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Best Female Scientists
2025
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Genetics and Molecular Biology
Germany
2024

D-Index & Metrics

Best Female Scientists

D-Index
112
Citations
44371
World Ranking
820
National Ranking
33

Molecular Biology

D-Index
114
Citations
45769
World Ranking
323
National Ranking
28

Research.com Recognitions

  • 2025 - Research.com Best Female Scientists Award
  • 2024 - Research.com Genetics and Molecular Biology in Germany Leader Award
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Elisa Izaurralde was a researcher affiliated with the Max Planck Institute for Developmental Biology in Germany. Their work was predominantly in the field of Biochemistry, Genetics and Molecular Biology, with focused expertise in Molecular Biology, Immunology, and Genetics.

Their research explored various aspects of RNA biology, including RNA research and splicing, RNA modifications and cancer, and mechanisms of RNA and protein synthesis. Other notable themes in their work involved CRISPR and genetic engineering, genetic and clinical aspects of sex determination and chromosomal abnormalities, interferon and immune responses, and cancer-related gene regulation.

Frequent collaborators in their research included Ramona Weber, Cátia Igreja, Min-Yi Chung, Ulrike Zinnall, and Markus Landthaler.

Elisa Izaurralde published in a range of scientific venues, including Cell Reports, Genes & Development, Nucleic Acids Research, The EMBO Journal, and Molecular Biology and Evolution.

Noteworthy publications by Elisa Izaurralde included:

  • 4EHP and GIGYF1/2 Mediate Translation-Coupled Messenger RNA Decay (2020, Cell Reports)
  • 4E-T-bound mRNAs are stored in a silenced and deadenylated form (2020, Genes & Development)
  • Crystal structure and functional properties of the human CCR4-CAF1 deadenylase complex (2021, Nucleic Acids Research)
  • Rapid Gene Evolution in an Ancient Post-transcriptional and Translational Regulatory System Compensates for Meiotic X Chromosomal Inactivation (2021, Molecular Biology and Evolution)
  • Herpes simplex virus ICP27 protein provides viral mRNAs with access to the cellular mRNA export pathway (2023, The EMBO Journal)

Elisa Izaurralde was recognized as a member of the European Molecular Biology Organization (EMBO).

Best Publications

  • Gene silencing by microRNAs: contributions of translational repression and mRNA decay.

    Eric Huntzinger;Elisa Izaurralde

  • Towards a molecular understanding of microRNA-mediated gene silencing

    Stefanie Jonas;Elisa Izaurralde

  • Getting to the Root of miRNA-Mediated Gene Silencing

    Ana Eulalio;Eric Huntzinger;Elisa Izaurralde

  • mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes

    Isabelle Behm-Ansmant;Jan Rehwinkel;Tobias Doerks;Alexander Stark

  • The spliceosome deposits multiple proteins 20–24 nucleotides upstream of mRNA exon–exon junctions

    Hervé Le Hir;Elisa Izaurralde;Lynne E. Maquat;Melissa J. Moore

  • P bodies: at the crossroads of post-transcriptional pathways

    Ana Eulalio;Isabelle Behm-Ansmant;Elisa Izaurralde

  • The exon–exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay

    Hervé Le Hir;David Gatfield;Elisa Izaurralde;Melissa J. Moore

  • P-Body Formation Is a Consequence, Not the Cause, of RNA-Mediated Gene Silencing

    Ana Eulalio;Isabelle Behm-Ansmant;Daniel Schweizer;Elisa Izaurralde

  • The asymmetric distribution of the constituents of the Ran system is essential for transport into and out of the nucleus

    Elisa Izaurralde;Ulrike Kutay;Cayetano von Kobbe;Iain W. Mattaj

  • TAP, the Human Homolog of Mex67p, Mediates CTE-Dependent RNA Export from the Nucleus

    Patric Grüter;Carlos Tabernero;Cayetano von Kobbe;Christel Schmitt

  • A nuclear cap binding protein complex involved in pre-mRNA splicing

    Elisa Izaurralde;Joe Lewis;Caroline McGuigan;Marzena Jankowska

  • A crucial role for GW182 and the DCP1:DCP2 decapping complex in miRNA-mediated gene silencing

    Jan Rehwinkel;Isabelle Behm-Ansmant;David Gatfield;Elisa Izaurralde

  • Structure and nucleic-acid binding of the Drosophila Argonaute 2 PAZ domain

    Andreas Lingel;Bernd Simon;Elisa Izaurralde;Michael Sattler

  • Deadenylation is a widespread effect of miRNA regulation

    Ana Eulalio;Eric Huntzinger;Tadashi Nishihara;Jan Rehwinkel

  • Nonsense-mediated mRNA decay: molecular insights and mechanistic variations across species

    Elena Conti;Elisa Izaurralde

  • A Novel Class of RanGTP Binding Proteins

    D. Görlich;M. Dabrowski;F. R. Bischoff;U. Kutay

  • GW182 interaction with Argonaute is essential for miRNA-mediated translational repression and mRNA decay

    Ana Eulalio;Eric Huntzinger;Elisa Izaurralde

  • Dominant-negative mutants of importin-beta block multiple pathways of import and export through the nuclear pore complex.

    U. Kutay;E. Izaurralde;F. R. Bischoff;I. W. Mattaj

  • Decay of mRNAs targeted by RISC requires XRN1, the Ski complex, and the exosome

    Tamas I. Orban;Elisa Izaurralde

  • Identification of a tRNA-specific Nuclear Export Receptor

    U. Kutay;G. Lipowsky;E. Izaurralde;F. R. Bischoff

Frequent Co-Authors

Iain W. Mattaj
Iain W. Mattaj Human Technopole
Elena Conti
Elena Conti Max Planck Society
Peer Bork
Peer Bork European Molecular Biology Laboratory
Dirk Görlich
Dirk Görlich Max Planck Society
Matthias Wilm
Matthias Wilm University College Dublin
Ulrike Kutay
Ulrike Kutay ETH Zurich
Michael Sattler
Michael Sattler Technical University of Munich
Angela Bachi
Angela Bachi FIRC Institute of Molecular Oncology
Maria Carmo-Fonseca
Maria Carmo-Fonseca University of Lisbon
Ulrich K. Laemmli
Ulrich K. Laemmli University of Geneva

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