What is he best known for?
The fields of study he is best known for:
The scientist’s investigation covers issues in Peptide, Protein structure, Stereochemistry, MHC restriction and Biochemistry.
His Peptide course of study focuses on Biophysics and Halobacterium.
His work carried out in the field of Protein structure brings together such families of science as Peptide sequence, Conformational change, Binding site and Protein folding.
His study in Stereochemistry is interdisciplinary in nature, drawing from both Amino acid, Glycine, Chromophore, Proton transport and Histocompatibility.
His Histocompatibility research is multidisciplinary, incorporating perspectives in Dimer, Glycoprotein and HLA-DR1.
His HLA-DM research is within the category of Antigen.
His most cited work include:
- Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1 (2077 citations)
- Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1 (2077 citations)
- Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide (1377 citations)
What are the main themes of his work throughout his whole career to date?
His primary scientific interests are in Major histocompatibility complex, Peptide, Biochemistry, Antigen and Stereochemistry.
His Major histocompatibility complex study incorporates themes from Epitope, T cell, Antigen presentation and Cell biology.
His T cell research is multidisciplinary, incorporating elements of Cytotoxic T cell and CD8.
His research on Peptide also deals with topics like
- HLA-DM which intersects with area such as HLA-DO,
- Peptide binding and related Plasma protein binding.
His study in Histocompatibility, Human leukocyte antigen and HLA-DR1 are all subfields of Antigen.
His Stereochemistry study combines topics in areas such as Amino acid, Polyproline helix, Crystallography, Bacteriorhodopsin and Dimer.
He most often published in these fields:
- Major histocompatibility complex (34.83%)
- Peptide (30.85%)
- Biochemistry (25.37%)
What were the highlights of his more recent work (between 2016-2021)?
- Epitope (19.40%)
- T-cell receptor (13.93%)
- Cell biology (18.41%)
In recent papers he was focusing on the following fields of study:
His primary scientific interests are in Epitope, T-cell receptor, Cell biology, Antigen presentation and Antigen.
His Antigen presentation research includes elements of Plasma protein binding, Autoimmunity, Major histocompatibility complex and Peptide.
His study looks at the relationship between Major histocompatibility complex and fields such as Cytotoxic T cell, as well as how they intersect with chemical problems.
His Peptide research is multidisciplinary, relying on both Amino acid, Aminopeptidase, MHC class I and Peptide binding.
Lawrence J. Stern has included themes like Stereochemistry and Enzyme in his Aminopeptidase study.
His Antigen research focuses on Human leukocyte antigen and Peripheral tolerance.
Between 2016 and 2021, his most popular works were:
- Broad TCR repertoire and diverse structural solutions for recognition of an immunodominant CD8(+) T cell epitope. (41 citations)
- Class II MHC antigen processing in immune tolerance and inflammation. (25 citations)
- Shigella depends on SepA to destabilize the intestinal epithelial integrity via cofilin activation (18 citations)
In his most recent research, the most cited papers focused on:
Lawrence J. Stern focuses on Epitope, Immune system, Immunology, Antigen and Antigen presentation.
His research in Epitope intersects with topics in T cell, T-cell receptor, Conformational change, Biochemistry and Cytotoxic T cell.
Lawrence J. Stern interconnects Metabolite, Albumin, Hapten and Neuroinflammation in the investigation of issues within Immune system.
His Antigen study frequently draws connections to other fields, such as Autoimmunity.
The study incorporates disciplines such as Major histocompatibility complex and Peptide in addition to Antigen presentation.
The Peptide study combines topics in areas such as Aminopeptidase, MHC class I and Cancer immunotherapy.
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