World's Best Scientists 2026 revealed!
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Genetics
UK
2024

D-Index & Metrics

Microbiology

D-Index
100
Citations
40168
World Ranking
400
National Ranking
187

Genetics

D-Index
100
Citations
39849
World Ranking
750
National Ranking
373

Research.com Recognitions

  • 2024 - Research.com Genetics in United Kingdom Leader Award
  • 2023 - Research.com Genetics in United Kingdom Leader Award
  • 2011 - ASM Lifetime Achievement Award, American Society for Microbiology
  • 1999 - Fellow of the American Academy of Arts and Sciences
  • 1998 - Member of the National Academy of Sciences
  • 1997 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Susan Gottesman is affiliated with the National Institutes of Health in the United States. Their research predominantly focuses on the fields of Biochemistry, Genetics, and Molecular Biology, with a specific emphasis on Molecular Biology, Genetics, and Ecology as subfields.

The scientist's work covers several main topics including:

  • Bacterial Genetics and Biotechnology
  • Bacteriophages and microbial interactions
  • RNA and protein synthesis mechanisms
  • Bacterial biofilms and quorum sensing
  • RNA Research and Splicing
  • Legume Nitrogen Fixing Symbiosis
  • Enzyme Structure and Function

Frequent collaborators in their research include Nadim Majdalani, Gisela Storz, Erin Wall, Xing Luo, and Chin-Hsien Tai. Their publications commonly appear in venues such as bioRxiv (Cold Spring Harbor Laboratory), PLoS Genetics, Annual Review of Microbiology, mBio, and the Proceedings of the National Academy of Sciences.

Selected recent papers authored by or associated with Susan Gottesman include:

  • Trans-Acting Small RNAs and Their Effects on Gene Expression in Escherichia coli and Salmonella enterica, 2020, EcoSal Plus
  • Phage Resistance in Multidrug-Resistant Klebsiella pneumoniae ST258 Evolves via Diverse Mutations That Culminate in Impaired Adsorption, 2020, mBio
  • RpoS and the bacterial general stress response, 2024, Microbiology and Molecular Biology Reviews
  • IgaA negatively regulates the Rcs Phosphorelay via contact with the RcsD Phosphotransfer Protein, 2020, PLoS Genetics
  • A fluorescence-based genetic screen reveals diverse mechanisms silencing small RNA signaling in E. coli, 2021, Proceedings of the National Academy of Sciences

Susan Gottesman has been recognized through several awards, including the ASM Lifetime Achievement Award from the American Society for Microbiology in 2011. They were also elected Fellow of the American Academy of Arts and Sciences in 1999 and Member of the National Academy of Sciences in 1998. Additionally, they are a Fellow of the American Association for the Advancement of Science (AAAS), honored in 1997.

Best Publications

  • Posttranslational quality control: folding, refolding, and degrading proteins.

    Sue Wickner;Michael R. Maurizi;Susan Gottesman

  • A small RNA regulates the expression of genes involved in iron metabolism in Escherichia coli.

    Eric Massé;Susan Gottesman

  • The RpoS-mediated general stress response in Escherichia coli.

    Aurelia Battesti;Nadim Majdalani;Susan Gottesman

  • The ClpXP and ClpAP proteases degrade proteins with carboxy-terminal peptide tails added by the SsrA-tagging system

    Susan Gottesman;Eric Roche;YanNing Zhou;Robert T. Sauer

  • Proteases and their targets in Escherichia coli.

    Susan Gottesman

  • Identification of novel small RNAs using comparative genomics and microarrays

    Karen M. Wassarman;Francis Repoila;Carsten Rosenow;Gisela Storz

  • Coupled degradation of a small regulatory RNA and its mRNA targets in Escherichia coli

    Eric Massé;Freddy E. Escorcia;Susan Gottesman

  • Bacterial Small RNA Regulators: Versatile Roles and Rapidly Evolving Variations

    Susan Gottesman;Gisela Storz

  • The Small RNA Regulators of Escherichia coli: Roles and Mechanisms*

    Susan Gottesman

  • THE RCS PHOSPHORELAY: A Complex Signal Transduction System*

    Nadim Majdalani;Susan Gottesman

  • DsrA RNA regulates translation of RpoS message by an anti-antisense mechanism, independent of its action as an antisilencer of transcription

    Nadim Majdalani;Christofer Cunning;Darren Sledjeski;Tom Elliott

  • Micros for microbes: non-coding regulatory RNAs in bacteria.

    Susan Gottesman

  • Protein quality control: triage by chaperones and proteases.

    S Gottesman;S Wickner;M R Maurizi

  • Effect of RyhB Small RNA on Global Iron Use in Escherichia coli

    Eric Massé;Eric Massé;Carin K. Vanderpool;Susan Gottesman

  • Global analysis of small RNA and mRNA targets of Hfq.

    Aixia Zhang;Karen M. Wassarman;Carsten Rosenow;Brian C. Tjaden

  • Proteolysis in bacterial regulatory circuits.

    Susan Gottesman

  • Identification of tandem duplicate regulatory small RNAs in Pseudomonas aeruginosa involved in iron homeostasis

    Paula J. Wilderman;Nathaniel A. Sowa;David J. FitzGerald;Peter C. FitzGerald

  • Regulation and mode of action of the second small RNA activator of RpoS translation, RprA.

    Nadim Majdalani;David Hernandez;Susan Gottesman

  • A molecular chaperone, ClpA, functions like DnaK and DnaJ

    Sue Wickner;Susan Gottesman;Dorota Skowyra;Joel Hoskins

  • Bacterial Regulation: Global Regulatory Networks

    Susan Gottesman

Frequent Co-Authors

Michael R. Maurizi
Michael R. Maurizi National Institutes of Health
Gisela Storz
Gisela Storz National Institutes of Health
Sue Wickner
Sue Wickner MRC Laboratory of Molecular Biology
Laurence Van Melderen
Laurence Van Melderen Université Libre de Bruxelles
Max E. Gottesman
Max E. Gottesman Columbia University Medical Center
Sarah A. Woodson
Sarah A. Woodson Johns Hopkins University
Stephen H. Leppla
Stephen H. Leppla National Institutes of Health
Jörg Vogel
Jörg Vogel University of Würzburg
David J. FitzGerald
David J. FitzGerald MRC Laboratory of Molecular Biology
Jun Chen
Jun Chen Nankai University

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