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Julia Margaret Wendy Gee

Julia Margaret Wendy Gee

D-Index & Metrics

Biology and Biochemistry

D-Index
72
Citations
19068
World Ranking
6288
National Ranking
481

Overview

Julia Margaret Wendy Gee is affiliated with Cardiff University in the United Kingdom. Their research spans several fields of biochemistry, genetics, molecular biology, and medicine, with a focus on molecular biology, oncology, genetics, cancer research, and biomedical engineering.

Their work addresses key topics including epigenetics and DNA methylation, estrogen and related hormone effects, histone deacetylase inhibitors research, genomics and chromatin dynamics, cancer cells and metastasis, trace elements in health, and RNA research and splicing.

Significant recent publications by Julia Margaret Wendy Gee include:

  • Epigenetic reprogramming at estrogen-receptor binding sites alters 3D chromatin landscape in endocrine-resistant breast cancer, 2020, Nature Communications
  • The ZIP6/ZIP10 heteromer is essential for the zinc-mediated trigger of mitosis, 2020, Cellular and Molecular Life Sciences
  • The potential of epigenetic therapy to target the 3D epigenome in endocrine-resistant breast cancer, 2024, Nature Structural & Molecular Biology
  • Epigenome erosion and SOX10 drive neural crest phenotypic mimicry in triple-negative breast cancer, 2022, npj Breast Cancer
  • 4th generation nonsteroidal aromatase inhibitors: An iterative SAR-guided design, synthesis, and biological evaluation towards picomolar dual binding inhibitors, 2022, European Journal of Medicinal Chemistry

Their collaborations include frequent co-authorship with Joanna Achinger-Kawecka, C. Elizabeth Caldon, Shalima S. Nair, Qian Du, and Clare Stirzaker, each contributing jointly on multiple publications.

Julia Margaret Wendy Gee's research has been published in several venues, with repeated contributions to the Journal of the American Association for Laboratory Animal Science and bioRxiv (Cold Spring Harbor Laboratory). Other publications have appeared in Nature Communications, Cellular and Molecular Life Sciences, and Nature Structural & Molecular Biology.

Best Publications

  • EGFR and cancer prognosis

    Robert Ian Nicholson;Julia Margaret Wendy Gee;Maureen Elaine Harper

  • Elevated Levels of Epidermal Growth Factor Receptor/c-erbB2 Heterodimers Mediate an Autocrine Growth Regulatory Pathway in Tamoxifen-Resistant MCF-7 Cells

    Janice Mary Knowlden;Iain Robert Hutcheson;Helen E. Jones;Tracie-Ann Madden

  • Pharmacodynamic Studies of the Epidermal Growth Factor Receptor Inhibitor ZD1839 in Skin From Cancer Patients: Histopathologic and Molecular Consequences of Receptor Inhibition

    Joan Albanell;Federico Rojo;Steve Averbuch;Andrea Feyereislova

  • Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer.

    Suzanne A. Eccles;Eric O. Aboagye;Simak Ali;Annie S. Anderson

  • Phosphorylated Insulin-Like Growth Factor-I/Insulin Receptor Is Present in All Breast Cancer Subtypes and Is Related to Poor Survival

    Jennifer H. Law;Golareh Habibi;Kaiji Hu;Hamid Masoudi

  • Biologic and Clinical Characteristics of Breast Cancer With Single Hormone Receptor–Positive Phenotype

    Emad A. Rakha;Maysa E. El-Sayed;Andrew R. Green;E. Claire Paish

  • Insulin-like growth factor-I receptor signalling and acquired resistance to gefitinib (ZD1839; Iressa) in human breast and prostate cancer cells

    Helen E. Jones;Lindy Goddard;Julia Margaret Wendy Gee;Stephen Edward Hiscox

  • Epidermal growth factor receptor/HER2/insulin-like growth factor receptor signalling and oestrogen receptor activity in clinical breast cancer

    Julia Margaret Wendy Gee;J. F. Robertson;E. Gutteridge;I. O. Ellis

  • Enhanced epidermal growth factor receptor signaling in MCF7 breast cancer cells after long-term culture in the presence of the pure antiestrogen ICI 182,780 (Faslodex).

    Richard Andrew McClelland;Denise Barrow;Tracie-Ann Madden;Carol Mary Dutkowski

  • Phosphorylation of ERK1/2 mitogen-activated protein kinase is associated with poor response to anti-hormonal therapy and decreased patient survival in clinical breast cancer.

    Julia M.W. Gee;John F.R. Robertson;Ian O. Ellis;Robert I. Nicholson

  • Comparison of the short-term biological effects of 7alpha-[9-(4,4,5,5,5-pentafluoropentylsulfinyl)-nonyl]estra-1,3,5, (10)-triene-3,17beta-diol (Faslodex) versus tamoxifen in postmenopausal women with primary breast cancer.

    John F. Robertson;Robert I. Nicholson;Nigel J. Bundred;Elizabeth Anderson

  • Elevated Src activity promotes cellular invasion and motility in tamoxifen resistant breast cancer cells.

    Stephen Edward Hiscox;Liam David Morgan;Tim P. Green;Denise Barrow

  • Immunocytochemical localization of fos protein in human breast cancers and its relationship to a series of prognostic markers and response to endocrine therapy

    Julia M. W. Gee;Ian O. Ellis;John F. R. Robertson;Peter Willsher

  • Invasive lobular carcinoma of the breast: response to hormonal therapy and outcomes.

    Emad A. Rakha;Maysa E. El-Sayed;Desmond G. Powe;Andrew R. Green

  • Overexpression of cyclin D1 messenger RNA predicts for poor prognosis in estrogen receptor-positive breast cancer.

    Frances S. Kenny;Rina Hui;Elizabeth A. Musgrove;Julia M.W. Gee

  • Epidermal growth factor receptor expression in breast cancer: Association with response to endocrine therapy

    Robert Ian Nicholson;Richard Andrew McClelland;Julia Margaret Wendy Gee;David L. Manning

  • Insulin-like growth factor-I receptor signaling in tamoxifen-resistant breast cancer: A supporting role to the epidermal growth factor receptor

    Janice Mary Knowlden;Iain Robert Hutcheson;Denise Barrow;Julia Margaret Wendy Gee

  • Transferrin receptor (CD71) is a marker of poor prognosis in breast cancer and can predict response to tamoxifen.

    Hany Onsy Habashy;Hany Onsy Habashy;Desmond G. Powe;Cindy M. Staka;Emad A. Rakha

  • The antiepidermal growth factor receptor agent gefitinib (ZD1839/Iressa) improves antihormone response and prevents development of resistance in breast cancer in vitro.

    J. M. W. Gee;M. E. Harper;I. R. Hutcheson;T. A. Madden

  • Immunohistochemical determination of estrogen receptor-alpha phosphorylation in activation function AF1 in primary and tamoxifen-resistant breast cancer is indicative of a complex role for estrogen receptor-alpha phosphorylation in breast cancer progression [Abstract]

    S. Ali;N. Sarwar;J. Jiang;D. Peston

Frequent Co-Authors

Robert Ian Nicholson
Robert Ian Nicholson Cardiff University
Ian O. Ellis
Ian O. Ellis University of Nottingham
John F.R. Robertson
John F.R. Robertson University of Nottingham
Susan J. Clark
Susan J. Clark Garvan Institute of Medical Research
Elizabeth A. Musgrove
Elizabeth A. Musgrove University of Glasgow
Roger W. Blamey
Roger W. Blamey Nottingham City Hospital
Andrew R. Green
Andrew R. Green University of Nottingham
Robert Clarke
Robert Clarke University of Oxford
Emad A. Rakha
Emad A. Rakha University of Nottingham
Sarah E Pinder
Sarah E Pinder King's College London

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