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Simak Ali

D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
15938
World Ranking
10670
National Ranking
816

Simak Ali publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Simak Ali sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 189 publications — 45th percentile

45% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Simak Ali D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Simak Ali sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 62 D-Index — 46th percentile

46% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Simak Ali is affiliated with Imperial College London in the United Kingdom. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a substantial focus on Molecular Biology and Oncology.

Their work encompasses several subfields including Pulmonary and Respiratory Medicine, Cancer Research, and Genetics. Key topics addressed in their research include Advanced Breast Cancer Therapies, Cancer Genomics and Diagnostics, Cancer-related Molecular Pathways, Ubiquitin and Proteasome Pathways, Cancer Cells and Metastasis, Genomics and Chromatin Dynamics, and Estrogen and Related Hormone Effects.

Among Simak Ali's recent papers are:

  • "CDK7 inhibitors as anticancer drugs," 2020, Cancer and Metastasis Reviews
  • "Hotspot ESR1 Mutations Are Multimodal and Contextual Modulators of Breast Cancer Metastasis," 2022, Cancer Research
  • "ESR1 mutant breast cancers show elevated basal cytokeratins and immune activation," 2022, Nature Communications
  • "Epithelial-mesenchymal plasticity determines estrogen receptor positive breast cancer dormancy and epithelial reconversion drives recurrence," 2022, Nature Communications
  • "Dose escalation and expansion cohorts in patients with advanced breast cancer in a Phase I study of the CDK7-inhibitor samuraciclib," 2023, Nature Communications

The scientist has collaborated frequently with other researchers, including:

  • R. Charles Coombes
  • Jacqui Shaw
  • Carlo Palmieri
  • Manikandan Periyasamy
  • Rebecca C. Allsopp

Simak Ali's publications have appeared in multiple venues, with notable contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research
  • Nature Communications
  • Oncogene
  • JCO Precision Oncology

Best Publications

  • Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance.

    Robert A. Campbell;Poornima Bhat-Nakshatri;Nikhil M. Patel;Demetra Constantinidou

  • Endocrine-responsive breast cancer and strategies for combating resistance.

    Simak Ali;R. Charles Coombes

  • Modulation of transcriptional activation by ligand-dependent phosphorylation of the human oestrogen receptor A/B region.

    Simak Ali;D. Metzger;J.-M. Bornert;P. Chambon

  • Trichostatin A is a histone deacetylase inhibitor with potent antitumor activity against breast cancer in vivo.

    D M Vigushin;S Ali;P E Pace;N Mirsaidi

  • Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer.

    Suzanne A. Eccles;Eric O. Aboagye;Simak Ali;Annie S. Anderson

  • Personalized Detection of Circulating Tumor DNA Antedates Breast Cancer Metastatic Recurrence

    Raoul Charles Coombes;Karen Page;Raheleh Salari;Robert K. Hastings

  • Human estrogen receptor beta binds DNA in a manner similar to and dimerizes with estrogen receptor alpha.

    P Pace;J Taylor;S Suntharalingam;R C Coombes

  • Estrogen receptor alpha in human breast cancer: occurrence and significance.

    S Ali;R C Coombes

  • Regulation of ERBB2 by oestrogen receptor–PAX2 determines response to tamoxifen

    Antoni Hurtado;Kelly A. Holmes;Timothy R. Geistlinger;Iain Robert Hutcheson

  • Enhanced Estrogen Receptor (ER) α, ERBB2, and MAPK Signal Transduction Pathways Operate during the Adaptation of MCF-7 Cells to Long Term Estrogen Deprivation

    Lesley-Ann Martin;Ian Farmer;Stephen R.D. Johnston;Simak Ali

  • Activation of Estrogen Receptor α by S118 Phosphorylation Involves a Ligand-Dependent Interaction with TFIIH and Participation of CDK7

    Dongsheng Chen;Thilo Riedl;Elinor Washbrook;Paul E. Pace

  • Phosphorylation of Human Estrogen Receptor α by Protein Kinase A Regulates Dimerization

    Dongsheng Chen;Paul E. Pace;R. Charles Coombes;Simak Ali

  • Characterization of the Amino-terminal Transcriptional Activation Function of the Human Estrogen Receptor in Animal and Yeast Cells

    Daniel Metzger;Simak Ali;Jean-Marc Bornert;Pierre Chambon

  • Phosphorylation of human estrogen receptor α at serine 118 by two distinct signal transduction pathways revealed by phosphorylation-specific antisera

    Dongsheng Chen;Elinor Washbrook;Naveed Sarwar;Gaynor J. Bates

  • Preoperative gefitinib versus gefitinib and anastrozole in postmenopausal patients with oestrogen-receptor positive and epidermal-growth-factor-receptor-positive primary breast cancer: a double-blind placebo-controlled phase II randomised trial.

    Andreas Polychronis;H Dudley Sinnett;Dimitri Hadjiminas;Hemant Singhal

  • Mutation Analysis of Cell-Free DNA and Single Circulating Tumor Cells in Metastatic Breast Cancer Patients with High Circulating Tumor Cell Counts

    Jacqueline A. Shaw;David S. Guttery;A. Hills;Daniel Fernandez-Garcia

  • A Common Deletion in the APOBEC3 Genes and Breast Cancer Risk

    Jirong Long;Ryan J. Delahanty;Guoliang Li;Yu-Tang Gao

  • Molecular changes associated with the acquisition of oestrogen hypersensitivity in MCF-7 breast cancer cells on long-term oestrogen deprivation.

    Christina M.W Chan;Lesley-Ann Martin;Stephen R.D Johnston;Simak Ali

  • Phosphorylation at serines 104 and 106 by Erk1/2 MAPK is important for estrogen receptor-α activity

    Ross S Thomas;Naveed Sarwar;Fladia Phoenix;R Charles Coombes

  • Immunohistochemical determination of estrogen receptor-alpha phosphorylation in activation function AF1 in primary and tamoxifen-resistant breast cancer is indicative of a complex role for estrogen receptor-alpha phosphorylation in breast cancer progression [Abstract]

    S. Ali;N. Sarwar;J. Jiang;D. Peston

Frequent Co-Authors

R. Charles Coombes
R. Charles Coombes Imperial College London
Anthony G. M. Barrett
Anthony G. M. Barrett Imperial College London
Matthew J. Fuchter
Matthew J. Fuchter Imperial College London
Jason S. Carroll
Jason S. Carroll University of Cambridge
Emad A. Rakha
Emad A. Rakha University of Nottingham
James P. Snyder
James P. Snyder Emory University
Ian O. Ellis
Ian O. Ellis University of Nottingham
Justin Stebbing
Justin Stebbing Imperial College London
Pierre Chambon
Pierre Chambon Institute of Genetics and Molecular and Cellular Biology
Andrew R. Green
Andrew R. Green University of Nottingham

External Links

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These online programs complement traditional biology or biochemistry studies, and can help you tailor your education for high-demand, rewarding career pathways in science and health.

Best Scientists Citing Simak Ali

Mitch Dowsett

Mitch Dowsett

Breast Cancer Research Foundation

Publications: 76

Jan-Åke Gustafsson

Jan-Åke Gustafsson

University of Houston

Publications: 49

Cécile Rochette-Egly

Cécile Rochette-Egly

Institute of Genetics and Molecular and Cellular Biology

Publications: 47

Pierre Chambon

Pierre Chambon

Institute of Genetics and Molecular and Cellular Biology

Publications: 47

Justin Stebbing

Justin Stebbing

Imperial College London

Publications: 39

Benita S. Katzenellenbogen

Benita S. Katzenellenbogen

University of Illinois at Urbana-Champaign

Publications: 37

Robert Ian Nicholson

Robert Ian Nicholson

Cardiff University

Publications: 37

Julia Margaret Wendy Gee

Julia Margaret Wendy Gee

Cardiff University

Publications: 31

Harikrishna Nakshatri

Harikrishna Nakshatri

Indiana University

Publications: 29

Jason S. Carroll

Jason S. Carroll

University of Cambridge

Publications: 29

R. Charles Coombes

R. Charles Coombes

Imperial College London

Publications: 28

Rachel Schiff

Rachel Schiff

Baylor College of Medicine

Publications: 28

Suzanne A. W. Fuqua

Suzanne A. W. Fuqua

Baylor College of Medicine

Publications: 26

C. Kent Osborne

C. Kent Osborne

Baylor College of Medicine

Publications: 25

Leigh C. Murphy

Leigh C. Murphy

University of Manitoba

Publications: 25

Jean-Marc Egly

Jean-Marc Egly

Institute of Genetics and Molecular and Cellular Biology

Publications: 25

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