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Biology and Biochemistry

D-Index
55
Citations
11022
World Ranking
15041
National Ranking
365

Overview

Jeroen Bakkers is affiliated with Utrecht University in the Netherlands and has a research focus spanning biochemistry, genetics, molecular biology, and medicine. Their work emphasizes molecular biology and cardiology, along with related subfields such as epidemiology, cell biology, and genetics.

The scientist's main topics of research include:

  • Congenital heart defects research
  • Congenital Heart Disease Studies
  • Cardiomyopathy and Myosin Studies
  • RNA modifications and cancer
  • Zebrafish Biomedical Research Applications
  • Genomics and Chromatin Dynamics
  • Developmental Biology and Gene Regulation

Bakkers has contributed to numerous scientific publications, appearing frequently in prominent venues such as bioRxiv (Cold Spring Harbor Laboratory), with 9 publications, and other journals including Nature Cardiovascular Research (3 publications), Development (3 publications), Nature (2 publications), and Circulation Research (2 publications).

Recent research papers include:

  • "Macrophages provide a transient muscle stem cell niche via NAMPT secretion," 2021, Nature
  • "Single-cell profiling of transcriptome and histone modifications with EpiDamID," 2022, Molecular Cell
  • "Genome-Wide Analysis Identifies an Essential Human TBX3 Pacemaker Enhancer," 2020, Circulation Research
  • "Prrx1b restricts fibrosis and promotes Nrg1-dependent cardiomyocyte proliferation during zebrafish heart regeneration," 2021, Development
  • "T-box transcription factor 3 governs a transcriptional program for the function of the mouse atrioventricular conduction system," 2020, Proceedings of the National Academy of Sciences

Jeroen Bakkers collaborates frequently with other researchers, with notable coauthors including Phong D. Nguyen, Federico Tessadori, Vincent M. Christoffels, Dennis E. M. de Bakker, and Sarah M. Kamel, with collaboration counts ranging from 7 to 13 joint publications for each.

Best Publications

  • Zebrafish as a model to study cardiac development and human cardiac disease

    Jeroen Bakkers

  • Galectin-1 is essential in tumor angiogenesis and is a target for antiangiogenesis therapy

    Victor L. J. L. Thijssen;Ruben Postel;Ricardo J. M. G. E. Brandwijk;Ruud P. M. Dings

  • Essential role of BCL9-2 in the switch between β-catenin's adhesive and transcriptional functions

    Felix H. Brembeck;Thomas Schwarz-Romond;Jeroen Bakkers;Sabine Wilhelm

  • Distinct phases of cardiomyocyte differentiation regulate growth of the zebrafish heart.

    Emma de Pater;Linda Clijsters;Sara R. Marques;Sara R. Marques;Yi-Fan Lin

  • Genome-wide RNA Tomography in the Zebrafish Embryo

    Jan Philipp Junker;Emily S Noël;Victor Guryev;Kevin A Peterson

  • Metastatic behaviour of primary human tumours in a zebrafish xenotransplantation model.

    Ines J Marques;Frank Ulrich Weiss;Danielle H Vlecken;Claudia Nitsche

  • MUSCLEMOTION: A Versatile Open Software Tool to Quantify Cardiomyocyte and Cardiac Muscle Contraction In Vitro and In Vivo.

    Luca Sala;Berend J. Van Meer;Leon G.J. Tertoolen;Jeroen Bakkers

  • Zebrafish ΔNp63 Is a Direct Target of Bmp Signaling and Encodes a Transcriptional Repressor Blocking Neural Specification in the Ventral Ectoderm

    Jeroen Bakkers;Marc Hild;Carina Kramer;Makoto Furutani-Seiki

  • Laminin-α4 and Integrin-Linked Kinase Mutations Cause Human Cardiomyopathy Via Simultaneous Defects in Cardiomyocytes and Endothelial Cells

    Ralph Knöll;Ruben Postel;Jianming Wang;Ralph Krätzner

  • The ankyrin repeat protein Diversin recruits Casein kinase Iε to the β-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signaling

    Thomas Schwarz-Romond;Christian Asbrand;Jeroen Bakkers;Michael Kühl

  • Ubiad1 Is an Antioxidant Enzyme that Regulates eNOS Activity by CoQ10 Synthesis

    Vera Mugoni;Ruben Postel;Valeria Catanzaro;Elisa De Luca

  • Genetic variation in T-box binding element functionally affects SCN5A/SCN10A enhancer

    Malou van den Boogaard;L.Y. Elaine Wong;Federico Tessadori;Martijn L. Bakker

  • Single-cell analysis uncovers that metabolic reprogramming by ErbB2 signaling is essential for cardiomyocyte proliferation in the regenerating heart

    Hessel Honkoop;Dennis Em de Bakker;Alla Aharonov;Fabian Kruse

  • Identification and functional characterization of cardiac pacemaker cells in zebrafish.

    Federico Tessadori;Jan Hendrik van Weerd;Silja B. Burkhard;Arie O. Verkerk

  • Zebrafish Bmp4 regulates left-right asymmetry at two distinct developmental time points.

    Sonja Chocron;Manon C. Verhoeven;Fabian Rentzsch;Matthias Hammerschmidt

  • Spatially Resolved Genome-wide Transcriptional Profiling Identifies BMP Signaling as Essential Regulator of Zebrafish Cardiomyocyte Regeneration

    Chi Chung Wu;Fabian Kruse;Mohankrishna Dalvoy Vasudevarao;Jan Philipp Junker

  • Early endocardial morphogenesis requires Scl/Tal1.

    Jeroen Bussmann;Jeroen Bakkers;Stefan Schulte-Merker

  • Has2 is required upstream of Rac1 to govern dorsal migration of lateral cells during zebrafish gastrulation.

    Jeroen Bakkers;Carina Kramer;Joris Pothof;Nicolette E. M. Quaedvlieg

  • The Bmp Gradient of the Zebrafish Gastrula Guides Migrating Lateral Cells by Regulating Cell-Cell Adhesion

    Sophia von der Hardt;Jeroen Bakkers;Adi Inbal;Lara Carvalho

  • Rotation and Asymmetric Development of the Zebrafish Heart Requires Directed Migration of Cardiac Progenitor Cells

    Kelly A. Smith;Sonja Chocron;Sophia von der Hardt;Emma de Pater

Frequent Co-Authors

Vincent M. Christoffels
Vincent M. Christoffels University of Amsterdam
Matthias Hammerschmidt
Matthias Hammerschmidt University of Cologne
Herman P. Spaink
Herman P. Spaink Leiden University
Jeroen den Hertog
Jeroen den Hertog Hubrecht Institute for Developmental Biology and Stem Cell Research
Benjamin M. Hogan
Benjamin M. Hogan University of Melbourne
Alexander van Oudenaarden
Alexander van Oudenaarden University Medical Center Utrecht
Gilbert Weidinger
Gilbert Weidinger University of Ulm
Christine L. Mummery
Christine L. Mummery Leiden University Medical Center
Eugene Berezikov
Eugene Berezikov University Medical Center Groningen
Peter D. Currie
Peter D. Currie Monash University

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