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2025

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Rising Stars

D-Index
52
Citations
10427
World Ranking
269
National Ranking
46

Molecular Biology

D-Index
53
Citations
11994
World Ranking
2379
National Ranking
1177

Research.com Recognitions

  • 2025 - Research.com Rising Stars Award

Overview

Henry W. Long is affiliated with Harvard University in the United States, where their work primarily spans the disciplines of Biochemistry, Genetics, and Molecular Biology, with extensive contributions to Medicine. Their research focuses on several subfields including Molecular Biology, Pulmonary and Respiratory Medicine, Oncology, Cancer Research, and Immunology.

Long's main topics of study cover a range of areas related to cancer and genetics. These include Epigenetics and DNA Methylation, Prostate Cancer Treatment and Research, Cancer Genomics and Diagnostics, Genomics and Chromatin Dynamics, RNA modifications and cancer, Cancer Immunotherapy and Biomarkers, and Lung Cancer Research Studies.

Their recent notable publications include:

  • Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway, 2020, Cancer Cell
  • Prostate cancer reactivates developmental epigenomic programs during metastatic progression, 2020, Nature Genetics
  • Therapeutically Increasing MHC-I Expression Potentiates Immune Checkpoint Blockade, 2021, Cancer Discovery
  • EZH2 inhibition activates a dsRNA-STING-interferon stress axis that potentiates response to PD-1 checkpoint blockade in prostate cancer, 2021, Nature Cancer
  • Enhanced Efficacy of Simultaneous PD-1 and PD-L1 Immune Checkpoint Blockade in High-Grade Serous Ovarian Cancer, 2020, Cancer Research

Frequent co-authors who have collaborated extensively with Long include:

  • Paloma Cejas
  • Xintao Qiu
  • Myles Brown
  • Yingtian Xie
  • Matthew L. Freedman

Long's work has been regularly published in venues such as Cancer Research, bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Cancer Cell, and Nature Genetics. Their publication record shows a considerable focus on high-impact journals related to cancer and molecular biology research.

Best Publications

  • Rb1 and Trp53 cooperate to suppress prostate cancer lineage plasticity, metastasis, and antiandrogen resistance

    Sheng Yu Ku;Spencer Rosario;Yanqing Wang;Ping Mu

  • A major chromatin regulator determines resistance of tumor cells to T cell–mediated killing

    Deng Pan;Aya Kobayashi;Aya Kobayashi;Peng Jiang;Lucas Ferrari de Andrade

  • Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer

    Shaokun Shu;Charles Y. Lin;Housheng Hansen He;Robert M. Witwicki

  • The androgen receptor cistrome is extensively reprogrammed in human prostate tumorigenesis

    Mark M Pomerantz;Fugen Li;David Y Takeda;David Y Takeda;Romina Lenci

  • HIF1A Employs CDK8-Mediator to Stimulate RNAPII Elongation in Response to Hypoxia

    Matthew D. Galbraith;Mary A. Allen;Claire L. Bensard;Xiaoxing Wang;Xiaoxing Wang

  • Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway.

    Kari J. Kurppa;Yao Liu;Ciric To;Tinghu Zhang

  • The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice

    Elizabeth C. Townsend;Mark A. Murakami;Alexandra Christodoulou;Amanda L. Christie

  • A Somatically Acquired Enhancer of the Androgen Receptor Is a Noncoding Driver in Advanced Prostate Cancer

    David Y. Takeda;David Y. Takeda;Sándor Spisák;Ji Heui Seo;Connor Bell

  • Broadly permissive intestinal chromatin underlies lateral inhibition and cell plasticity

    Tae-Hee Kim;Fugen Li;Isabel Ferreiro-Neira;Isabel Ferreiro-Neira;Li-Lun Ho;Li-Lun Ho

  • Allele-Specific Chromatin Recruitment and Therapeutic Vulnerabilities of ESR1 Activating Mutations

    Rinath Jeselsohn;Rinath Jeselsohn;Johann S. Bergholz;Matthew Pun;MacIntosh Cornwell

  • Refined DNase-seq protocol and data analysis reveals intrinsic bias in transcription factor footprint identification

    Housheng Hansen He;Clifford A. Meyer;Sheng'En Shawn Hu;Sheng'En Shawn Hu;Mei Wei Chen

  • Prostate cancer reactivates developmental epigenomic programs during metastatic progression

    Mark M. Pomerantz;Xintao Qiu;Yanyun Zhu;David Y. Takeda;David Y. Takeda

  • VIPER: Visualization Pipeline for RNA-seq, a Snakemake workflow for efficient and complete RNA-seq analysis

    MacIntosh I. Cornwell;Mahesh Vangala;Len Taing;Zachary Herbert

  • Therapeutically Increasing MHC-I Expression Potentiates Immune Checkpoint Blockade.

    Shengqing Stan Gu;Wubing Zhang;Wubing Zhang;Xiaoqing Wang;Peng Jiang

  • EZH2 inhibition activates a dsRNA-STING-interferon stress axis that potentiates response to PD-1 checkpoint blockade in prostate cancer.

    Katherine L. Morel;Anjali V. Sheahan;Deborah L. Burkhart;Sylvan C. Baca

  • Regulation of the glucocorticoid receptor via a BET-dependent enhancer drives antiandrogen resistance in prostate cancer.

    Neel Shah;Ping Wang;John Wongvipat;Wouter R Karthaus

  • ARv7 Represses Tumor-Suppressor Genes in Castration-Resistant Prostate Cancer.

    Laura Cato;Jonas de Tribolet-Hardy;Jonas de Tribolet-Hardy;Irene Lee;Jaice T. Rottenberg

  • Enhancer signatures stratify and predict outcomes of non-functional pancreatic neuroendocrine tumors.

    Paloma Cejas;Yotam Drier;Yotam Drier;Yotam Drier;Koen M.A. Dreijerink;Lodewijk A.A. Brosens

  • Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer

    Shaokun Shu;Hua-Jun Wu;Jennifer Y. Ge;Jennifer Y. Ge;Rhamy Zeid

  • Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer

    Shaokun Shu;Charles Y. Lin;Housheng Hansen He;Robert M. Witwicki

Frequent Co-Authors

Myles Brown
Myles Brown Harvard University
Matthew L. Freedman
Matthew L. Freedman Harvard University
X. Shirley Liu
X. Shirley Liu Harvard University
William C. Hahn
William C. Hahn Dana-Farber Cancer Institute
Eliezer M. Van Allen
Eliezer M. Van Allen Harvard University
Kornelia Polyak
Kornelia Polyak Harvard University
Massimo Loda
Massimo Loda Cornell University
Ramesh A. Shivdasani
Ramesh A. Shivdasani Harvard University
Joaquim Bellmunt
Joaquim Bellmunt Beth Israel Deaconess Medical Center
Bradley E. Bernstein
Bradley E. Bernstein Broad Institute

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