What is she best known for?
The fields of study she is best known for:
Her main research concerns Cell biology, Biochemistry, Genetics, Effector and Kinase.
Her biological study spans a wide range of topics, including Transcription factor and Binding site.
Sharon L. Campbell combines subjects such as SH3 domain, Anti-apoptotic Ras signalling cascade and Signal transduction with her study of Effector.
The Anti-apoptotic Ras signalling cascade study combines topics in areas such as Cell surface receptor and Tyrosine kinase.
Her Kinase study frequently intersects with other fields, such as V600E.
The concepts of her GTPase study are interwoven with issues in Pleckstrin homology domain and GTPase-activating protein.
Her most cited work include:
- Increasing complexity of Ras signaling (971 citations)
- Increasing complexity of Ras signaling (971 citations)
- A Molecular Redox Switch on p21ras STRUCTURAL BASIS FOR THE NITRIC OXIDE-p21ras INTERACTION (438 citations)
What are the main themes of her work throughout her whole career to date?
The scientist’s investigation covers issues in Cell biology, Biochemistry, GTPase, Guanine nucleotide exchange factor and Signal transduction.
Her study looks at the relationship between Cell biology and fields such as Cytoskeleton, as well as how they intersect with chemical problems.
In her research, DNA is intimately related to Stereochemistry, which falls under the overarching field of Biochemistry.
While the research belongs to areas of GTPase, Sharon L. Campbell spends her time largely on the problem of RHOA, intersecting her research to questions surrounding CDC42 and VAV2.
Sharon L. Campbell works on Signal transduction which deals in particular with Anti-apoptotic Ras signalling cascade.
Her research in Effector intersects with topics in SH3 domain, Genetics, Function and KRAS.
She most often published in these fields:
- Cell biology (56.69%)
- Biochemistry (30.71%)
- GTPase (27.56%)
What were the highlights of her more recent work (between 2017-2021)?
- Cell biology (56.69%)
- GTPase (27.56%)
- Actin (14.17%)
In recent papers she was focusing on the following fields of study:
Her primary areas of investigation include Cell biology, GTPase, Actin, Vinculin and Effector.
Sharon L. Campbell does research in Cell biology, focusing on Guanine nucleotide exchange factor specifically.
The various areas that Sharon L. Campbell examines in her GTPase study include Ras superfamily and Phosphatidylinositol, Kinase.
In her study, Guanosine triphosphate and GTP' is strongly linked to Membrane ruffling, which falls under the umbrella field of Kinase.
Her Actin research integrates issues from METAVINCULIN and Cytoskeleton.
Her Effector study integrates concerns from other disciplines, such as Cancer research, Guanine, Function, KRAS and Monoubiquitination.
Between 2017 and 2021, her most popular works were:
- Atypical KRASG12R Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer. (33 citations)
- Dominant activating RAC2 mutation with lymphopenia, immunodeficiency and cytoskeletal defects (21 citations)
- Vinculin and metavinculin exhibit distinct effects on focal adhesion properties, cell migration, and mechanotransduction. (7 citations)
In her most recent research, the most cited papers focused on:
Sharon L. Campbell mostly deals with Cell biology, GTPase, Autophagy, Transport protein and Immunogenicity.
Her work on Small G Protein as part of general Cell biology study is frequently connected to OTUB1, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them.
When carried out as part of a general GTPase research project, her work on Guanine nucleotide exchange factor is frequently linked to work in Cellular localization, therefore connecting diverse disciplines of study.
Her Autophagy research includes elements of Cancer research, Pancreatic cancer, Carcinogenesis, Mutation and P110α.
Her Cancer research research is multidisciplinary, incorporating perspectives in KRAS, PI3K/AKT/mTOR pathway and Effector.
Her Transport protein study combines topics in areas such as Epitope, Humoral immunity, Protein engineering and Protein structure.
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