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Molecular Biology

D-Index
52
Citations
16450
World Ranking
2409
National Ranking
190

Overview

Jacqui A. Shaw is affiliated with the University of Leicester in the United Kingdom. Their research spans primarily the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a significant focus on cancer-related studies.

The scientist has contributed extensively to subfields including Cancer Research, Molecular Biology, Pulmonary and Respiratory Medicine, Oncology, and Pathology and Forensic Medicine.

Their work covers a variety of topics with notable emphasis on Cancer Genomics and Diagnostics, Lung Cancer Treatments and Mutations, Genetic factors in colorectal cancer, Cancer Cells and Metastasis, Lung Cancer Research Studies, and RNA modifications and cancer.

Recent significant publications by Jacqui A. Shaw include:

  • Lung adenocarcinoma promotion by air pollutants, 2023, Nature
  • Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA, 2023, Nature
  • The evolution of lung cancer and impact of subclonal selection in TRACERx, 2023, Nature
  • The evolution of non-small cell lung cancer metastases in TRACERx, 2023, Nature
  • Cell-free DNA analysis in current cancer clinical trials: a review, 2022, British Journal of Cancer

The frequent co-authors collaborating with Jacqui A. Shaw include Karen Page, Rebecca C. Allsopp, R. Charles Coombes, Selvaraju Veeriah, and Maise Al Bakir, highlighting a network of ongoing research partnerships.

Jacqui A. Shaw's work has been published in prominent venues, with multiple contributions to:

  • Endocrine Abstracts
  • Nature
  • British Journal of Cancer
  • Cancer Research
  • Oncogene

Best Publications

  • Tracking the Evolution of Non–Small-Cell Lung Cancer

    Mariam Jamal-Hanjani;Gareth A. Wilson;Nicholas McGranahan;Nicolai Juul Birkbak

  • Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution

    Christopher Abbosh;Nicolai J. Birkbak;Nicolai J. Birkbak;Gareth A. Wilson;Gareth A. Wilson;Mariam Jamal-Hanjani

  • Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution

    Nicholas McGranahan;Rachel Rosenthal;Crispin T. Hiley;Crispin T. Hiley;Andrew J. Rowan

  • Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies

    Frederick Arce Vargas;Andrew J S Furness;Kevin Litchfield;Kroopa Joshi

  • Methylation associated inactivation of RASSF1A from region 3p21.3 in lung, breast and ovarian tumours.

    Angelo Agathanggelou;Sofia Honorio;Donia P Macartney;Alonso Martinez

  • Personalized Detection of Circulating Tumor DNA Antedates Breast Cancer Metastatic Recurrence

    Raoul Charles Coombes;Karen Page;Raheleh Salari;Robert K. Hastings

  • Comparison of microfluidic digital PCR and conventional quantitative PCR for measuring copy number variation

    Alexandra S. Whale;Jim F. Huggett;Simon Cowen;Valerie Speirs

  • Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors.

    Frederick Arce Vargas;Andrew J.S. Furness;Andrew J.S. Furness;Isabelle Solomon;Kroopa Joshi;Kroopa Joshi

  • Mapping of mutation causing Friedreich's ataxia to human chromosome 9.

    Susan Chamberlain;Jacqui Shaw;Alison Rowland;Julie Wallis

  • Tracking Genomic Cancer Evolution for Precision Medicine: The Lung TRACERx Study

    Mariam Jamal-Hanjani;Alan Hackshaw;Yenting Ngai;Jacqueline Shaw

  • A framework for the development of effective anti-metastatic agents.

    Robin L. Anderson;Robin L. Anderson;Theo Balasas;Juliana Callaghan;R. Charles Coombes

  • Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma

    Lewis Au;Lewis Au;Emine Hatipoglu;Emine Hatipoglu;Marc Robert de Massy;Kevin Litchfield

  • Mutation Analysis of Cell-Free DNA and Single Circulating Tumor Cells in Metastatic Breast Cancer Patients with High Circulating Tumor Cell Counts

    Jacqueline A. Shaw;David S. Guttery;A. Hills;Daniel Fernandez-Garcia

  • Genomic analysis of circulating cell-free DNA infers breast cancer dormancy

    Jacqueline A. Shaw;Karen Page;Kevin Blighe;Natasha Hava

  • Noninvasive Detection of Activating Estrogen Receptor 1 (ESR1) Mutations in Estrogen Receptor–Positive Metastatic Breast Cancer

    David S. Guttery;Karen Page;Allison Hills;Laura Woodley

  • Tumour-associated tenascin-C isoforms promote breast cancer cell invasion and growth by matrix metalloproteinase-dependent and independent mechanisms

    Rachael A Hancox;Michael D Allen;Deborah L Holliday;Dylan R Edwards

  • Oestrogen receptors alpha and beta differ in normal human breast and breast carcinomas.

    Jacqueline A Shaw;Kufre Udokang;Juan-Miguel Mosquera;Hina Chauhan

  • Microsatellite alterations plasma DNA of primary breast cancer patients.

    J A Shaw;B M Smith;T Walsh;Suzanne Johnson

  • Primary breast myoepithelial cells exert an invasion-suppressor effect on breast cancer cells via paracrine down-regulation of MMP expression in fibroblasts and tumour cells

    J.L. Jones;J.A. Shaw;J.H. Pringle;Rosemary A. Walker

  • Isolation and Extraction of Circulating Tumor DNA from Patients with Small Cell Lung Cancer

    Ruth E. Board;Ruth E. Board;Victoria S. Williams;Lucy Knight;Jacqueline Shaw

Frequent Co-Authors

Charles Swanton
Charles Swanton The Francis Crick Institute
Samra Turajlic
Samra Turajlic Royal Marsden NHS Foundation Trust
Nicholas McGranahan
Nicholas McGranahan University College London
Peter Van Loo
Peter Van Loo The Francis Crick Institute
Ian O. Ellis
Ian O. Ellis University of Nottingham
Caroline Dive
Caroline Dive University of Manchester
Fiona H Blackhall
Fiona H Blackhall University of Manchester
Sergio A. Quezada
Sergio A. Quezada University College London
Simak Ali
Simak Ali Imperial College London
Robert Williamson
Robert Williamson University of Melbourne

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