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Paul P. Van Veldhoven

Paul P. Van Veldhoven

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Biology and Biochemistry
Belgium
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
83
Citations
22588
World Ranking
3542
National Ranking
59

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Belgium Leader Award

Overview

Paul P. Van Veldhoven is affiliated with KU Leuven in Belgium and has a research profile concentrated in biochemistry, genetics, and molecular biology, with additional contributions in medicine. Their work primarily spans molecular biology, physiology, and cell biology, as well as clinical biochemistry and ophthalmology.

The scientist's research explores several main topics, including:

  • Peroxisome Proliferator-Activated Receptors
  • Adipose Tissue and Metabolism
  • Retinoids in leukemia and cellular processes
  • Lysosomal Storage Disorders Research
  • Metabolism and Genetic Disorders
  • Retinal Diseases and Treatments
  • Adenosine and Purinergic Signaling

Frequent co-authors contributing to multiple shared publications include:

  • Marc Fransen
  • Myriam Baes
  • Daniëlle Swinkels
  • Sai Kocherlakota
  • Cláudio F. Costa

The scientist's work has appeared repeatedly in a variety of publication venues, including:

  • Frontiers in Cell and Developmental Biology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Methods in molecular biology
  • Critical Care
  • Proceedings of the National Academy of Sciences

Notable recent papers authored or co-authored by Paul P. Van Veldhoven include:

  • Sphingosine-1-Phosphate Lyase 1, 2020, published in Definitions
  • Slc25a17 Gene Trapped Mice: PMP34 Plays a Role in the Peroxisomal Degradation of Phytanic and Pristanic Acid, 2020, published in Frontiers in Cell and Developmental Biology
  • Altered cholesterol homeostasis in critical illness-induced muscle weakness: effect of exogenous 3-hydroxybutyrate, 2021, published in Critical Care
  • Peroxisomal Multifunctional Protein 2 Deficiency Perturbs Lipid Homeostasis in the Retina and Causes Visual Dysfunction in Mice, 2021, published in Frontiers in Cell and Developmental Biology
  • The murine retinal pigment epithelium requires peroxisomal β-oxidation to maintain lysosomal function and prevent dedifferentiation, 2023, published in Proceedings of the National Academy of Sciences

Best Publications

  • Role of PFKFB3-Driven Glycolysis in Vessel Sprouting

    Katrien De Bock;Maria Georgiadou;Sandra Schoors;Anna Kuchnio

  • Loss of HIF-2α and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice

    Veerle Compernolle;Koen Brusselmans;Till Acker;Peter Hoet

  • Inorganic and organic phosphate measurements in the nanomolar range.

    Paul P. Van Veldhoven;Guy P. Mannaerts

  • De novo Lipogenesis Protects Cancer Cells from Free Radicals and Chemotherapeutics by Promoting Membrane Lipid Saturation

    Evelien Rysman;Koen Brusselmans;Katryn Scheys;Leen Timmermans

  • Fatty acid carbon is essential for dNTP synthesis in endothelial cells

    Sandra Schoors;Ulrike Bruning;Rindert Missiaen;Karla C S Queiroz

  • Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism

    Julián Aragonés;Martin Schneider;Martin Schneider;Martin Schneider;Katie Van Geyte;Katie Van Geyte;Peter Fraisl;Peter Fraisl

  • A unified nomenclature for peroxisome biogenesis factors.

    B. Distel;R. Erdmann;S. J. Gould;G. Blobel

  • Histamine Receptor H1-Mediated Sensitization of TRPV1 Mediates Visceral Hypersensitivity and Symptoms in Patients With Irritable Bowel Syndrome

    Mira M. Wouters;Dafne Balemans;Sander Van Wanrooy;James Dooley

  • Biochemistry and genetics of inherited disorders of peroxisomal fatty acid metabolism

    Paul P. Van Veldhoven

  • Fatty acid synthase drives the synthesis of phospholipids partitioning into detergent-resistant membrane microdomains

    Johannes V Swinnen;Paul P Van Veldhoven;Leen Timmermans;Ellen De Schrijver

  • Sphingosylphosphorylcholine regulates keratin network architecture and visco-elastic properties of human cancer cells

    Michael Beil;Alexandre Micoulet;Götz von Wichert;Stephan Paschke

  • The Difference in Recognition of Terminal Tripeptides as Peroxisomal Targeting Signal 1 between Yeast and Human Is Due to Different Affinities of Their Receptor Pex5p to the Cognate Signal and to Residues Adjacent to It

    Guenther Lametschwandtner;Cécile Brocard;Marc Fransen;Paul Van Veldhoven

  • Adenovirus-mediated gene transfer of human platelet-activating factor-acetylhydrolase prevents injury-induced neointima formation and reduces spontaneous atherosclerosis in apolipoprotein E-deficient mice.

    Rozenn Quarck;Bart De Geest;Dominique Stengel;Ann Mertens

  • Inactivation of the Peroxisomal Multifunctional Protein-2 in Mice Impedes the Degradation of Not Only 2-Methyl-branched Fatty Acids and Bile Acid Intermediates but Also of Very Long Chain Fatty Acids

    Myriam Baes;Steven Huyghe;Peter Carmeliet;Peter E. Declercq

  • Identification and Characterization of the Putative Human Peroxisomal C-terminal Targeting Signal Import Receptor

    Marc Fransen;Chantal Brees;Eveline Baumgart;Johannes C.T. Vanhooren

  • Intraperoxisomal redox balance in mammalian cells: oxidative stress and interorganellar cross-talk

    Oksana Ivashchenko;Paul P. Van Veldhoven;Chantal Brees;Ye Shih Ho

  • Absence of peroxisomes in mouse hepatocytes causes mitochondrial and ER abnormalities.

    Ruud Dirkx;Ilse Vanhorebeek;Katrin Martens;Arno Schad

  • Subcellular localization and membrane topology of sphingosine-1-phosphate lyase in rat liver.

    P.P. Van Veldhoven;G.P. Mannaerts

  • Substrate specificities of 3-oxoacyl-CoA thiolase A and sterol carrier protein 2/3-oxoacyl-CoA thiolase purified from normal rat liver peroxisomes - Sterol carrier protein 2/3-oxoacyl-CoA thiolase is involved in the metabolism of 2-methyl-branched fatty acids and bile acid intermediates

    Vasily D. Antonenkov;Paul P. Van Veldhoven;Etienne Waelkens;Guy P. Mannaerts

  • Peroxisome dynamics in cultured mammalian cells.

    Sofie J. Huybrechts;Paul P. Van Veldhoven;Chantal Brees;Guy P. Mannaerts

Frequent Co-Authors

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