World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
87
Citations
25777
World Ranking
2849
National Ranking
1462

Chemistry

D-Index
85
Citations
24776
World Ranking
2684
National Ranking
927

Sidney M. Hecht publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where Sidney M. Hecht sits on this spectrum.

61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61 publications 1,295+

This scientist: 515 publications — 89th percentile

89% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

Sidney M. Hecht D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Sidney M. Hecht sits on this spectrum.

40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40 D-Index 159+

This scientist: 85 D-Index — 85th percentile

85% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

Research.com Recognitions

  • 2020 - Fellow, National Academy of Inventors
  • 2003 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1977 - Fellow of John Simon Guggenheim Memorial Foundation
  • 1975 - Fellow of Alfred P. Sloan Foundation

Overview

Sidney M. Hecht is affiliated with Arizona State University in the United States. Their research portfolio primarily spans the field of Biochemistry, Genetics, and Molecular Biology with a total of 37 publications. Within this main area, their work focuses on several subfields including Molecular Biology, Materials Chemistry, Oncology, Genetics, and Cancer Research.

The scientist's research topics include RNA and protein synthesis mechanisms, bacterial genetics and biotechnology, RNA modifications and cancer, DNA repair mechanisms, DNA and nucleic acid chemistry, glycosylation and glycoproteins research, and chemical synthesis and analysis.

Several recent papers authored or co-authored by Sidney M. Hecht demonstrate the breadth of their research. These include:

  • Interlocking activities of DNA polymerase β in the base excision repair pathway, 2022, Proceedings of the National Academy of Sciences
  • Antiferroptotic Activity of Phenothiazine Analogues: A Novel Therapeutic Strategy for Oxidative Stress Related Disease, 2020, ACS Medicinal Chemistry Letters
  • Expansion of the Genetic Code Through the Use of Modified Bacterial Ribosomes, 2021, Journal of Molecular Biology
  • Elongation Factor P Modulates the Incorporation of Structurally Diverse Noncanonical Amino Acids into Escherichia coli Dihydrofolate Reductase, 2023, Journal of the American Chemical Society
  • Protein synthesis with conformationally constrained cyclic dipeptides, 2020, Bioorganic & Medicinal Chemistry

Their collaboration network includes frequent co-authors such as Larisa M. Dedkova, Shengxi Chen, Sasha M. Daskalova, Omar M. Khdour, and Xiaoguang Bai. These partnerships underscore interdisciplinary approaches within their work.

Sidney M. Hecht has contributed to multiple publications in notable venues including Bioorganic & Medicinal Chemistry, ACS Chemical Biology, Biochemistry, The Cambridge Structural Database, and Proceedings of the National Academy of Sciences.

Recognition for this scientist's contributions has come in the form of prestigious fellowships. They have been named a Fellow of the National Academy of Inventors, a Fellow of the American Association for the Advancement of Science (AAAS), a Fellow of the John Simon Guggenheim Memorial Foundation, and a Fellow of the Alfred P. Sloan Foundation.

Best Publications

  • Oligonucleotide n-alkylphosphoramidates

    Sidney M. C O John W. Mallett Hecht

  • On the mechanism of topoisomerase I inhibition by camptothecin: evidence for binding to an enzyme-DNA complex

    Robert P. Hertzberg;Mary Jo Caranfa;Sidney M. Hecht

  • Synthesis of water-soluble (aminoalkyl)camptothecin analogues: inhibition of topoisomerase I and antitumor activity.

    William D. Kingsbury;Jeffrey C. Boehm;Dalia R. Jakas;Kenneth G. Holden

  • Bleomycin: new perspectives on the mechanism of action.

    Sidney M. Hecht

  • Camptothecin: current perspectives.

    Craig J. Thomas;Nicolas J. Rahier;Sidney M. Hecht

  • gamma Ray induced deoxyribonucleic acid strand breaks. 3' Glycolate termini.

    W D Henner;L O Rodriguez;S M Hecht;W A Haseltine

  • Eukaryotic mRNA cap binding protein: purification by affinity chromatography on sepharose-coupled m7GDP

    Nahum Sonenberg;Kathleen M. Rupprecht;Sidney M. Hecht;Aaron J. Shatkin

  • Identification of the First Specific Inhibitor of p90 Ribosomal S6 Kinase (RSK) Reveals an Unexpected Role for RSK in Cancer Cell Proliferation

    Jeffrey A. Smith;Celeste E. Poteet-Smith;Yaming Xu;Timothy M. Errington

  • Luotonin A. A Naturally Occurring Human DNA Topoisomerase I Poison

    Ali Cagir;Shannon H. Jones;Rong Gao;Brian M. Eisenhauer

  • The transcriptional complex between the BCL2 i-motif and hnRNP LL is a molecular switch for control of gene expression that can be modulated by small molecules.

    Hyun Jin Kang;Samantha Kendrick;Sidney M. Hecht;Laurence H. Hurley

  • Selective Tumor Cell Targeting by the Disaccharide Moiety of Bleomycin

    Zhiqiang Yu;Ryan M. Schmaltz;Trevor C. Bozeman;Rakesh Paul

  • T4 RNA ligase mediated preparation of novel "chemically misacylated" tRNAPheS.

    Thomas G. Heckler;Li Ho Chang;Yoshiyuki Zama;Takehiko Naka

  • The Dynamic Character of the BCL2 Promoter i-Motif Provides a Mechanism for Modulation of Gene Expression by Compounds That Bind Selectively to the Alternative DNA Hairpin Structure

    Samantha Kendrick;Hyun Jin Kang;Mohammad P. Alam;Manikandadas M. Madathil

  • Sequence Selective Cleavage of a DNA Octanucleotide by Chlorinated Bithiazoles and Bleomycins

    Guy Zuber;James C. Quada;Sidney M. Hecht

  • Enhanced D-amino acid incorporation into protein by modified ribosomes.

    Larisa M. Dedkova;Nour Eddine Fahmi;Serguei Y. Golovine;Sidney M. Hecht

  • Mitochondrial Nitroreductase Activity Enables Selective Imaging and Therapeutic Targeting

    Arnaud Chevalier;Yanmin Zhang;Omar M. Khdour;Justin B. Kaye

  • Oligonucleotide N-alkylphosphoramidates: synthesis and binding to polynucleotides

    Alfred Jager;Mark J. Levy;Sidney M. Hecht

  • Copper-dependent cleavage of DNA by bleomycin

    Ehrenfeld Gm;Shipley Jb;Heimbrook Dc;Sugiyama H

  • Javaniside, a novel DNA cleavage agent from Alangium javanicum having an unusual oxindole skeleton

    Ji Ma;Sidney M. Hecht

  • RNA Degradation by Bleomycin, a Naturally Occurring Bioconjugate

    Sidney M. Hecht

Frequent Co-Authors

Nelson J. Leonard
Nelson J. Leonard University of Illinois at Urbana-Champaign
Folke Skoog
Folke Skoog University of Wisconsin–Madison
Hiroshi Sugiyama
Hiroshi Sugiyama Kyoto University
Craig J. Thomas
Craig J. Thomas National Institutes of Health
G. A. Van Der Marel
G. A. Van Der Marel Leiden University
Xiang Zhou
Xiang Zhou Wuhan University
Stewart Shuman
Stewart Shuman Memorial Sloan Kettering Cancer Center
Stephen J. Benkovic
Stephen J. Benkovic Pennsylvania State University
Jia Zhou
Jia Zhou The University of Texas Medical Branch at Galveston

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