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Marc Fransen

Marc Fransen

D-Index & Metrics

Biology and Biochemistry

D-Index
50
Citations
17633
World Ranking
17414
National Ranking
290

Overview

Marc Fransen is a researcher affiliated with KU Leuven in Belgium, with a scholarly focus primarily in Biochemistry, Genetics, and Molecular Biology. Their publication profile includes significant work in subfields such as Molecular Biology, Physiology, Epidemiology, Cancer Research, and Electrical and Electronic Engineering.

The scientist's research primarily addresses topics including:

  • Peroxisome Proliferator-Activated Receptors
  • Adenosine and Purinergic Signaling
  • Autophagy in Disease and Therapy
  • Redox biology and oxidative stress
  • Fuel Cells and Related Materials
  • RNA modifications and cancer
  • Biomedical Research and Pathophysiology

Marc Fransen has contributed to several recent papers, reflecting an interest in cellular processes, organelle communication, and biochemistry. Notable recent publications include:

  • "Mitochondrial fission factor (MFF) is a critical regulator of peroxisome maturation", 2020, published in Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  • "The Peroxisome-Autophagy Redox Connection: A Double-Edged Sword?", 2021, published in Frontiers in Cell and Developmental Biology
  • "Slc25a17 Gene Trapped Mice: PMP34 Plays a Role in the Peroxisomal Degradation of Phytanic and Pristanic Acid", 2020, published in Frontiers in Cell and Developmental Biology
  • "Peroxisomal hydrogen peroxide signaling: A new chapter in intracellular communication research", 2024, published in Current Opinion in Chemical Biology
  • "The murine retinal pigment epithelium requires peroxisomal β-oxidation to maintain lysosomal function and prevent dedifferentiation", 2023, published in Proceedings of the National Academy of Sciences

The scientist frequently collaborates with a core group of coauthors, including Celien Lismont, Cláudio F. Costa, Mohamed A. F. Hussein, Hongli Li, and Paul P. Van Veldhoven. These collaborations have produced a body of work contributing notably to cellular and molecular biology, with particular attention to peroxisomal function and signaling pathways.

Marc Fransen's research outputs have appeared repeatedly in journals such as Free Radical Biology and Medicine, bioRxiv (Cold Spring Harbor Laboratory), Frontiers in Cell and Developmental Biology, Antioxidants, and Methods in Molecular Biology. This range shows engagement with both experimental and review literature formats across related fields.

In addition to peer-reviewed articles, Marc Fransen has contributed to book publications, including a volume titled "Molecular Mechanisms and Physiological Significance of Organelle Interactions and Cooperation - Volume II" published by Frontiers Media in 2022.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Peroxisomes are signaling platforms for antiviral innate immunity

    Evelyn Dixit;Steeve Boulant;Yijing Zhang;Amy S.Y. Lee

  • Role of peroxisomes in ROS/RNS-metabolism: implications for human disease.

    Marc Fransen;Marcus Nordgren;Bo Wang;Oksana Apanasets

  • A mouse model for Zellweger syndrome.

    M Baes;P Gressens;E Baumgart;P Carmeliet

  • The Peroxisome-Mitochondria Connection: How and Why?

    Marc Fransen;Celien Lismont;Paul A Walton

  • The Difference in Recognition of Terminal Tripeptides as Peroxisomal Targeting Signal 1 between Yeast and Human Is Due to Different Affinities of Their Receptor Pex5p to the Cognate Signal and to Residues Adjacent to It

    Guenther Lametschwandtner;Cécile Brocard;Marc Fransen;Paul Van Veldhoven

  • Identification and Characterization of the Putative Human Peroxisomal C-terminal Targeting Signal Import Receptor

    Marc Fransen;Chantal Brees;Eveline Baumgart;Johannes C.T. Vanhooren

  • Intraperoxisomal redox balance in mammalian cells: oxidative stress and interorganellar cross-talk

    Oksana Ivashchenko;Paul P. Van Veldhoven;Chantal Brees;Ye Shih Ho

  • The CoA esters of 2-methyl-branched chain fatty acids and of the bile acid intermediates di- and trihydroxycoprostanic acids are oxidized by one single peroxisomal branched chain acyl-CoA oxidase in human liver and kidney

    G. F. Vanhove;P. P. Van Veldhoven;M. Fransen;S. Denis

  • IDENTIFICATION OF A HUMAN PTS1 RECEPTOR DOCKING PROTEIN DIRECTLY REQUIRED FOR PEROXISOMAL PROTEIN IMPORT

    Marc Fransen;Stanley R. Terlecky;Suresh Subramani

  • Peroxisome dynamics in cultured mammalian cells.

    Sofie J. Huybrechts;Paul P. Van Veldhoven;Chantal Brees;Guy P. Mannaerts

  • Ubiquitination of mammalian Pex5p, the peroxisomal import receptor.

    Andreia F. Carvalho;Manuel P. Pinto;Manuel P. Pinto;Cláudia P. Grou;Cláudia P. Grou;Inês S. Alencastre;Inês S. Alencastre

  • Peroxisomal metabolism and oxidative stress.

    Marcus Nordgren;Marc Fransen

  • Human Pex19p Binds Peroxisomal Integral Membrane Proteins at Regions Distinct from Their Sorting Sequences

    Marc Fransen;Tine Wylin;Chantal Brees;Guy P. Mannaerts

  • Further characterization of the peroxisomal 3-hydroxyacyl-CoA dehydrogenases from rat liver. Relationship between the different dehydrogenases and evidence that fatty acids and the C27 bile acids di- and tri-hydroxycoprostanic acids are metabolized by separate multifunctional proteins.

    Martine Dieuaide-Noubhani;Dmitry Novikov;Eveline Baumgart;Johannes C. T. Vanhooren

  • Redox interplay between mitochondria and peroxisomes

    Celien Lismont;Marcus Nordgren;Paul P. Van Veldhoven;Marc Fransen

  • Peroxisomal Hydrogen Peroxide Metabolism and Signaling in Health and Disease

    Celien Lismont;Iulia Revenco;Marc Fransen

  • Import of peroxisomal membrane proteins: the interplay of Pex3p- and Pex19p-mediated interactions.

    Yukio Fujiki;Yuji Matsuzono;Takashi Matsuzaki;Marc Fransen

  • Mitochondria are targets for peroxisome-derived oxidative stress in cultured mammalian cells

    Bo Wang;Paul P Van Veldhoven;Chantal Brees;N Rubio

  • Molecular characterization of the human peroxisomal branched-chain acyl-CoA oxidase: cDNA cloning, chromosomal assignment, tissue distribution, and evidence for the absence of the protein in Zellweger syndrome.

    Eveline Baumgart;Johannes C. T. Vanhooren;Mark Fransen;Peter Marynen

Frequent Co-Authors

Myriam Baes
Myriam Baes KU Leuven
Stephen G. Young
Stephen G. Young University of California, Los Angeles
Suresh Subramani
Suresh Subramani University of California, San Diego
Michael Schrader
Michael Schrader University of Exeter
Pedro Domingues
Pedro Domingues University of Aveiro
Andrea Ballabio
Andrea Ballabio Baylor College of Medicine
Enza Maria Valente
Enza Maria Valente University of Pavia

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