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Chemistry

D-Index
70
Citations
15403
World Ranking
5956
National Ranking
144

Research.com Recognitions

  • 2007 - Fellow of the Australian Academy of Science

Overview

Peter A. Lay is affiliated with the University of Sydney in Australia and has contributed extensively to the fields of chemistry and materials science. Their work spans multiple subfields, including materials chemistry, inorganic chemistry, oncology, molecular biology, and nutrition and dietetics.

The research focus of Peter A. Lay includes crystallization and solubility studies, X-ray diffraction in crystallography, synthesis and properties of metal complexes, vanadium and halogenation chemistry, metal-catalyzed oxygenation mechanisms, trace elements in health, and extracellular vesicles in disease.

Frequent co-authors in their publications include Aviva Levina, Liam J. Stephens, Melissa V. Werrett, Philip C. Andrews, and Debbie C. Crans.

Peter A. Lay has published extensively in notable venues. The Cambridge Structural Database features prominently among their publication venues with 18 contributions. Other frequent venues include Inorganic Chemistry, Chemistry - A European Journal, Angewandte Chemie, and Angewandte Chemie International Edition.

Notable recent papers authored by Peter A. Lay include:

  • A Short-Lived but Highly Cytotoxic Vanadium(V) Complex as a Potential Drug Lead for Brain Cancer Treatment by Intratumoral Injections, 2020, Angewandte Chemie International Edition
  • Vanadium(V/IV)-Transferrin Binding Disrupts the Transferrin Cycle and Reduces Vanadium Uptake and Antiproliferative Activity in Human Lung Cancer Cells, 2020, Inorganic Chemistry
  • Concentrations of toxic metals and essential trace elements vary among individual neurons in the human locus ceruleus, 2020, PLoS ONE
  • Advantageous Reactivity of Unstable Metal Complexes: Potential Applications of Metal-Based Anticancer Drugs for Intratumoral Injections, 2022, Pharmaceutics
  • Vanadium Chloro-Substituted Schiff Base Catecholate Complexes are Reducible, Lipophilic, Water Stable, and Have Anticancer Activities, 2022, Inorganic Chemistry

Peter A. Lay was recognized as a Fellow of the Australian Academy of Science in 2007.

Best Publications

  • The Decamethylferrocenium/Decamethylferrocene Redox Couple: A Superior Redox Standard to the Ferrocenium/Ferrocene Redox Couple for Studying Solvent Effects on the Thermodynamics of Electron Transfer

    Indra Noviandri;Kylie N. Brown;Douglas S. Fleming;Peter T. Gulyas

  • Recent developments in ruthenium anticancer drugs.

    Aviva Levina;Anannya Mitra;Peter A. Lay

  • Copper complexes of non-steroidal anti-inflammatory drugs: an opportunity yet to be realized

    Jane E. Weder;Carolyn T. Dillon;Trevor W. Hambley;Brendan J. Kennedy

  • Studies on the genotoxicity of chromium: from the test tube to the cell

    Rachel Codd;Carolyn T Dillon;Aviva Levina;Peter A Lay

  • Mechanistic studies of relevance to the biological activities of chromium

    Aviva Levina;Peter A. Lay

  • Cis‐Bis(2,2′‐Bipyridine‐N,N′) Complexes of Ruthenium(III)/(II) and Osmium(III)/(II)

    Peter A. Lay;Alan M. Sargeson;Henry Taube;Mei H. Chou

  • Parkinson's disease-linked human PARK9/ATP13A2 maintains zinc homeostasis and promotes α-Synuclein externalization via exosomes

    Stephanie M.Y. Kong;Brian K.K. Chan;Jin-Sung Park;Kathryn J. Hill

  • Chemical properties and toxicity of chromium(III) nutritional supplements.

    Aviva Levina;Peter A. Lay

  • Syntheses and characterization of anti-inflammatory dinuclear and mononuclear zinc indomethacin complexes. Crystal structures of [Zn2(indomethacin)4(L)2] (L = N,N-dimethylacetamide, pyridine, 1-methyl-2-pyrrolidinone) and [Zn(indomethacin)2(L1)2] (L1 = ethanol, methanol).

    Zhou Q;Hambley Tw;Kennedy Bj;Lay Pa

  • Speciation of metal drugs, supplements and toxins in media and bodily fluids controls in vitro activities

    Aviva Levina;Debbie C. Crans;Peter A. Lay

  • Assessment tools for microplastics and natural fibres ingested by fish in an urbanised estuary.

    Jennifer E. Halstead;James A. Smith;Elizabeth A. Carter;Peter A. Lay

  • Chemical alterations to murine brain tissue induced by formalin fixation: implications for biospectroscopic imaging and mapping studies of disease pathogenesis

    Mark J Hackett;James A McQuillan;Fatima El-Assaad;Jade B Aitken

  • Molecular Mechanism of AHSP-Mediated Stabilization of α-Hemoglobin

    Liang Feng;David A. Gell;Suiping Zhou;Lichuan Gu

  • Chromium in Biology: Toxicology and Nutritional Aspects

    Peter A. Lay

  • Anti-Inflammatory Dinuclear Copper(II) Complexes with Indomethacin. Synthesis, Magnetism and EPR Spectroscopy. Crystal Structure of the N,N-Dimethylformamide Adduct.

    Jane E Weder;Trevor W Hambley;Brendan J Kennedy;Peter A Lay

  • Chromium(V)-induced cleavage of DNA: are chromium(V) complexes the active carcinogens in chromium(VI)-induced cancers?

    Rodney P. Farrell;Robert J. Judd;Peter A. Lay;Nicholas E. Dixon

  • X-ray-induced photo-chemistry and X-ray absorption spectroscopy of biological samples.

    Graham N. George;Ingrid J. Pickering;M. Jake Pushie;Kurt Nienaber

  • Solvent Effects on the Electronic Spectrum of C60

    Sean H. Gallagher;Robert S. Armstrong;Peter A. Lay;Christopher A. Reed

  • Metal-based anti-diabetic drugs: advances and challenges

    Aviva Levina;Peter A. Lay

  • Characterization of a Ruthenium(III)/NAMI‐A Adduct with Bovine Serum Albumin that Exhibits a High Anti‐Metastatic Activity

    Mimi Liu;Zhi Jun Lim;Yee Yen Gwee;Aviva Levina

  • Activation of Molecular Oxygen during the Reactions of Chromium(VI/V/IV) with Biological Reductants: Implications for Chromium-Induced Genotoxicities1

    Peter A. Lay;Aviva Levina

Frequent Co-Authors

Trevor W. Hambley
Trevor W. Hambley University of Sydney
Alan M. Sargeson
Alan M. Sargeson Australian National University
Henry Taube
Henry Taube Stanford University
Geoffrey A. Lawrance
Geoffrey A. Lawrance University of Newcastle Australia
Hugh H. Harris
Hugh H. Harris University of Adelaide
Brendan J. Kennedy
Brendan J. Kennedy University of Sydney
Nicholas E. Dixon
Nicholas E. Dixon University of Wollongong
Stefan Vogt
Stefan Vogt Argonne National Laboratory
Paul K. Witting
Paul K. Witting University of Sydney
Christopher A. Reed
Christopher A. Reed University of California, Riverside

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