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Harikrishna Nakshatri

Harikrishna Nakshatri

D-Index & Metrics

Biology and Biochemistry

D-Index
76
Citations
22077
World Ranking
5017
National Ranking
2408

Overview

Harikrishna Nakshatri is affiliated with Indiana University in the United States. Their research spans multiple fields, notably Biochemistry, Genetics and Molecular Biology, as well as Medicine. Within these broad domains, their work focuses on several subfields, including Molecular Biology, Oncology, Cancer Research, Genetics, and Pulmonary and Respiratory Medicine.

Their scientific contributions address key topics such as:

  • Cancer Cells and Metastasis
  • Cancer Genomics and Diagnostics
  • Single-cell and spatial transcriptomics
  • Cancer, Hypoxia, and Metabolism
  • Muscle Physiology and Disorders
  • Advanced Breast Cancer Therapies
  • Cancer-related Molecular Pathways

Recent publications authored or co-authored by Nakshatri include:

  • "A single-cell atlas of the healthy breast tissues reveals clinically relevant clusters of breast epithelial cells," 2021, Cell Reports Medicine
  • "Nexus between PI3K/AKT and Estrogen Receptor Signaling in Breast Cancer," 2021, Cancers
  • "Skeletal loading regulates breast cancer-associated osteolysis in a loading intensity-dependent fashion," 2020, Bone Research
  • "Deubiquitinase UCHL1 Maintains Protein Homeostasis through the PSMA7-APEH-Proteasome Axis in High-grade Serous Ovarian Carcinoma," 2021, Molecular Cancer Research
  • "Aged Breast Extracellular Matrix Drives Mammary Epithelial Cells to an Invasive and Cancer-Like Phenotype," 2021, Advanced Science

Nakshatri frequently publishes in several established scientific venues. Notable among these are:

  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of IMPRS
  • Bone Research
  • Cancer Research Communications

The scientist has collaborated extensively with multiple colleagues. Frequent co-authors include:

  • Poornima Bhat-Nakshatri
  • George E. Sandusky
  • Yunlong Liu
  • Anna Maria Storniolo
  • Aditi S. Khatpe

Best Publications

  • Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently

    Mark Leid;Mark Leid;Philippe Kastner;Philippe Kastner;Ruth Lyons;Ruth Lyons;Harikrishna Nakshatri;Harikrishna Nakshatri

  • Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance.

    Robert A. Campbell;Poornima Bhat-Nakshatri;Nikhil M. Patel;Demetra Constantinidou

  • CD44 + /CD24 - breast cancer cells exhibit enhanced invasive properties: an early step necessary for metastasis

    Carol Sheridan;Hiromitsu Kishimoto;Robyn K Fuchs;Sanjana Mehrotra

  • Constitutive activation of NF-kappaB during progression of breast cancer to hormone-independent growth.

    Harikrishna Nakshatri;Poornima Bhat-Nakshatri;Daniel A. Martin;Robert J. Goulet

  • NF-κ B Promotes Breast Cancer Cell Migration and Metastasis by Inducing the Expression of the Chemokine Receptor CXCR4

    Gregory Helbig;Kent W. Christopherson;Poornima Bhat-Nakshatri;Suresh Kumar

  • NF-κB represses E-cadherin expression and enhances epithelial to mesenchymal transition of mammary epithelial cells: potential involvement of ZEB-1 and ZEB-2

    H L Chua;P Bhat-Nakshatri;S E Clare;A Morimiya

  • Cutting edge: IL-17F, a novel cytokine selectively expressed in activated T cells and monocytes, regulates angiogenesis and endothelial cell cytokine production.

    Trevor Starnes;Michael J. Robertson;George Sledge;Stephanie Kelich

  • Promoter context- and response element-dependent specificity of the transcriptional activation and modulating functions of retinoic acid receptors

    Sunil Nagpal;Sunil Nagpal;Michael Saunders;Michael Saunders;Philippe Kastner;Philippe Kastner;Béatrice Durand;Béatrice Durand

  • RARs and RXRs: evidence for two autonomous transactivation functions (AF-1 and AF-2) and heterodimerization in vivo.

    S. Nagpal;S. Friant;Harikrishna Nakshatri;P. Chambon

  • Estradiol-regulated microRNAs control estradiol response in breast cancer cells

    Poornima Bhat-Nakshatri;Guohua Wang;Nikail R. Collins;Michael J. Thomson

  • Paclitaxel sensitivity of breast cancer cells with constitutively active NF-κB is enhanced by IκBα super-repressor and parthenolide

    Nikhil M Patel;Shinichi Nozaki;Nicholas H Shortle;Poornima Bhat-Nakshatri

  • PROGgeneV2: enhancements on the existing database

    Chirayu Pankaj Goswami;Harikrishna Nakshatri

  • FOXA1 expression in breast cancer - Correlation with luminal subtype A and survival

    Sunil Badve;Dmitry Turbin;Mangesh A. Thorat;Akira Morimiya

  • A retinoic acid response element is present in the mouse cellular retinol binding protein I (mCRBPI) promoter.

    W.C. Smith;H. Nakshatri;P. Leroy;J. Rees

  • Mouse retinoic acid receptor alpha 2 isoform is transcribed from a promoter that contains a retinoic acid response element

    Pierre Leroy;Harikrishna Nakshatri;Pierre Chambon

  • Cloning of BRAK, a Novel Divergent CXC Chemokine Preferentially Expressed in Normal versus Malignant Cells

    Robert Hromas;Hal E. Broxmeyer;Chang Kim;Harikrishna Nakshatri

  • Prognostic impact of ALDH1 in breast cancer: a story of stem cells and tumor microenvironment.

    Erika Resetkova;Jorge S. Reis-Filho;Rohit K. Jain;Rutika Mehta

  • The sesquiterpene lactone parthenolide in combination with docetaxel reduces metastasis and improves survival in a xenograft model of breast cancer

    Christopher J. Sweeney;Sanjana Mehrotra;Miral R. Sadaria;Suresh Kumar

  • Breast-cancer stem cells—beyond semantics

    Sunil Badve;Harikrishna Nakshatri

  • Nuclear Factor-κB Is Constitutively Activated in Prostate Cancer In vitro and Is Overexpressed in Prostatic Intraepithelial Neoplasia and Adenocarcinoma of the Prostate

    Christopher Sweeney;Lang Li;Rajasubramaniam Shanmugam;Poornima Bhat-Nakshatri

Frequent Co-Authors

Sunil Badve
Sunil Badve Emory University
Christopher Sweeney
Christopher Sweeney Harvard University
Yunlong Liu
Yunlong Liu Indiana University
Peter A. Crooks
Peter A. Crooks University of Arkansas for Medical Sciences
Kathy D. Miller
Kathy D. Miller Indiana University
George W. Sledge
George W. Sledge Stanford University
Kenneth P. Nephew
Kenneth P. Nephew Indiana University
Pierre Chambon
Pierre Chambon Institute of Genetics and Molecular and Cellular Biology
Edward F. Srour
Edward F. Srour Indiana University
Howard J. Edenberg
Howard J. Edenberg Indiana University

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