World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
125
Citations
107268
World Ranking
308
National Ranking
162

Molecular Biology

D-Index
125
Citations
107268
World Ranking
220
National Ranking
134

Overview

X. Shirley Liu is affiliated with Harvard University in the United States and has contributed extensively to research in biochemistry, genetics, molecular biology, and medicine. Their work spans multiple subfields including molecular biology, oncology, immunology, cancer research, and pulmonary and respiratory medicine.

The scientist's research prominently focuses on cancer immunotherapy and biomarkers, single-cell and spatial transcriptomics, immune cell function and interaction, genomics and chromatin dynamics, cancer genomics and diagnostics, protein degradation and inhibitors, as well as RNA modifications and cancer.

Frequent publication venues for their work include bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Cancer Discovery, Cancer Immunology Research, and Cancer Research.

Among recent papers, notable titles and publication details include:

  • "TIMER2.0 for analysis of tumor-infiltrating immune cells," 2020, Nucleic Acids Research
  • "A single-cell and spatially resolved atlas of human breast cancers," 2021, Nature Genetics
  • "Large-scale public data reuse to model immunotherapy response and resistance," 2020, Genome Medicine
  • "Transfer learning enables predictions in network biology," 2023, Nature
  • "Stromal cell diversity associated with immune evasion in human triple-negative breast cancer," 2020, The EMBO Journal

X. Shirley Liu frequently collaborates with researchers including Myles Brown, Henry W. Long, Shengqing Gu, Clifford A. Meyer, and Zexian Zeng.

Best Publications

  • Model-based Analysis of ChIP-Seq (MACS)

    Yong Zhang;Tao Liu;Clifford A Meyer;Jérôme Eeckhoute

  • Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response

    Peng Jiang;Shengqing Gu;Deng Pan;Jingxin Fu

  • TIMER: A Web Server for Comprehensive Analysis of Tumor-Infiltrating Immune Cells

    Taiwen Li;Taiwen Li;Jingyu Fan;Binbin Wang;Nicole Traugh

  • TIMER2.0 for analysis of tumor-infiltrating immune cells

    Taiwen Li;Jingxin Fu;Jingxin Fu;Zexian Zeng;David Cohen

  • ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia

    Stephen G. Landt;Georgi K. Marinov;Anshul Kundaje;Pouya Kheradpour

  • MAGeCK enables robust identification of essential genes from genome-scale CRISPR/Cas9 knockout screens.

    Wei Li;Han Xu;Tengfei Xiao;Le Cong;Le Cong

  • Comprehensive analyses of tumor immunity: implications for cancer immunotherapy

    Bo Li;Eric Severson;Eric Severson;Jean Christophe Pignon;Haoquan Zhao

  • Identifying ChIP-seq enrichment using MACS

    Jianxing Feng;Tao Liu;Bo Qin;Yong Zhang

  • Genome-wide analysis of estrogen receptor binding sites

    Jason S Carroll;Clifford A Meyer;Jun Song;Wei Li

  • Chromosome-Wide Mapping of Estrogen Receptor Binding Reveals Long-Range Regulation Requiring the Forkhead Protein FoxA1

    Jason S. Carroll;X. Shirley Liu;Alexander S. Brodsky;Wei Li

  • Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2

    Myunggon Ko;Yun Huang;Yun Huang;Anna M. Jankowska;Utz J. Pape;Utz J. Pape

  • Integrative analysis of the Caenorhabditis elegans genome by the modENCODE project

    Mark B. Gerstein;Zhi John Lu;Eric L. Van Nostrand;Chao Cheng

  • FoxA1 Translates Epigenetic Signatures into Enhancer-Driven Lineage-Specific Transcription

    Mathieu Lupien;Jérôme Eeckhoute;Clifford A. Meyer;Qianben Wang

  • BioProspector: discovering conserved DNA motifs in upstream regulatory regions of co-expressed genes.

    X. Liu;Douglas L. Brutlag;Jun S. Liu

  • Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer

    Qianben Wang;Wei Li;Yong Zhang;Xin Yuan

  • The JAK2/STAT3 signaling pathway is required for growth of CD44+CD24– stem cell–like breast cancer cells in human tumors

    Lauren L.C. Marotta;Vanessa Almendro;Vanessa Almendro;Andriy Marusyk;Michail Shipitsin

  • Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells

    William A. Pastor;Utz J. Pape;Utz J. Pape;Yun Huang;Hope R. Henderson;Hope R. Henderson

  • A single-cell and spatially resolved atlas of human breast cancers.

    Sunny Z. Wu;Sunny Z. Wu;Ghamdan Al-Eryani;Ghamdan Al-Eryani;Daniel Lee Roden;Daniel Lee Roden;Simon Junankar;Simon Junankar

  • EZH2 Oncogenic Activity in Castration-Resistant Prostate Cancer Cells Is Polycomb-Independent

    Kexin Xu;Zhenhua Jeremy Wu;Anna C. Groner;Housheng Hansen He

  • PPARγ and C/EBP factors orchestrate adipocyte biology via adjacent binding on a genome-wide scale

    Martina I. Lefterova;Yong Zhang;David J. Steger;Michael Schupp

Frequent Co-Authors

Myles Brown
Myles Brown Harvard University
Jun S. Liu
Jun S. Liu Harvard University
Yong Zhang
Yong Zhang Tongji University
Henry W. Long
Henry W. Long Harvard University
Housheng Hansen He
Housheng Hansen He University of Toronto
Bo Li
Bo Li Hong Kong University of Science and Technology
Jason S. Carroll
Jason S. Carroll University of Cambridge
Kornelia Polyak
Kornelia Polyak Harvard University
Ramesh A. Shivdasani
Ramesh A. Shivdasani Harvard University
Kai W. Wucherpfennig
Kai W. Wucherpfennig Harvard University

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