World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
65
Citations
17231
World Ranking
9066
National Ranking
4029

Research.com Recognitions

  • 2011 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Henrik G. Dohlman is affiliated with the University of North Carolina at Chapel Hill in the United States. Their research primarily spans the field of Biochemistry, Genetics and Molecular Biology with a significant focus on Molecular Biology. Additional subfields include Cell Biology, Genetics, Biomedical Engineering, and Biochemistry.

The scientist's work covers a range of topics including:

  • Fungal and yeast genetics research
  • Protein Kinase Regulation and GTPase Signaling
  • Receptor Mechanisms and Signaling
  • Bioinformatics and Genomic Networks
  • Cellular transport and secretion
  • Microbial Metabolic Engineering and Bioproduction
  • Gene Regulatory Network Analysis

Recent notable publications by Henrik G. Dohlman include:

  • A universal allosteric mechanism for G protein activation, 2021, Molecular Cell
  • Molecular annotation of G protein variants in a neurological disorder, 2023, Cell Reports
  • Multi-omics analysis of glucose-mediated signaling by a moonlighting Gβ protein Asc1/RACK1, 2021, PLoS Genetics
  • Catalytic site mutations confer multiple states of G protein activation, 2023, Science Signaling
  • Potassium starvation induces autophagy in yeast, 2020, Journal of Biological Chemistry

Frequent publication venues for their work include:

  • UNC Libraries
  • Journal of Biological Chemistry
  • bioRxiv (Cold Spring Harbor Laboratory)
  • OPAL (Open@LaTrobe) (La Trobe University)
  • Cell Reports

Henrik G. Dohlman has collaborated regularly with several co-authors, among them:

  • Lila M. Gierasch
  • F. Peter Guengerich
  • Ruma Banerjee
  • Roger Colbran
  • Peter Cresswell

In 2011, Henrik G. Dohlman was recognized as a Fellow of the American Association for the Advancement of Science (AAAS).

Best Publications

  • Model systems for the study of seven-transmembrane-segment receptors.

    Henrik G. Dohlman;Jeremy Thorner;Marc G. Caron;Robert J. Lefkowitz

  • Cloning of the gene and cDNA for mammalian β -adrenergic receptor and homology with rhodopsin

    Richard A. F. Dixon;Brian K. Kobilka;David J. Strader;Jeffrey L. Benovic

  • cDNA for the human beta 2-adrenergic receptor: a protein with multiple membrane-spanning domains and encoded by a gene whose chromosomal location is shared with that of the receptor for platelet-derived growth factor.

    Brian K. Kobilka;Richard A. F. Dixon;Thomas Frielle;Henrik G. Dohlman

  • A family of receptors coupled to guanine nucleotide regulatory proteins.

    Henrik G. Dohlman;Marc G. Caron;Robert J. Lefkowitz

  • RGS Proteins and Signaling by Heterotrimeric G Proteins

    Henrik G. Dohlman;Jeremy Thorner

  • Regulation of G Protein–Initiated Signal Transduction in Yeast: Paradigms and Principles

    Henrik G. Dohlman;Jeremy W. Thorner

  • Regulators of G-Protein Signaling (RGS) Proteins: Region-Specific Expression of Nine Subtypes in Rat Brain

    Stephen J. Gold;Yan G. Ni;Henrik G. Dohlman;Eric J. Nestler

  • Sst2, a negative regulator of pheromone signaling in the yeast Saccharomyces cerevisiae: expression, localization, and genetic interaction and physical association with Gpa1 (the G-protein alpha subunit).

    Henrik G. Dohlman;Jianping Song;Doreen Ma;William E. Courchesne

  • The experimental power of FR900359 to study Gq-regulated biological processes

    Ramona Schrage;Anna Lena Schmitz;Evelyn Gaffal;Suvi Annala

  • Control of yeast mating signal transduction by a mammalian beta 2-adrenergic receptor and Gs alpha subunit

    Klim King;Henrik G. Dohlman;Jeremy Thorner;Marc G. Caron

  • Delineation of the intronless nature of the genes for the human and hamster beta 2-adrenergic receptor and their putative promoter regions.

    B K Kobilka;T Frielle;H G Dohlman;M A Bolanowski

  • Role of extracellular disulfide-bonded cysteines in the ligand binding function of the beta 2-adrenergic receptor.

    Henrik G. Dohlman;Marc G. Caron;Antonio DeBlasi;Thomas Frielle

  • Activation of the Phosphatidylinositol 3-Kinase Vps34 by a G Protein α Subunit at the Endosome

    Janna E. Slessareva;Sheri M. Routt;Brenda Temple;Vytas A. Bankaitis

  • Inhibition of G-protein signaling by dominant gain-of-function mutations in Sst2p, a pheromone desensitization factor in Saccharomyces cerevisiae.

    Henrik G. Dohlman;Donald Apaniesk;Yang Chen;Jianping Song

  • The multiple membrane spanning topography of the beta 2-adrenergic receptor. Localization of the sites of binding, glycosylation, and regulatory phosphorylation by limited proteolysis.

    H G Dohlman;M Bouvier;J L Benovic;M G Caron

  • DEP-Domain-Mediated Regulation of GPCR Signaling Responses

    Daniel R. Ballon;Paul L. Flanary;Douglas P. Gladue;James B. Konopka

  • A point mutation in Gα(o) and Gα(i1) blocks interaction with regulator of G protein signaling proteins

    Keng Li Lan;Noune A. Sarvazyan;Ronald Taussig;Robert G. Mackenzie

  • G proteins and pheromone signaling.

    Henrik G. Dohlman

  • Identification and sequence of a binding site peptide of the .beta.2-adrenergic receptor

    Henrik G. Dohlman;Marc G. Caron;Catherine D. Strader;Nourdine Amlaiky

  • The crystal structure of a self-activating G protein alpha subunit reveals its distinct mechanism of signal initiation

    Janice C. Jones;Jeffrey W. Duffy;Mischa Machius;Brenda R. S. Temple

Frequent Co-Authors

Robert J. Lefkowitz
Robert J. Lefkowitz Duke University
Marc G. Caron
Marc G. Caron Duke University
Sharon L. Campbell
Sharon L. Campbell University of North Carolina at Chapel Hill
Jeremy Thorner
Jeremy Thorner University of California, Berkeley
Brian K. Kobilka
Brian K. Kobilka Stanford University
Atsuo T. Sasaki
Atsuo T. Sasaki University of Cincinnati
T. Kendall Harden
T. Kendall Harden University of North Carolina at Chapel Hill
Michel Bouvier
Michel Bouvier University of Montreal
Jeffrey L. Benovic
Jeffrey L. Benovic Thomas Jefferson University
Catherine D. Strader
Catherine D. Strader MSD (United States)

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