironment assessment by SpiderMass for improved patient management, 2024, Cell Reports Medicine

Rothschild has coauthored frequently with several researchers including:

  • Gargey Yagnik
  • Mark J. Lim
  • Richard R. Drake
  • Peggi M. Angel
  • Ziying Liu

Their work has been published in prominent venues such as:

  • Cancer Research
  • Journal of the American Society for Mass Spectrometry
  • Analytical Chemistry
  • Frontiers in Chemistry
  • Analytical and Bioanalytical Chemistry

Kenneth J. Rothschild has received recognition as a Fellow of the National Academy of Inventors since 2016. Earlier, in 1990, they were named Fellow of the American Physical Society (APS) with a citation acknowledging their leadership in applying Raman and infrared spectroscopic techniques to biomembrane systems.

Best Publications

  • Vibrational spectroscopy of bacteriorhodopsin mutants: light-driven proton transport involves protonation changes of aspartic acid residues 85, 96, and 212

    Mark S. Braiman;Tatsushi M. Mogi;Thomas M. Marti;Lawrence J. Stern

  • FTIR difference spectroscopy of bacteriorhodopsin: toward a molecular model.

    Kenneth J. Rothschild

  • Fourier Transform Infrared Techniques for Probing Membrane Protein Structure

    Mark S. Braiman;Kenneth J. Rothschild

  • Spontaneous, pH-dependent membrane insertion of a transbilayer alpha-helix.

    John F. Hunt;Parshuram Rath;Kenneth J. Rothschild;Donald M. Engelman

  • Photocleavable agents and conjugates for the detection and isolation of biomolecules

    Kenneth J. Rothschild;Sanjay M. Sonar;Jerzy Olejnik

  • Polarized infrared spectroscopy of oriented purple membrane.

    K.J. Rothschild;N.A. Clark

  • Stabilization of the membrane protein bacteriorhodopsin to 140 °C in two-dimensional films

    Yi Shen;Cyrus R. Safinya;Keng S. Liang;A. F. Ruppert

  • Self-assembled nanometer lithographic masks and templates and method for parallel fabrication of nanometer scale multi-device structures

    Noel A. Clark;Kenneth Douglas;Kenneth J. Rothschild

  • Photocleavable biotin derivatives: a versatile approach for the isolation of biomolecules

    Jerzy Olejnik;Sanjay Sonar;Edyta Krzymanska-Olejnik;Kenneth J. Rothschild

  • A biophysical study of integral membrane protein folding.

    John F. Hunt;Thomas N. Earnest;Olaf Bousché;Krishna Kalghatgi

  • Protein dynamics in the bacteriorhodopsin photocycle: submillisecond Fourier transform infrared spectra of the L, M, and N photointermediates

    Mark S. Braiman;Olaf Bousche;Kenneth J. Rothschild

  • Surface-induced lamellar orientation of multilayer membrane arrays. Theoretical analysis and a new method with application to purple membrane fragments.

    N.A. Clark;K.J. Rothschild;D.A. Luippold;B.A. Simon

  • Conformational changes of bacteriorhodopsin detected by Fourier transform infrared difference spectroscopy

    Kenneth J. Rothschild;Mark Zagaeski;William A. Cantore

  • Method for parallel fabrication of nanometer scale multi-device structures

    Noel A. Clark;Kenneth Douglas;Kenneth J. Rothschild

  • Structural model of the phospholamban ion channel complex in phospholipid membranes.

    Isaiah T. Arkin;Matthew Rothman;Cheryl F.C. Ludlam;Saburo Aimoto

  • Infrared evidence that the Schiff base of bacteriorhodopsin is protonated: bR570 and K intermediates

    Kenneth J. Rothschild;Hector Marrero

  • Photocleavable Biotin Phosphoramidite for 5′-End-Labeling, Affinity Purification and Phosphorylation of Synthetic Oligonucleotides

    Jerzy Olejnik;Edyta Krzymanska-Olejnik;Kenneth J. Rothschild

  • Millisecond Fourier-transform infrared difference spectra of bacteriorhodopsin's M412 photoproduct.

    Mark S. Braiman;Patrick L. Ahl;Kenneth J. Rothschild

  • Cell-free co-expression of functional membrane proteins and apolipoprotein, forming soluble nanolipoprotein particles.

    Jenny A. Cappuccio;Craig D. Blanchette;Todd A. Sulchek;Erin S. Arroyo

  • Evidence for a tyrosine protonation change during the primary phototransition of bacteriorhodopsin at low temperature

    K J Rothschild;P Roepe;P L Ahl;T N Earnest

Frequent Co-Authors

John L. Spudich
John L. Spudich The University of Texas Health Science Center at Houston
Noel A. Clark
Noel A. Clark University of Colorado Boulder
Johan Lugtenburg
Johan Lugtenburg Leiden University
Paul D. Roepe
Paul D. Roepe Georgetown University
Judith Herzfeld
Judith Herzfeld Brandeis University
Lawrence J. Stern
Lawrence J. Stern University of Massachusetts Chan Medical School
Cyrus R. Safinya
Cyrus R. Safinya University of California, Santa Barbara
Donald M. Engelman
Donald M. Engelman Yale University

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