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Jonas Demeulemeester

Jonas Demeulemeester

D-Index & Metrics

Molecular Biology

D-Index
46
Citations
13389
World Ranking
2779
National Ranking
35

Overview

Jonas Demeulemeester is affiliated with KU Leuven in Belgium and has contributed extensively to the fields of Biochemistry, Genetics, and Molecular Biology, with a total of 136 publications. Their work also spans Medicine, with 52 publications. Within these areas, their research engages deeply with subfields including Molecular Biology, Cancer Research, Genetics, Immunology, and Pulmonary and Respiratory Medicine.

The primary research topics Jonas focuses on include Cancer Genomics and Diagnostics, RNA modifications and cancer, Genomics and Phylogenetic Studies, Genomics and Rare Diseases, Single-cell and spatial transcriptomics, Cancer-related molecular mechanisms research, and Epigenetics and DNA Methylation.

Jonas's research has been published frequently in venues such as bioRxiv (Cold Spring Harbor Laboratory), Cancer Research, Nature, Nature Biotechnology, and Nature Communications. These platforms highlight the interdisciplinary nature and scientific reach of their work.

Their recent papers include:

  • The evolutionary history of 2,658 cancers (2020, Nature)
  • Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes (2021, Cell)
  • Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition (2020, Nature Genetics)
  • Pervasive chromosomal instability and karyotype order in tumour evolution (2020, Nature)
  • Antibodies against endogenous retroviruses promote lung cancer immunotherapy (2023, Nature)

Throughout their career, Jonas has collaborated frequently with several researchers, including:

  • Peter Van Loo (53 publications)
  • Maxime Tarabichi (22 publications)
  • Stefan C. Dentro (21 publications)
  • Ignaty Leshchiner (17 publications)
  • Paul C. Boutros (17 publications)

Best Publications

  • Pan-cancer analysis of whole genomes

    Peter J. Campbell;Gad Getz;Jan O. Korbel;Joshua M. Stuart

  • The evolutionary history of 2,658 cancers

    Moritz Gerstung;Moritz Gerstung;Clemency Jolly;Ignaty Leshchiner;Stefan C Dentro;Stefan C Dentro;Stefan C Dentro

  • Patterns of somatic structural variation in human cancer genomes

    Yilong Li;Nicola D Roberts;Jeremiah A Wala;Jeremiah A Wala;Ofer Shapira;Ofer Shapira

  • Neoantigen-directed immune escape in lung cancer evolution

    Rachel Rosenthal;Rachel Rosenthal;Elizabeth Larose Cadieux;Roberto Salgado;Maise Al Bakir

  • Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes

    Stefan C. Dentro;Stefan C. Dentro;Stefan C. Dentro;Ignaty Leshchiner;Kerstin Haase;Maxime Tarabichi;Maxime Tarabichi

  • Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition.

    Bernardo Rodriguez-Martin;Bernardo Rodriguez-Martin;Eva G. Alvarez;Eva G. Alvarez;Adrian Baez-Ortega;Jorge Zamora

  • Pervasive chromosomal instability and karyotype order in tumour evolution.

    Thomas B. K. Watkins;Emilia L. Lim;Emilia L. Lim;Marina Petkovic;Sergi Elizalde

  • Small-Molecule Inhibitors of the LEDGF/p75 Binding Site of Integrase Block HIV Replication and Modulate Integrase Multimerization

    Frauke Christ;Stephen Shaw;Jonas Demeulemeester;Belete Ayele Desimmie

  • The BET family of proteins targets moloney murine leukemia virus integration near transcription start sites

    Jan De Rijck;Christine de Kogel;Jonas Demeulemeester;Sofie Vets

  • LEDGINs inhibit late stage HIV-1 replication by modulating integrase multimerization in the virions

    Belete Ayele Desimmie;Rik Schrijvers;Jonas Demeulemeester;Doortje Borrenberghs

  • LEDGF/p75-Independent HIV-1 Replication Demonstrates a Role for HRP-2 and Remains Sensitive to Inhibition by LEDGINs

    Rik Schrijvers;Jan De Rijck;Jonas Demeulemeester;Noritaka Adachi

  • Recurrent rearrangements of FOS and FOSB define osteoblastoma.

    Matthew W. Fittall;Matthew W. Fittall;Matthew W. Fittall;William Mifsud;William Mifsud;William Mifsud;Nischalan Pillay;Nischalan Pillay;Hongtao Ye

  • LEDGIN-mediated Inhibition of Integrase-LEDGF/p75 Interaction Reduces Reactivation of Residual Latent HIV

    Lenard S. Vranckx;Jonas Demeulemeester;Suha Saleh;Annegret Boll

  • Evolutionary predictability of genetic versus nongenetic resistance to anticancer drugs in melanoma.

    Oskar Marin-Bejar;Aljosja Rogiers;Michael Dewaele;Julia Femel

  • LEDGINs, non-catalytic site inhibitors of HIV-1 integrase: a patent review (2006 - 2014).

    Jonas Demeulemeester;Patrick Chaltin;Arnaud Marchand;Marc De Maeyer

  • Retroviral integration: Site matters: Mechanisms and consequences of retroviral integration site selection.

    Jonas Demeulemeester;Jan De Rijck;Rik Gijsbers;Zeger Debyser

  • Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors.

    Jiqiu Cheng;Jiqiu Cheng;Jonas Demeulemeester;Jonas Demeulemeester;David C. Wedge;David C. Wedge;Hans Kristian Moen Vollan;Hans Kristian Moen Vollan

  • Neutral tumor evolution

    Maxime Tarabichi;Maxime Tarabichi;Iñigo Martincorena;Moritz Gerstung;Armand M. Leroi

  • Tracing the origin of disseminated tumor cells in breast cancer using single-cell sequencing.

    Jonas Demeulemeester;Jonas Demeulemeester;Parveen Kumar;Parveen Kumar;Elen K. Møller;Silje Nord

  • Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes

    Stefan C. Dentro;Stefan C. Dentro;Stefan C. Dentro;Ignaty Leshchiner;Kerstin Haase;Maxime Tarabichi;Maxime Tarabichi

Frequent Co-Authors

Zeger Debyser
Zeger Debyser KU Leuven
Peter Van Loo
Peter Van Loo The Francis Crick Institute
Frauke Christ
Frauke Christ KU Leuven
Rik Gijsbers
Rik Gijsbers KU Leuven
David C. Wedge
David C. Wedge University of Manchester
Peter J. Campbell
Peter J. Campbell Wellcome Sanger Institute
Paul C. Boutros
Paul C. Boutros University of California, Los Angeles
Rameen Beroukhim
Rameen Beroukhim Harvard University
Moritz Gerstung
Moritz Gerstung German Cancer Research Center
Gad Getz
Gad Getz Broad Institute

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