2026 Lawrence J. Stern: Biology and Biochemistry Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Biology and Biochemistry	75	5289	4884	2512	2259	258	21327

Overview

Lawrence J. Stern is affiliated with the University of Massachusetts Chan Medical School in the United States. Their research spans multiple fields including Immunology and Microbiology, Medicine, and Biochemistry, Genetics and Molecular Biology. Within these domains, their work focuses particularly on Immunology, Molecular Biology, Epidemiology, Infectious Diseases, and Radiology, Nuclear Medicine and Imaging.

The scientist's recent significant publications include:

"Pleiotropic consequences of metabolic stress for the major histocompatibility complex class II molecule antigen processing and presentation machinery," 2021, Immunity
"PDIA3 epitope-driven immune autoreactivity contributes to hepatic damage in type 2 diabetes," 2022, Science Immunology
"Conformational dynamics linked to domain closure and substrate binding explain the ERAP1 allosteric regulation mechanism," 2021, Nature Communications
"Broadly recognized, cross-reactive SARS-CoV-2 CD4 T cell epitopes are highly conserved across human coronaviruses and presented by common HLA alleles," 2022, Cell Reports
"Non-mutational neoantigens in disease," 2024, Nature Immunology

The primary topics addressed in their research include:

Immunotherapy and Immune Responses
Vaccines and immunoinformatics approaches
Immune Cell Function and Interaction
T-cell and B-cell Immunology
SARS-CoV-2 and COVID-19 Research
Monoclonal and Polyclonal Antibodies Research
Diabetes and associated disorders

Frequent coauthors collaborating with the scientist are:

Padma P. Nanaware
Cristina C. Clement
Laura Santambrogio
Grant C. Weaver
Richa Arya

The scientist's publications are often found in the following venues:

The Journal of Immunology
Frontiers in Immunology
Molecular Immunology
Cell Reports
bioRxiv (Cold Spring Harbor Laboratory)

Best Publications

Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1

Jerry H. Brown;Theodore S. Jardetzky;Joan C. Gorga;Joan C. Gorga;Lawrence J. Stern;Lawrence J. Stern

3099
Citations
Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide

Lawrence J. Stern;Jerry H. Brown;Theodore S. Jardetzky;Joan C. Gorga

1960
Citations
Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in size

Roman M. Chicz;Robert G. Urban;William S. Lane;Joan C. Gorga;Joan C. Gorga

995
Citations
Three-dimensional structure of a human class II histocompatibility molecule complexed with superantigen.

Theodore S Jardetzky;Jerry H Brown;Jerry H Brown;Joan C Gorga;Lawrence J Stern

731
Citations
Vibrational spectroscopy of bacteriorhodopsin mutants: light-driven proton transport involves protonation changes of aspartic acid residues 85, 96, and 212

Mark S. Braiman;Tatsushi M. Mogi;Thomas M. Marti;Lawrence J. Stern

645
Citations
Antigenic peptide binding by class I and class II histocompatibility proteins

Lawrence J Stern;Don C Wiley

429
Citations
Proteomic Analysis of Microglia-Derived Exosomes: Metabolic Role of the Aminopeptidase CD13 in Neuropeptide Catabolism

Ilaria Potolicchio;Gregory J. Carven;Xiaonan Xu;Christopher Stipp

420
Citations
The human class II MHC protein HLA-DR1 assembles as empty αβ heterodimers in the absence of antigenic peptide

Lawrence J. Stern;Don C. Wiley;Don C. Wiley

412
Citations
Developmental plasticity of CNS microglia

L. Santambrogio;S. L. Belyanskaya;F. R. Fischer;B. Cipriani

367
Citations
Aspartic acid substitutions affect proton translocation by bacteriorhodopsin.

T Mogi;L J Stern;T Marti;B H Chao

357
Citations
Crystallographic analysis of endogenous peptides associated with HLA-DR1 suggests a common, polyproline II-like conformation for bound peptides

Theodore S. Jardetzky;Jerry H. Brown;Joan C. Gorga;Lawrence J. Stern

338
Citations
The relationship of MHC-peptide binding and T cell activation probed using chemically defined MHC class II oligomers.

Jennifer R Cochran;Thomas O Cameron;Lawrence J Stern

315
Citations
Phosphorylation of T cell receptor zeta is regulated by a lipid dependent folding transition.

Dikran Aivazian;Lawrence J. Stern

312
Citations
Substitution of amino acids Asp-85, Asp-212, and Arg-82 in bacteriorhodopsin affects the proton release phase of the pump and the pK of the Schiff base.

H Otto;T Marti;M Holz;T Mogi

304
Citations
Model studies of iron―tyrosinate proteins

Joseph W. Pyrz;A. Lawrence Roe;Lawrence J. Stern;Lawrence Que

295
Citations
Extracellular antigen processing and presentation by immature dendritic cells

Laura Santambrogio;Aaron K. Sato;Gregory J. Carven;Svetlana L. Belyanskaya

273
Citations
Peptide immunotherapy in allergic asthma generates IL-10–dependent immunological tolerance associated with linked epitope suppression

John D M Campbell;Karen F. Buckland;Sarah J. McMillan;Jennifer Kearley

261
Citations
Structural Basis For Antigenic Peptide Precursor Processing by the Endoplasmic Reticulum Aminopeptidase ERAP1

Tina T Nguyen;Shih‐Chung Chang;Irini Evnouchidou;Ian York

228
Citations
Binary and ternary complexes between T-cell receptor, class II MHC and superantigen in vitro

Alpna Seth;Lawrence J. Stern;Tom H. M. Ottenhoff;Isaac Engel;Isaac Engel

224
Citations
The class II MHC protein HLA-DR1 in complex with an endogenous peptide: implications for the structural basis of the specificity of peptide binding.

Venkatesh L Murthy;Lawrence J Stern

219
Citations