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Molecular Biology

D-Index
55
Citations
15482
World Ranking
2251
National Ranking
1111

Overview

Joel G. Belasco is affiliated with New York University in the United States and has contributed extensively to the field of Biochemistry, Genetics, and Molecular Biology. Their research predominantly focuses on Molecular Biology, Genetics, and related subfields including Ecology, Aging, and Materials Chemistry.

The scientist's work centers on several key topics:

  • RNA and protein synthesis mechanisms
  • Bacterial Genetics and Biotechnology
  • RNA modifications and cancer
  • Genetics, Aging, and Longevity in Model Organisms
  • Enzyme Structure and Function
  • RNA Research and Splicing
  • CRISPR and Genetic Engineering

Joel G. Belasco has published research in various established scientific venues, showing a concentration in leading journals:

  • Proceedings of the National Academy of Sciences
  • Nucleic Acids Research
  • Nature Chemical Biology
  • Molecular Microbiology
  • Molecular Cell

Some of their recent significant papers include:

  • "Np 4 A alarmones function in bacteria as precursors to RNA caps" (2020, Proceedings of the National Academy of Sciences)
  • "Riboswitch control of bacterial RNA stability" (2021, Molecular Microbiology)
  • "Widespread Protection of RNA Cleavage Sites by a Riboswitch Aptamer that Folds as a Compact Obstacle to Scanning by RNase E" (2020, Molecular Cell)
  • "Graded impact of obstacle size on scanning by RNase E" (2023, Nucleic Acids Research)
  • "A distinct RNA recognition mechanism governs Np 4 decapping by RppH" (2022, Proceedings of the National Academy of Sciences)

Belasco frequently collaborates with several researchers, including:

  • D Luciano
  • Jamie Richards
  • Alexander Serganov
  • Rose Levenson-Palmer
  • Ashok Nuthanakanti

Best Publications

  • MicroRNAs direct rapid deadenylation of mRNA.

    Ligang Wu;Jihua Fan;Joel G. Belasco

  • The nonamer UUAUUUAUU is the key AU-rich sequence motif that mediates mRNA degradation.

    A M Zubiaga;J G Belasco;M E Greenberg

  • The c-fos transcript is targeted for rapid decay by two distinct mRNA degradation pathways.

    Ann-Bin Shyu;M. E. Greenberg;J. G. Belasco

  • Two distinct destabilizing elements in the c-fos message trigger deadenylation as a first step in rapid mRNA decay.

    Ann-Bin Shyu;Joel G. Belasco;Michael E. Greenberg

  • Let Me Count the Ways: Mechanisms of Gene Regulation by miRNAs and siRNAs

    Ligang Wu;Joel G. Belasco

  • The bacterial enzyme RppH triggers messenger RNA degradation by 5′ pyrophosphate removal

    Atilio Deana;Helena Celesnik;Joel G. Belasco

  • Decay of mRNA in Escherichia coli: investigation of the fate of specific segments of transcripts.

    A von Gabain;J G Belasco;J L Schottel;A C Chang

  • Lost in translation: the influence of ribosomes on bacterial mRNA decay

    Atilio Deana;Joel G. Belasco

  • A 5'-terminal stem-loop structure can stabilize mRNA in Escherichia coli.

    Sheri A. Emory;Philippe Bouvet;Joel G. Belasco

  • Mechanisms of mRNA decay in bacteria: a perspective

    Joel G. Belasco;Christopher F. Biggins

  • Micro-RNA Regulation of the Mammalian lin-28 Gene during Neuronal Differentiation of Embryonal Carcinoma Cells

    Ligang Wu;Joel G. Belasco

  • Differential expression of photosynthesis genes in R. capsulata results from segmental differences in stability within the polycistronic rxcA transcript.

    Joel G. Belasco;J.Thomas Beatty;Camellia W. Adams;Alexander von Gabain

  • Initiation of RNA decay in Escherichia coli by 5’ pyrophosphate removal

    Helena Celesnik;Atilio Deana;Joel G. Belasco

  • Growth-rate dependent regulation of mRNA stability in Escherichia coli

    G. Nilsson;J. G. Belasco;S. N. Cohen;A. von Gabain

  • Control of RNase E-mediated RNA degradation by 5'-terminal base pairing in E. coli.

    Philippe Bouvet;Philippe Bouvet;Joel G. Belasco

  • Messenger RNA degradation in bacterial cells.

    Monica P. Hui;Patricia L. Foley;Joel G. Belasco

  • beta-Lactamase proceeds via an acyl-enzyme intermediate. Interaction of the Escherichia coli RTEM enzyme with cefoxitin.

    Jed Fisher;Joel G. Belasco;Sundeep Khosla;Jeremy R. Knowles

  • The stability of E. coli gene transcripts is dependent on determinants localized to specific mRNA segments

    Joel G. Belasco;Gisela Nilsson;Alexander von Gabain;Alexander von Gabain;Stanley N. Cohen

  • T7 phage display: A novel genetic selection system for cloning RNA-binding proteins from cDNA libraries

    Stefan Danner;Joel G. Belasco

  • The ompA 5' untranslated RNA segment functions in Escherichia coli as a growth-rate-regulated mRNA stabilizer whose activity is unrelated to translational efficiency.

    S A Emory;J G Belasco

Frequent Co-Authors

Jeremy R. Knowles
Jeremy R. Knowles Harvard University
Michael E. Greenberg
Michael E. Greenberg Harvard University
Stanley N. Cohen
Stanley N. Cohen Stanford University
Ann-Bin Shyu
Ann-Bin Shyu The University of Texas Health Science Center at Houston
Philippe Bouvet
Philippe Bouvet École Normale Supérieure de Lyon
Sundeep Khosla
Sundeep Khosla Mayo Clinic
Phillip D. Zamore
Phillip D. Zamore University of Massachusetts Chan Medical School
Susan Gottesman
Susan Gottesman National Institutes of Health
Jörg Vogel
Jörg Vogel University of Würzburg
Cynthia M. Sharma
Cynthia M. Sharma University of Würzburg

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