What is he best known for?
The fields of study he is best known for:
His scientific interests lie mostly in Protein tyrosine phosphatase, Biochemistry, Phosphatase, Cell biology and Signal transduction.
His biological study spans a wide range of topics, including Dephosphorylation, Receptor tyrosine kinase, Differential expression, Autophosphorylation and Subcellular localization.
In the subject of general Biochemistry, his work in Phosphorylation, Peptide and Stable isotope labeling by amino acids in cell culture is often linked to Leukotriene C4, thereby combining diverse domains of study.
Jeroen den Hertog combines subjects such as Protein structure, Biophysics, Activator and Proteolysis with his study of Phosphatase.
His research in Cell biology intersects with topics in Genetics and Lipoxygenase.
Immunology, Bone development, Synaptogenesis, Disease and Bone morphogenesis is closely connected to Mutation in his research, which is encompassed under the umbrella topic of Signal transduction.
His most cited work include:
- Dimerization inhibits the activity of receptor-like protein-tyrosine phosphatase-|[alpha]| (171 citations)
- Laminin-α4 and Integrin-Linked Kinase Mutations Cause Human Cardiomyopathy Via Simultaneous Defects in Cardiomyocytes and Endothelial Cells (170 citations)
- Epidermal growth factor activates calcium channels by phospholipase A25-lipoxygenase-mediated leukotriene C4 production (163 citations)
What are the main themes of his work throughout his whole career to date?
Jeroen den Hertog mainly investigates Cell biology, Protein tyrosine phosphatase, Zebrafish, Phosphatase and Molecular biology.
His Cell biology research is multidisciplinary, incorporating elements of Receptor, In vitro and Embryonic stem cell, Gene.
His Protein tyrosine phosphatase study is within the categories of Biochemistry, Phosphorylation, Signal transduction and Tyrosine.
His studies in Phosphorylation integrate themes in fields like Kinase and Peptide.
His Zebrafish study incorporates themes from Mutation, Protein kinase B, Regeneration and PTEN.
His studies deal with areas such as Mutant, Ectodomain, Peptide sequence, Protein structure and Allosteric regulation as well as Phosphatase.
He most often published in these fields:
- Cell biology (64.91%)
- Protein tyrosine phosphatase (61.40%)
- Zebrafish (50.88%)
What were the highlights of his more recent work (between 2013-2021)?
- Zebrafish (50.88%)
- Cell biology (64.91%)
- PTEN (26.32%)
In recent papers he was focusing on the following fields of study:
Zebrafish, Cell biology, PTEN, Protein tyrosine phosphatase and Phosphatase are his primary areas of study.
His Zebrafish study incorporates themes from Mutation, Molecular biology and Protein kinase B.
His Cell biology research incorporates elements of Embryonic stem cell, Small molecule and Target protein.
Signal transduction, Phosphorylation and Biochemistry are inextricably linked to his Protein tyrosine phosphatase research.
The study incorporates disciplines such as Tyrosine and Phosphoproteomics in addition to Signal transduction.
His Biochemistry research includes elements of Function and Resorption.
Between 2013 and 2021, his most popular works were:
- Comparative interactomics analysis of different ALS-associated proteins identifies converging molecular pathways (68 citations)
- Heterozygous germline mutations in A2ML1 are associated with a disorder clinically related to Noonan syndrome (43 citations)
- A unified nomenclature and amino acid numbering for human PTEN. (40 citations)
In his most recent research, the most cited papers focused on:
His main research concerns Protein tyrosine phosphatase, Cell biology, Stem cell, Signal transduction and Cancer research.
His Protein tyrosine phosphatase study necessitates a more in-depth grasp of Phosphorylation.
His Phosphorylation study contributes to a more complete understanding of Biochemistry.
The various areas that Jeroen den Hertog examines in his Cell biology study include Genetics and Zebrafish.
Jeroen den Hertog interconnects Mutation and Noonan syndrome in the investigation of issues within Signal transduction.
Jeroen den Hertog has included themes like PTEN, Phosphatase and Oncogenicity, Gene, Germline in his Cancer research study.
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