World's Best Scientists 2026 revealed!
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Best Female Scientists
2025

D-Index & Metrics

Best Female Scientists

D-Index
128
Citations
48763
World Ranking
386
National Ranking
234

Biology and Biochemistry

D-Index
131
Citations
50768
World Ranking
394
National Ranking
257

Research.com Recognitions

  • 2025 - Research.com Best Female Scientists Award
  • 2017 - Fellow of the American Academy of Arts and Sciences

Overview

Pamela A. Silver is affiliated with Harvard University in the United States. Their research work spans multiple disciplines within biochemistry, genetics, and molecular biology, with substantial contributions also in the field of medicine. Their studies primarily focus on molecular biology, ecology, infectious diseases, genetics, and related subfields involving ecology, evolution, behavior, and systematics.

The scientist's research topics cover several specialized areas, including:

  • CRISPR and Genetic Engineering
  • Bacteriophages and microbial interactions
  • Tardigrade Biology and Ecology
  • Microbial Community Ecology and Physiology
  • Virus-based gene therapy research
  • Gene Regulatory Network Analysis
  • RNA and protein synthesis mechanisms

Frequent publication venues for Pamela A. Silver include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • ACS Synthetic Biology
  • Nature Methods
  • Nature Communications
  • mSystems

The scientist has collaborated regularly with several coauthors, notably:

  • Jeffrey C. Way
  • Michael Springer
  • Timothy J. Mitchison
  • Samuel Lim
  • Rui Tong Quek

Some of Pamela A. Silver's recent significant publications include:

  • Genetic tool development in marine protists: emerging model organisms for experimental cell biology, 2020, Nature Methods
  • Theranostic cells: emerging clinical applications of synthetic biology, 2021, Nature Reviews Genetics
  • In situ reprogramming of gut bacteria by oral delivery, 2020, Nature Communications
  • The case for biotech on Mars, 2020, Nature Biotechnology
  • Valorization of CO2 through lithoautotrophic production of sustainable chemicals in Cupriavidus necator, 2020, Metabolic Engineering

Pamela A. Silver was recognized as a Fellow of the American Academy of Arts and Sciences in 2017.

Best Publications

  • Genome-wide analysis of estrogen receptor binding sites

    Jason S Carroll;Clifford A Meyer;Jun Song;Wei Li

  • Chromosome-Wide Mapping of Estrogen Receptor Binding Reveals Long-Range Regulation Requiring the Forkhead Protein FoxA1

    Jason S. Carroll;X. Shirley Liu;Alexander S. Brodsky;Wei Li

  • Water splitting–biosynthetic system with CO2 reduction efficiencies exceeding photosynthesis

    Chong Liu;Chong Liu;Brendan Cruz Colon;Marika Ziesack;Pamela A. Silver

  • MyoD is required for myogenic stem cell function in adult skeletal muscle.

    L A Megeney;B Kablar;K Garrett;J E Anderson

  • Toehold Switches: De-Novo-Designed Regulators of Gene Expression

    Alexander A. Green;Pamela A. Silver;James J. Collins;Peng Yin;Peng Yin

  • How proteins enter the nucleus.

    Pamela A. Silver

  • Organization of Intracellular Reactions with Rationally Designed RNA Assemblies

    Camille J. Delebecque;Ariel B. Lindner;Ariel B. Lindner;Pamela A. Silver;Pamela A. Silver;Faisal A. Aldaye;Faisal A. Aldaye

  • Genome-wide localization of the nuclear transport machinery couples transcriptional status and nuclear organization.

    Jason M Casolari;Christopher R Brown;Suzanne Komili;Jason West

  • Engineering cyanobacteria to generate high-value products

    Daniel C. Ducat;Jeffrey C. Way;Pamela A. Silver;Pamela A. Silver

  • State of the arg: protein methylation at arginine comes of age.

    Anne E. McBride;Pamela A. Silver

  • Nuclear transport and cancer: from mechanism to intervention.

    Tweeny R. Kau;Jeffrey C. Way;Pamela A. Silver

  • Regulated nucleo/cytoplasmic exchange of HOG1 MAPK requires the importin beta homologs NMD5 and XPO1.

    Paul Ferrigno;Francesc Posas;Deanna Koepp;Haruo Saito

  • HIV-1 Vpr interacts with the nuclear transport pathway to promote macrophage infection

    Marie A. Vodicka;Deanna M. Koepp;Pamela A. Silver;Michael Emerman

  • Elimination of Replication Block Protein Fob1 Extends the Life Span of Yeast Mother Cells

    Pierre Antoine Defossez;Reeta Prusty;Matt Kaeberlein;Su Ju Lin

  • A chemical genetic screen identifies inhibitors of regulated nuclear export of a Forkhead transcription factor in PTEN-deficient tumor cells.

    Tweeny R Kau;Frank Schroeder;Shivapriya Ramaswamy;Cheryl L Wojciechowski

  • Natural strategies for the spatial optimization of metabolism in synthetic biology.

    Christina M Agapakis;Patrick M Boyle;Pamela A Silver;Pamela A Silver

  • Dynamic Modulation of the Gut Microbiota and Metabolome by Bacteriophages in a Mouse Model.

    Bryan B. Hsu;Bryan B. Hsu;Travis E. Gibson;Vladimir Yeliseyev;Qing Liu

  • Efficient solar-to-fuels production from a hybrid microbial–water-splitting catalyst system

    Joseph P. Torella;Christopher J. Gagliardi;Janice S. Chen;D. Kwabena Bediako

  • Emergent cooperation in microbial metabolism.

    Edwin H Wintermute;Pamela A Silver

  • A protein that shuttles between the nucleus and the cytoplasm is an important mediator of RNA export.

    M S Lee;M Henry;P A Silver

Frequent Co-Authors

Daniel G. Nocera
Daniel G. Nocera Harvard University
Chong Liu
Chong Liu University of California, Los Angeles
Anita H. Corbett
Anita H. Corbett Emory University
Alan Engelman
Alan Engelman Harvard University
Alexander A. Green
Alexander A. Green Boston University
Clifford A. Meyer
Clifford A. Meyer Harvard University
Iñaki Ruiz-Trillo
Iñaki Ruiz-Trillo Pompeu Fabra University
George M. Church
George M. Church Harvard University
Friedrich C. Simmel
Friedrich C. Simmel Technical University of Munich

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