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Genetics

D-Index
42
Citations
14164
World Ranking
4303
National Ranking
1857

Overview

Mark D. Biggin is affiliated with the Lawrence Berkeley National Laboratory in the United States. Their research spans several interconnected areas within biological sciences, focusing primarily on biochemistry, genetics, and molecular biology.

Their scholarly output is concentrated in the fields of molecular biology and plant science, contributing to the broader disciplines of genomics, chromatin dynamics, developmental biology, gene regulation, and plant molecular biology research.

Biggin's work includes the publication titled Three-dimensional morphology and gene expression in the Drosophila blastoderm at cellular resolution II: dynamics, published in 2023 by OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information).

Their collaborations extend to several frequent co-authors, including:

  • Soile V.E. Keränen
  • Charless C. Fowlkes
  • Cris L. Luengo Hendriks
  • Damir Sudar
  • David Knowles

Biggin's publications have appeared in venues such as:

  • OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)

Their research topics primarily cover:

  • Genomics and Chromatin Dynamics
  • Developmental Biology and Gene Regulation
  • Plant Molecular Biology Research

Main fields of study emphasize:

  • Biochemistry, Genetics and Molecular Biology
  • Agricultural and Biological Sciences

Within these areas, their subfields of study include:

  • Molecular Biology
  • Plant Science

Best Publications

  • Buffer gradient gels and 35S label as an aid to rapid DNA sequence determination.

    M D Biggin;T J Gibson;G F Hong

  • DNA sequence and expression of the B95-8 Epstein—Barr virus genome

    R. Baer;R. Baer;A. T. Bankier;M. D. Biggin;P. L. Deininger

  • Genome-wide analysis of Polycomb targets in Drosophila melanogaster

    Yuri B. Schwartz;Tatyana G. Kahn;David A. Nix;David A. Nix;Xiao Yong Li

  • Transcription factors bind thousands of active and inactive regions in the Drosophila blastoderm.

    Xiao-yong Li;Stewart MacArthur;Richard Bourgon;David Nix

  • Transcription factors that activate the Ultrabithorax promoter in developmentally staged extracts.

    Mark D. Biggin;Robert Tjian

  • Developmental roles of 21 Drosophila transcription factors are determined by quantitative differences in binding to an overlapping set of thousands of genomic regions

    Stewart MacArthur;Stewart MacArthur;Xiao-Yong Li;Xiao-Yong Li;Jingyi Li;James B Brown

  • System wide analyses have underestimated protein abundances and the importance of transcription in mammals

    Jingyi Jessica Li;Peter J Bickel;Mark D Biggin

  • Animal transcription networks as highly connected, quantitative continua.

    Mark D. Biggin

  • A quantitative spatiotemporal atlas of gene expression in the Drosophila blastoderm.

    Charless C. Fowlkes;Cris L. Luengo Hendriks;Cris L. Luengo Hendriks;Soile V.E. Keränen;Soile V.E. Keränen;Gunther H. Weber;Gunther H. Weber

  • Large-scale turnover of functional transcription factor binding sites in Drosophila

    Alan M. Moses;Daniel A. Pollard;David A. Nix;Venky N. Iyer

  • NELF and GAGA Factor Are Linked to Promoter-Proximal Pausing at Many Genes in Drosophila†

    Chanhyo Lee;Xiaoyong Li;Aaron Hechmer;Michael Eisen;Michael Eisen

  • Association of cohesin and Nipped-B with transcriptionally active regions of the Drosophila melanogaster genome.

    Ziva Misulovin;Yuri B. Schwartz;Xiao-Yong Li;Tatyana G. Kahn

  • The role of chromatin accessibility in directing the widespread, overlapping patterns of Drosophila transcription factor binding.

    Xiao Yong Li;Xiao Yong Li;Sean Thomas;Peter J. Sabo;Michael B. Eisen;Michael B. Eisen

  • Binding Site Turnover Produces Pervasive Quantitative Changes in Transcription Factor Binding between Closely Related Drosophila Species

    Robert K. Bradley;Xiao-Yong Li;Xiao-Yong Li;Cole Trapnell;Stuart Davidson

  • Quantitative models of the mechanisms that control genome-wide patterns of transcription factor binding during early Drosophila development.

    Tommy Kaplan;Xiao Yong Li;Peter J. Sabo;Sean Thomas

  • Dynamic reprogramming of chromatin accessibility during Drosophila embryo development

    Sean Thomas;Xiao Yong Li;Peter J. Sabo;Richard Sandstrom

  • Statistics requantitates the central dogma

    Jingyi Jessica Li;Mark D. Biggin

  • Regulation of segmentation and segmental identity by Drosophila homeoproteins: the role of DNA binding in functional activity and specificity.

    Mark D. Biggin;William McGinnis

  • A purified Drosophila homeodomain protein represses transcription in vitro

    Mark D. Biggin;Robert Tjian

  • Epstein-Barr virus gene expression in P3HR1-superinfected Raji cells.

    M Biggin;M Bodescot;M Perricaudet;P Farrell

Frequent Co-Authors

Michael B. Eisen
Michael B. Eisen University of California, Berkeley
Bernd Hamann
Bernd Hamann University of California, Davis
Jitendra Malik
Jitendra Malik University of California, Berkeley
Terry C. Hazen
Terry C. Hazen University of Tennessee at Knoxville
Charless C. Fowlkes
Charless C. Fowlkes University of California, Irvine
Peter J. Bickel
Peter J. Bickel University of California, Berkeley
Susan J. Fisher
Susan J. Fisher University of California, San Francisco
Hans Hagen
Hans Hagen Technical University of Kaiserslautern
Susan E. Celniker
Susan E. Celniker Lawrence Berkeley National Laboratory
Steven E. Brenner
Steven E. Brenner University of California, Berkeley

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