World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
79
Citations
33133
World Ranking
1025
National Ranking
81

Research.com Recognitions

  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Jason S. Carroll is affiliated with the University of Cambridge in the United Kingdom. Their research spans multiple fields with a primary focus on Biochemistry, Genetics and Molecular Biology, encompassing 154 publications. Medicine is another major domain contributing 100 publications. Within these broad areas, specific subfields include Molecular Biology, Oncology, Genetics, Pulmonary and Respiratory Medicine, and Cancer Research.

The scientist's work covers several main research topics, including:

  • Estrogen and related hormone effects
  • Epigenetics and DNA Methylation
  • Genomics and Chromatin Dynamics
  • Cancer Cells and Metastasis
  • HER2/EGFR in Cancer Research
  • Advanced Breast Cancer Therapies
  • Chemical Synthesis and Analysis

Jason S. Carroll has contributed to various recent papers, addressing multiple aspects of cancer biology and molecular mechanisms. Some notable publications include:

  • Site-selective modification strategies in antibody-drug conjugates, 2020, Chemical Society Reviews
  • IL6/STAT3 Signaling Hijacks Estrogen Receptor α Enhancers to Drive Breast Cancer Metastasis, 2020, Cancer Cell
  • The androgen receptor is a tumor suppressor in estrogen receptor-positive breast cancer, 2021, Nature Medicine
  • Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer, 2020, Molecular Cell
  • Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes, 2020, Nature Genetics

Collaborations appear frequently in their research, with key co-authors including Igor Chernukhin, David R. Spring, Stephen J. Walsh, Evangelia K. Papachristou, and Danya Cheeseman. These partnerships have resulted in multiple joint publications.

The scientist's work has been published predominantly in the following venues:

  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • Cancer Research
  • Chemical Communications
  • Nature Genetics
  • bioRxiv (Cold Spring Harbor Laboratory)

Jason S. Carroll is recognized by professional organizations, including membership in the European Molecular Biology Organization (EMBO).

Best Publications

  • Pioneer transcription factors: establishing competence for gene expression

    Kenneth S. Zaret;Jason S. Carroll

  • Genome-wide analysis of estrogen receptor binding sites

    Jason S Carroll;Clifford A Meyer;Jun Song;Wei Li

  • Chromosome-Wide Mapping of Estrogen Receptor Binding Reveals Long-Range Regulation Requiring the Forkhead Protein FoxA1

    Jason S. Carroll;X. Shirley Liu;Alexander S. Brodsky;Wei Li

  • Association analysis identifies 65 new breast cancer risk loci

    Kyriaki Michailidou;Kyriaki Michailidou;Sara Lindström;Sara Lindström;Joe Dennis;Jonathan Beesley

  • FoxA1 Translates Epigenetic Signatures into Enhancer-Driven Lineage-Specific Transcription

    Mathieu Lupien;Jérôme Eeckhoute;Clifford A. Meyer;Qianben Wang

  • Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer

    Qianben Wang;Wei Li;Yong Zhang;Xin Yuan

  • A Hierarchical Network of Transcription Factors Governs Androgen Receptor-Dependent Prostate Cancer Growth

    Qianben Wang;Wei Li;X. Shirley Liu;Jason S. Carroll

  • Progesterone receptor modulates ERα action in breast cancer

    Hisham Mohammed;I. Alasdair Russell;Rory Stark;Oscar M. Rueda

  • Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer

    Shaokun Shu;Charles Y. Lin;Housheng Hansen He;Robert M. Witwicki

  • Spatial and Temporal Recruitment of Androgen Receptor and Its Coactivators Involves Chromosomal Looping and Polymerase Tracking

    Qianben Wang;Qianben Wang;Jason S. Carroll;Jason S. Carroll;Myles Brown;Myles Brown

  • Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer.

    Suzanne A. Eccles;Eric O. Aboagye;Simak Ali;Annie S. Anderson

  • Model-based analysis of tiling-arrays for ChIP-chip

    W. Evan Johnson;Wei Li;Clifford A. Meyer;Raphael Gottardo

  • p63 regulates an adhesion programme and cell survival in epithelial cells.

    Danielle K. Carroll;Jason S. Carroll;Chee-Onn Leong;Fang Cheng;Fang Cheng

  • Integrative analysis of HIF binding and transactivation reveals its role in maintaining histone methylation homeostasis

    Xiaobo Xia;Madeleine E. Lemieux;Wei Li;Jason S. Carroll

  • A CTCF-independent role for cohesin in tissue-specific transcription

    Dominic Schmidt;Petra C. Schwalie;Caryn S. Ross-Innes;Antoni Hurtado

  • Estrogen and antiestrogen regulation of cell cycle progression in breast cancer cells.

    S F Doisneau-Sixou;C M Sergio;J S Carroll;R Hui

  • Estrogen protects bone by inducing Fas ligand in osteoblasts to regulate osteoclast survival.

    Susan A Krum;Gustavo A Miranda-Carboni;Peter V Hauschka;Jason S Carroll

  • Regulation of ERBB2 by oestrogen receptor–PAX2 determines response to tamoxifen

    Antoni Hurtado;Kelly A. Holmes;Timothy R. Geistlinger;Iain Robert Hutcheson

  • Positive Cross-Regulatory Loop Ties GATA-3 to Estrogen Receptor α Expression in Breast Cancer

    Jérôme Eeckhoute;Erika Krasnickas Keeton;Mathieu Lupien;Susan A. Krum

  • Estradiol-regulated microRNAs control estradiol response in breast cancer cells

    Poornima Bhat-Nakshatri;Guohua Wang;Nikail R. Collins;Michael J. Thomson

Frequent Co-Authors

Myles Brown
Myles Brown Harvard University
Wayne D. Tilley
Wayne D. Tilley University of Adelaide
Alexander Swarbrick
Alexander Swarbrick Garvan Institute of Medical Research
Carlos Caldas
Carlos Caldas University of Cambridge
X. Shirley Liu
X. Shirley Liu Harvard University
Ian G. Mills
Ian G. Mills University of Oxford
Wei Li
Wei Li Harvard University
Simak Ali
Simak Ali Imperial College London
David E. Neal
David E. Neal University of Cambridge
Mathieu Lupien
Mathieu Lupien Princess Margaret Cancer Centre

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