What is he best known for?
The fields of study he is best known for:
His scientific interests lie mostly in Biochemistry, Cell biology, Epidermal growth factor, Biophysics and Embryonic stem cell.
His Cell biology study combines topics from a wide range of disciplines, such as Cellular differentiation and Stress fiber, Cytoskeleton.
His biological study spans a wide range of topics, including Endocrinology and Membrane potential.
The various areas that Leon G.J. Tertoolen examines in his Biophysics study include Cytoplasm, Yellow fluorescent protein, Transmembrane protein, Protein kinase C and Intracellular.
The Embryonic stem cell study combines topics in areas such as Myocyte, Myocardial infarction, Stem cell and Pharmacology.
As a part of the same scientific family, Leon G.J. Tertoolen mostly works in the field of Myocyte, focusing on Cell and, on occasion, Extracellular.
His most cited work include:
- Differentiation of human embryonic stem cells to cardiomyocytes (1113 citations)
- FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2(SIRT1). (474 citations)
- Phorbol ester and diacylglycerol mimic growth factors in raising cytoplasmic pH. (394 citations)
What are the main themes of his work throughout his whole career to date?
Cell biology, Biophysics, Biochemistry, Induced pluripotent stem cell and Embryonic stem cell are his primary areas of study.
The study incorporates disciplines such as Receptor and Epidermal growth factor in addition to Cell biology.
He focuses mostly in the field of Epidermal growth factor, narrowing it down to matters related to Extracellular and, in some cases, Cell culture and Ion transporter.
Leon G.J. Tertoolen usually deals with Biophysics and limits it to topics linked to Membrane and Polarity and Xenopus.
His work on Fluorescence recovery after photobleaching and Phospholipase C as part of general Biochemistry study is frequently connected to Fusion protein and Histamine H1 receptor, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them.
His Embryonic stem cell research incorporates elements of Immunology, Stem cell, Myocyte, Patch clamp and Pharmacology.
He most often published in these fields:
- Cell biology (41.35%)
- Biophysics (22.12%)
- Biochemistry (21.15%)
What were the highlights of his more recent work (between 2014-2020)?
- Induced pluripotent stem cell (20.19%)
- Cell biology (41.35%)
- Contractility (7.69%)
In recent papers he was focusing on the following fields of study:
Leon G.J. Tertoolen mainly investigates Induced pluripotent stem cell, Cell biology, Contractility, Contraction and In vitro.
His Induced pluripotent stem cell research is classified as research in Embryonic stem cell.
His studies deal with areas such as Endothelium and Cell type as well as Embryonic stem cell.
Leon G.J. Tertoolen combines subjects such as Gene expression, Human myocardium and Cell–cell interaction with his study of Cell biology.
The concepts of his Contractility study are interwoven with issues in Stromal cell, Cellular differentiation, Cardiomyopathy, Intracellular and Drug.
His Contraction research integrates issues from Myocyte, Inotrope, Cardiology and Biophysics.
Between 2014 and 2020, his most popular works were:
- Functional maturation of human pluripotent stem cell derived cardiomyocytes in vitro--correlation between contraction force and electrophysiology. (131 citations)
- Small molecule absorption by PDMS in the context of drug response bioassays (130 citations)
- Three-dimensional cardiac microtissues composed of cardiomyocytes and endothelial cells co-differentiated from human pluripotent stem cells. (124 citations)
In his most recent research, the most cited papers focused on:
His primary areas of investigation include Induced pluripotent stem cell, Cell biology, Stem cell, Gene expression and Contraction.
His research integrates issues of Endothelium, Biophysical Phenomena, Cell type and Anatomy in his study of Induced pluripotent stem cell.
His Cell biology research is multidisciplinary, relying on both Stromal cell, Cellular differentiation and Cardiomyopathy.
His Stem cell research is multidisciplinary, incorporating perspectives in Computational biology, Human heart, Disease and Safety pharmacology.
His research in Gene expression intersects with topics in Sarcomere organization, Downregulation and upregulation and Cell morphology.
His Contraction research also works with subjects such as
- Biomedical engineering which intersects with area such as Patch clamp, In vivo, Cardiac cycle, Electrophysiology and Phenotype,
- In vitro which is related to area like Membrane potential and Drug discovery.
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