World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
64
Citations
17744
World Ranking
7949
National Ranking
2309

Research.com Recognitions

  • 2016 - Fellow, National Academy of Inventors

Overview

Peter A. Crooks is affiliated with the University of Arkansas for Medical Sciences in the United States. Their research spans the fields of Biochemistry, Genetics, and Molecular Biology, as well as Medicine, with a focused concentration in Molecular Biology, Physiology, Cellular and Molecular Neuroscience, Pharmacology, and Cancer Research.

The scientist's work covers several main topics including DNA Repair Mechanisms, RNA modifications and cancer, Alzheimer's disease research and treatments, Neuroscience and Neuropharmacology Research, Computational Drug Discovery Methods, Cholinesterase and Neurodegenerative Diseases, and Nicotinic Acetylcholine Receptors Study.

Recent scientific publications by Peter A. Crooks include:

  • Structural modeling of GSK3β implicates the inactive (DFG-out) conformation as the target bound by TDZD analogs (2020), Scientific Reports
  • Design and Synthesis of Novel Hybrid 8-Hydroxy Quinoline-Indole Derivatives as Inhibitors of Aβ Self-Aggregation and Metal Chelation-Induced Aβ Aggregation (2020), Molecules
  • Biobanked Glioblastoma Patient-Derived Organoids as a Precision Medicine Model to Study Inhibition of Invasion (2021), International Journal of Molecular Sciences
  • Novel hydroxybenzylamine-deoxyvasicinone hybrids as anticholinesterase therapeutics for Alzheimer's disease (2021), Bioorganic & Medicinal Chemistry
  • Binding Modes and Selectivity of Cannabinoid 1 (CB1) and Cannabinoid 2 (CB2) Receptor Ligands (2020), ACS Chemical Neuroscience

Frequent publication venues for this researcher include:

  • Scientific Reports (2 publications)
  • Molecules (2 publications)
  • Bioorganic & Medicinal Chemistry (2 publications)
  • Frontiers in Pharmacology (2 publications)
  • International Journal of Molecular Sciences (1 publication)

Peter A. Crooks collaborates regularly with several co-authors, including:

  • Narsimha Reddy Penthala (12 joint publications)
  • Soma Shekar Dachavaram (6 joint publications)
  • Meenakshisundaram Balasubramaniam (4 joint publications)
  • Robert J. Shmookler Reis (4 joint publications)
  • Paul L. Prather (4 joint publications)

In recognition of contributions to their field, Peter A. Crooks was awarded the title of Fellow by the National Academy of Inventors in 2016.

Best Publications

  • Polynucleotide analogs containing sulfonate and sulfonamide internucleoside linkages

    Joseph A. Maddry;Robert C. Reynolds;John A. Secrist;John A. Montgomery

  • High performance liquid chromatographic analysis of the pharmacologically active quinones and related compounds in the oil of the black seed (Nigella sativa L.)

    Omar A. Ghosheh;Abdulghani A. Houdi;Peter A. Crooks

  • An orally bioavailable parthenolide analog selectively eradicates acute myelogenous leukemia stem and progenitor cells

    Monica L. Guzman;Randall M. Rossi;Sundar Neelakantan;Xiaojie Li

  • Means to achieve sustained release of synergistic drugs by conjugation

    Paul Ashton;Peter Anthony Crooks;Tadeusz Cynkowski;Grazyna Cynkowska

  • A novel mechanism of action and potential use for lobeline as a treatment for psychostimulant abuse.

    Linda P. Dwoskin;Peter A. Crooks

  • Molecular pathway for thymoquinone-induced cell-cycle arrest and apoptosis in neoplastic keratinocytes.

    Hala U Gali-Muhtasib;Wassim G Abou Kheir;Lynn A Kheir;Nadine Darwiche

  • Aminoparthenolides as novel anti-leukemic agents: Discovery of the NF-kappaB inhibitor, DMAPT (LC-1).

    Sundar Neelakantan;Shama Nasim;Monica L. Guzman;Craig T. Jordan

  • Targeting Aberrant Glutathione Metabolism to Eradicate Human Acute Myelogenous Leukemia Cells

    Shanshan Pei;Mohammad Minhajuddin;Kevin P. Callahan;Marlene Balys

  • A NADPH Oxidase–Dependent Redox Signaling Pathway Mediates the Selective Radiosensitization Effect of Parthenolide in Prostate Cancer Cells

    Yulan Sun;Daret K. St. Clair;Yong Xu;Peter A. Crooks

  • Lobeline attenuates d-methamphetamine self-administration in rats.

    Steven B. Harrod;Linda P. Dwoskin;Peter A. Crooks;Jennifer E. Klebaur

  • Lobeline and nicotine evoke [3H]overflow from rat striatal slices preloaded with [3H]dopamine: differential inhibition of synaptosomal and vesicular [3H]dopamine uptake.

    Lihong Teng;Peter A. Crooks;Patricia K. Sonsalla;Linda P. Dwoskin

  • Competitive Neuronal Nicotinic Receptor Antagonists: A New Direction for Drug Discovery

    Linda P. Dwoskin;Peter A. Crooks

  • Unexpected pehnomenon in the high-performance liquid chromatographic anlaysis of racemic 14C-labelled nicotine: Separation of enantiomers in a totally achiral system

    K.C. Cundy;P.A. Crooks

  • Stereochemical course of the transmethylation catalyzed by catechol O-methyltransferase.

    R W Woodard;M D Tsai;H G Floss;P A Crooks

  • Vesicular monoamine transporter 2: role as a novel target for drug development.

    Guangrong Zheng;Linda P. Dwoskin;Peter A. Crooks

  • Cellulose sulfuric acid: An efficient biodegradable and recyclable solid acid catalyst for the one-pot synthesis of aryl-14H-dibenzo[a.j]xanthenes under solvent-free conditions

    J. Venu Madhav;Y. Thirupathi Reddy;P. Narsimha Reddy;M. Nikhil Reddy

  • Nornicotine is self-administered intravenously by rats

    M. T. Bardo;Thomas Green;P. A. Crooks;L. P. Dwoskin

  • (S)-(-)-Cotinine, the major brain metabolite of nicotine, stimulates nicotinic receptors to evoke [3H]dopamine release from rat striatal slices in a calcium-dependent manner.

    Linda P. Dwoskin;Lihong Teng;Susan T. Buxton;Peter A. Crooks

  • Lobeline Inhibits the Neurochemical and Behavioral Effects of Amphetamine

    Dennis K. Miller;Peter A. Crooks;Lihong Teng;Jeffrey M. Witkin

  • Contribution of CNS Nicotine Metabolites to the Neuropharmacological Effects of Nicotine and Tobacco Smoking

    Peter A. Crooks;Linda P. Dwoskin

  • Aminoparthenolides as Novel anti‐Leukemic Agents: Discovery of the NF‐ϰB Inhibitor, DMAPT (LC‐1).

    Sundar Neelakantan;Shama Nasim;Monica L. Guzman;Craig T. Jordan

Frequent Co-Authors

Linda P. Dwoskin
Linda P. Dwoskin University of Kentucky
Sean Parkin
Sean Parkin University of Kentucky
Michael T. Bardo
Michael T. Bardo University of Kentucky
Craig T. Jordan
Craig T. Jordan University of Colorado Anschutz Medical Campus
Michael L. Freeman
Michael L. Freeman Vanderbilt University Medical Center
Harikrishna Nakshatri
Harikrishna Nakshatri Indiana University
J. Michael McIntosh
J. Michael McIntosh University of Utah
Roger L. Papke
Roger L. Papke University of Florida
Chang-Guo Zhan
Chang-Guo Zhan University of Kentucky
Kimberly Nixon
Kimberly Nixon The University of Texas at Austin

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