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D-Index & Metrics

Biology and Biochemistry

D-Index
61
Citations
12606
World Ranking
11403
National Ranking
4930

Overview

Sharon L. Campbell is affiliated with the University of North Carolina at Chapel Hill in the United States. Their research primarily focuses on the fields of Biochemistry, Genetics and Molecular Biology, with a particular emphasis on Molecular Biology, Cell Biology, Infectious Diseases, Physiology, and Materials Chemistry.

The scientist's work covers various topics including Protein Kinase Regulation and GTPase Signaling, Cellular Mechanics and Interactions, Melanoma and MAPK Pathways, Cellular Transport and Secretion, Protein Structure and Dynamics, Enzyme Structure and Function, and Receptor Mechanisms and Signaling.

Frequent coauthors collaborating with Campbell include:

  • Channing J. Der
  • Venkat R. Chirasani
  • Henrik Dohlman
  • Guowei Yin
  • Nikolay V. Dokholyan

The majority of Campbell's publications appear in venues such as:

  • UNC Libraries
  • Nature Communications
  • Journal of Biological Chemistry
  • Science Signaling
  • bioRxiv (Cold Spring Harbor Laboratory)

Highlighted recent papers authored or co-authored by Campbell include:

  • Post-translational modification of RAS proteins, 2021, Current Opinion in Structural Biology
  • Hospital admission and emergency care attendance risk for SARS-CoV-2 delta (B.1.617.2) compared with alpha (B.1.1.7) variants of concern: a cohort study, 2021, Cronfa (Swansea University)
  • Changes in symptomatology, reinfection, and transmissibility associated with the SARS-CoV-2 variant B.1.1.7: an ecological study, 2021, The Lancet Public Health
  • COVID-19 due to the B.1.617.2 (Delta) variant compared to B.1.1.7 (Alpha) variant of SARS-CoV-2: a prospective observational cohort study, 2022, Scientific Reports
  • A universal allosteric mechanism for G protein activation, 2021, Molecular Cell

Best Publications

  • Increasing complexity of Ras signaling

    Sharon L Campbell;Sharon L Campbell;Roya Khosravi-Far;Kent L Rossman;Geoffrey J Clark

  • A Molecular Redox Switch on p21ras STRUCTURAL BASIS FOR THE NITRIC OXIDE-p21ras INTERACTION

    Harry M. Lander;David P. Hajjar;Barbara L. Hempstead;Urooj A. Mirza

  • Copper is required for oncogenic BRAF signalling and tumorigenesis

    Donita C. Brady;Matthew S. Crowe;Michelle L. Turski;G. Aaron Hobbs

  • DBL FAMILY PROTEINS

    Ian P Whitehead;Sharon Campbell;Kent L Rossman;Channing J Der

  • Rho family proteins and Ras transformation: the RHOad less traveled gets congested

    Irene M Zohn;Sharon L Campbell;Roya Khosravi-Far;Kent L Rossman

  • Recognition and processing of cisplatin- and oxaliplatin-DNA adducts

    Stephen G. Chaney;Sharon L. Campbell;Ekaterina Bassett;Yibing Wu

  • Vav2 is an activator of Cdc42, Rac1, and RhoA.

    Karon Abe;Kent L. Rossman;Betty Liu;Kimberly D. Ritola

  • Molecular mechanism of vinculin activation and nanoscale spatial organization in focal adhesions.

    Lindsay B. Case;Michelle A. Baird;Gleb Shtengel;Sharon L. Campbell

  • A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange.

    Kent L. Rossman;David K. Worthylake;Jason T. Snyder;David P. Siderovski

  • Vinculin–actin interaction couples actin retrograde flow to focal adhesions, but is dispensable for focal adhesion growth

    Ingo Thievessen;Peter M. Thompson;Sylvain Berlemont;Karen M. Plevock

  • Increasing Complexity of Ras Signal Transduction: Involvement of Rho Family Proteins

    Roya Khosravi-Far;Sharon Campbell;Kent L. Rossman;Channing J. Der

  • The solution structure of the Raf-1 cysteine-rich domain: a novel ras and phospholipid binding site.

    Helen R. Mott;John W. Carpenter;Sheng Zhong;Sujoy Ghosh

  • Direct Activation of RhoA by Reactive Oxygen Species Requires a Redox-Sensitive Motif

    Amir Aghajanian;Erika S. Wittchen;Sharon L Campbell;Keith W T Burridge

  • Mutation-Specific RAS Oncogenicity Explains NRAS Codon 61 Selection in Melanoma

    Christin E. Burd;Wenjin Liu;Minh V. Huynh;Meriam A. Waqas

  • Ras interaction with two distinct binding domains in Raf-1 may be required for Ras transformation

    Jonelle K. Drugan;Roya Khosravi-Far;Michael A. White;Channing J. Der

  • 14-3-3 ζ Negatively Regulates Raf-1 Activity by Interactions with the Raf-1 Cysteine-rich Domain

    Geoffrey J. Clark;Jonelle K. Drugan;Kent L. Rossman;John W. Carpenter

  • Atypical KRASG12R Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer.

    G. Aaron Hobbs;Nicole M. Baker;Anne M. Miermont;Ryan D. Thurman

  • Mechanism of redox-mediated guanine nucleotide exchange on redox-active Rho GTPases.

    Jongyun Heo;Sharon L. Campbell

  • ROCK1 and ROCK2 are required for non-small cell lung cancer anchorage-independent growth and invasion.

    Dominico Vigil;Tai Young Kim;Ana Plachco;Andrew J. Garton

  • Abstract IA09: Copper is required for oncogenic BRAF signaling and tumorigenesis

    Donita Brady;Matt Crowe;Michelle Turski;Aaron Hobbs

Frequent Co-Authors

Channing J. Der
Channing J. Der University of North Carolina at Chapel Hill
Nikolay V. Dokholyan
Nikolay V. Dokholyan Pennsylvania State University
Michael D. Schaller
Michael D. Schaller West Virginia University
Carol A. Otey
Carol A. Otey University of North Carolina at Chapel Hill
Atsuo T. Sasaki
Atsuo T. Sasaki University of Cincinnati
Keith Burridge
Keith Burridge University of North Carolina at Chapel Hill
Henrik G. Dohlman
Henrik G. Dohlman University of North Carolina at Chapel Hill
Christopher M. Counter
Christopher M. Counter Duke University
Stefan Knapp
Stefan Knapp Goethe University Frankfurt
Roya Khosravi-Far
Roya Khosravi-Far Beth Israel Deaconess Medical Center

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