Fumio Arai

Overview

Best Publications

• Tie2/Angiopoietin-1 Signaling Regulates Hematopoietic Stem Cell Quiescence in the Bone Marrow Niche

  Fumio Arai;Atsushi Hirao;Masako Ohmura;Hidetaka Sato

  2460
  Citations

• Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells.

  Keisuke Ito;Atsushi Hirao;Atsushi Hirao;Fumio Arai;Keiyo Takubo

  1514
  Citations

• Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells

  Keisuke Ito;Atsushi Hirao;Fumio Arai;Sahoko Matsuoka

  1381
  Citations

• Foxo3a is essential for maintenance of the hematopoietic stem cell pool.

  Kana Miyamoto;Kiyomi Y. Araki;Kazuhito Naka;Fumio Arai

  977
  Citations

• Thrombopoietin/MPL Signaling Regulates Hematopoietic Stem Cell Quiescence and Interaction with the Osteoblastic Niche

  Hiroki Yoshihara;Fumio Arai;Kentaro Hosokawa;Tetsuya Hagiwara

  922
  Citations

• Commitment and Differentiation of Osteoclast Precursor Cells by the Sequential Expression of C-Fms and Receptor Activator of Nuclear Factor κb (Rank) Receptors

  Fumio Arai;Takeshi Miyamoto;Osamu Ohneda;Tornohisa Inada

  827
  Citations

• A PML–PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance.

  Keisuke Ito;Arkaitz Carracedo;Dror Weiss;Fumio Arai

  713
  Citations

• Interferon regulatory factor-2 protects quiescent hematopoietic stem cells from type I interferon― dependent exhaustion

  Taku Sato;Nobuyuki Onai;Hiroki Yoshihara;Fumio Arai

  487
  Citations

• Bifurcation of osteoclasts and dendritic cells from common progenitors.

  Takeshi Miyamoto;Osamu Ohneda;Fumio Arai;Katsuya Iwamoto

  397
  Citations

• Maintenance of quiescent hematopoietic stem cells in the osteoblastic niche.

  Fumio Arai;Toshio Suda

  345
  Citations

• Noncanonical Wnt Signaling Maintains Hematopoietic Stem Cells in the Niche

  Ryohichi Sugimura;Xi C. He;Aparna Venkatraman;Aparna Venkatraman;Fumio Arai

  324
  Citations

• Mesenchymal stem cells in perichondrium express activated leukocyte cell adhesion molecule and participate in bone marrow formation

  Fumio Arai;Osamu Ohneda;Takeshi Miyamoto;Takeshi Miyamoto;Xiu Qin Zhang

  309
  Citations

• Isolation and characterization of endosteal niche cell populations that regulate hematopoietic stem cells

  Yuka Nakamura;Fumio Arai;Hiroko Iwasaki;Kentaro Hosokawa

  292
  Citations

• Hematopoietic stem cells and their niche.

  Toshio Suda;Fumio Arai;Atsushi Hirao

  291
  Citations

• Self-renewal of a purified Tie2+ hematopoietic stem cell population relies on mitochondrial clearance.

  Kyoko Ito;Raphaël Turcotte;Jinhua Cui;Samuel E. Zimmerman

  291
  Citations

• Stem Cell Differentiation as a Non-Markov Stochastic Process.

  Patrick S. Stumpf;Rosanna C.G. Smith;Michael Lenz;Michael Lenz;Andreas Schuppert

  227
  Citations

• Fbxw7 acts as a critical fail-safe against premature loss of hematopoietic stem cells and development of T-ALL

  Sahoko Matsuoka;Yuichi Oike;Yuichi Oike;Ichiro Onoyama;Atsushi Iwama

  211
  Citations

• ALCAM (CD166): its role in hematopoietic and endothelial development.

  Osamu Ohneda;Osamu Ohneda;Osamu Ohneda;Kinuko Ohneda;Kinuko Ohneda;Kinuko Ohneda;Fumio Arai;Fumio Arai;Fumio Arai;James Lee;James Lee;James Lee

  203
  Citations

• Function of oxidative stress in the regulation of hematopoietic stem cell-niche interaction

  Kentaro Hosokawa;Fumio Arai;Hiroki Yoshihara;Yuka Nakamura

  169
  Citations

• A PML–PPAR-δ Pathway for Fatty Acid Oxidation Regulates Hematopoietic Stem Cell Maintenance Through the Control of Asymmetric Division.

  Keisuke Ito;Arkaitz Carracedo;Fumio Arai;Ugo Ala

  26
  Citations