His primary scientific interests are in Cancer research, Molecular biology, Cancer cell, Response element and Retinoic acid. His study in Cancer research is interdisciplinary in nature, drawing from both Cell culture, Carcinogenesis, Cancer, Estrogen receptor beta and Estrogen. Harikrishna Nakshatri has researched Cancer cell in several fields, including Epithelial–mesenchymal transition, Metastasis, Stromal cell, Cancer stem cell and Myoepithelial cell.
His study on Retinoic acid also encompasses disciplines like
Harikrishna Nakshatri mainly focuses on Cancer research, Breast cancer, Cancer, Internal medicine and Cancer cell. His Cancer research research incorporates elements of Cell, Cancer stem cell, Estrogen receptor, Estrogen receptor alpha and Metastasis. His studies deal with areas such as Tissue microarray, Gene, Bioinformatics and Pathology as well as Breast cancer.
His Cancer research integrates issues from Cell type, Pharmacology and Skeletal muscle. His Internal medicine research is multidisciplinary, incorporating elements of Endocrinology, microRNA and Oncology. His research integrates issues of Molecular biology, Stromal cell, Signal transduction and Cytokine in his study of Cancer cell.
His primary areas of investigation include Cancer research, Breast cancer, Cancer, Cell and Gene. His Cancer research study combines topics in areas such as CD44, Cancer cell, Estrogen receptor, Cell cycle and Cell type. He has included themes like Carcinogenesis, Cancer stem cell and Doxorubicin in his Cancer cell study.
His biological study spans a wide range of topics, including Transcriptome, Metastasis, Tissue microarray and DNA methylation. The concepts of his Cancer study are interwoven with issues in Progenitor cell and Immortalised cell line. His research investigates the connection between Cell and topics such as Immune system that intersect with problems in GATA3.
His primary areas of study are Cancer research, Cancer, Breast cancer, Cell type and Cell culture. His work carried out in the field of Cancer research brings together such families of science as CD44, Mammary tumor, Estrogen receptor alpha, Ovarian cancer and Epigenetics. While the research belongs to areas of CD44, Harikrishna Nakshatri spends his time largely on the problem of Estrogen receptor, intersecting his research to questions surrounding Carcinogenesis, Cancer cell and Gene knockdown.
His research in Cancer intersects with topics in Death effector domain and Effector. The study incorporates disciplines such as Type I collagen, Downregulation and upregulation, IκBα, Biochemistry and Cell biology in addition to Cell culture. As part of one scientific family, Harikrishna Nakshatri deals mainly with the area of Cell biology, narrowing it down to issues related to the Gene isoform, and often Immune system.
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Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently
Mark Leid;Mark Leid;Philippe Kastner;Philippe Kastner;Ruth Lyons;Ruth Lyons;Harikrishna Nakshatri;Harikrishna Nakshatri.
Cell (1992)
Phosphatidylinositol 3-Kinase/AKT-mediated Activation of Estrogen Receptor α A NEW MODEL FOR ANTI-ESTROGEN RESISTANCE
Robert A. Campbell;Poornima Bhat-Nakshatri;Nikhil M. Patel;Demetra Constantinidou.
Journal of Biological Chemistry (2001)
CD44 + /CD24 - breast cancer cells exhibit enhanced invasive properties: an early step necessary for metastasis
Carol Sheridan;Hiromitsu Kishimoto;Robyn K Fuchs;Sanjana Mehrotra.
Breast Cancer Research (2006)
Constitutive activation of NF-kappaB during progression of breast cancer to hormone-independent growth.
Harikrishna Nakshatri;Poornima Bhat-Nakshatri;Daniel A. Martin;Robert J. Goulet.
Molecular and Cellular Biology (1997)
NF-κ B Promotes Breast Cancer Cell Migration and Metastasis by Inducing the Expression of the Chemokine Receptor CXCR4
Gregory Helbig;Kent W. Christopherson;Poornima Bhat-Nakshatri;Suresh Kumar.
Journal of Biological Chemistry (2003)
NF-κB represses E-cadherin expression and enhances epithelial to mesenchymal transition of mammary epithelial cells: Potential involvement of ZEB-1 and ZEB-2
H L Chua;P Bhat-Nakshatri;S E Clare;A Morimiya.
Oncogene (2007)
Cutting edge: IL-17F, a novel cytokine selectively expressed in activated T cells and monocytes, regulates angiogenesis and endothelial cell cytokine production.
Trevor Starnes;Michael J. Robertson;George Sledge;Stephanie Kelich.
Journal of Immunology (2001)
RARs and RXRs: evidence for two autonomous transactivation functions (AF-1 and AF-2) and heterodimerization in vivo.
S. Nagpal;S. Friant;Harikrishna Nakshatri;P. Chambon.
The EMBO Journal (1993)
Promoter context- and response element-dependent specificity of the transcriptional activation and modulating functions of retinoic acid receptors
Sunil Nagpal;Sunil Nagpal;Michael Saunders;Michael Saunders;Philippe Kastner;Philippe Kastner;Béatrice Durand;Béatrice Durand.
Cell (1992)
Estradiol-regulated microRNAs control estradiol response in breast cancer cells
Poornima Bhat-Nakshatri;Guohua Wang;Nikail R. Collins;Michael J. Thomson.
Nucleic Acids Research (2009)
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