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D-Index & Metrics

Genetics

D-Index
77
Citations
33606
World Ranking
1740
National Ranking
59

Research.com Recognitions

  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Bas van Steensel is affiliated with the Antoni van Leeuwenhoek Hospital in the Netherlands. Their research primarily focuses on biochemistry, genetics, and molecular biology, with a strong emphasis on molecular biology. Their work encompasses topics such as genomics and chromatin dynamics, RNA research and splicing, RNA and protein synthesis mechanisms, CRISPR and genetic engineering, chromosomal and genetic variations, DNA repair mechanisms, and nuclear structure and function.

The scientist has contributed to numerous publications across a variety of venues. Frequent publication sources include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Zenodo (CERN European Organization for Nuclear Research)
  • Nucleic Acids Research
  • eLife
  • Nature

Bas van Steensel has collaborated extensively with several co-authors, including:

  • Tom van Schaik
  • Stefano Giustino Manzo
  • Elzo de Wit
  • Christ Leemans
  • David M. Gilbert

Their recent papers illustrate the range and focus of their research, including:

  • "Nonlinear control of transcription through enhancer-promoter interactions," 2022, Nature
  • "3D genomics across the tree of life reveals condensin II as a determinant of architecture type," 2021, Science
  • "Impact of chromatin context on Cas9-induced DNA double-strand break repair pathway balance," 2021, Molecular Cell
  • "Cell cycle dynamics of lamina-associated DNA," 2020, EMBO Reports
  • "SPIN reveals genome-wide landscape of nuclear compartmentalization," 2021, Genome Biology

One recognized acknowledgment in their career is membership in the European Molecular Biology Organization (EMBO).

Best Publications

  • Easy quantitative assessment of genome editing by sequence trace decomposition

    Eva K. Brinkman;Tao Chen;Mario Amendola;Bas van Steensel

  • TRF2 Protects Human Telomeres from End-to-End Fusions

    Bas van Steensel;Agata Smogorzewska;Titia de Lange

  • Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions

    Lars Guelen;Ludo Pagie;Emilie Brasset;Wouter Meuleman;Wouter Meuleman

  • Nuclear organization of active and inactive chromatin domains uncovered by chromosome conformation capture–on-chip (4C)

    Marieke Simonis;Petra Klous;Erik Splinter;Yuri Moshkin

  • Molecular Maps of the Reorganization of Genome-Nuclear Lamina Interactions during Differentiation

    Daan Peric-Hupkes;Wouter Meuleman;Wouter Meuleman;Ludo Pagie;Sophia W.M. Bruggeman

  • Systematic Protein Location Mapping Reveals Five Principal Chromatin Types in Drosophila Cells

    Guillaume J. Filion;Joke G. van Bemmel;Ulrich Braunschweig;Wendy Talhout

  • Control of human telomere length by TRF1 and TRF2.

    Agata Smogorzewska;Bas van Steensel;Alessandro Bianchi;Stefan Oelmann

  • Lamina-Associated Domains: Links with Chromosome Architecture, Heterochromatin, and Gene Repression

    Bas van Steensel;Bas van Steensel;Andrew S. Belmont

  • A Human Telomeric Protein

    Laura Chong;Bas van Steensel;Dominique Broccoli;Hediye Erdjument-Bromage

  • Genome architecture: domain organization of interphase chromosomes

    Wendy A. Bickmore;Bas van Steensel

  • Single-Cell Dynamics of Genome-Nuclear Lamina Interactions

    Jop Kind;Ludo Pagie;Havva Ortabozkoyun;Shelagh Boyle

  • The Cohesin Release Factor WAPL Restricts Chromatin Loop Extension

    Judith H.I. Haarhuis;Robin H. van der Weide;Vincent A. Blomen;J. Omar Yáñez-Cuna

  • Characterization of the Drosophila melanogaster genome at the nuclear lamina

    Helen Pickersgill;Bernike Kalverda;Elzo de Wit;Wendy Talhout

  • Constitutive nuclear lamina–genome interactions are highly conserved and associated with A/T-rich sequence

    Wouter Meuleman;Daan Peric-Hupkes;Jop Kind;Jean-Bernard Beaudry

  • Genomic binding by the Drosophila Myc, Max, Mad/Mnt transcription factor network

    Amir Orian;Bas van Steensel;Jeffrey Delrow;Harmen J. Bussemaker

  • Genome-wide Maps of Nuclear Lamina Interactions in Single Human Cells

    Jop Kind;Jop Kind;Ludo Pagie;Sandra S. de Vries;Leila Nahidiazar

  • Genome-wide profiling of PRC1 and PRC2 Polycomb chromatin binding in Drosophila melanogaster.

    Bas Tolhuis;Inhua Muijrers;Elzo de Wit;Hans Teunissen

  • Prospero Acts as a Binary Switch between Self-Renewal and Differentiation in Drosophila Neural Stem Cells

    Semil P. Choksi;Tony D. Southall;Torsten Bossing;Karin Edoff

  • Detection of in vivo protein-DNA interactions using DamID in mammalian cells.

    Maartje J Vogel;Daniel Peric-Hupkes;Bas van Steensel

  • Genome-wide DNA replication profile for Drosophila melanogaster: a link between transcription and replication timing.

    Dirk Schübeler;David Scalzo;Charles Kooperberg;Bas van Steensel

Frequent Co-Authors

Elzo de Wit
Elzo de Wit Antoni van Leeuwenhoek Hospital
Harmen J. Bussemaker
Harmen J. Bussemaker Columbia University
Lodewyk F. A. Wessels
Lodewyk F. A. Wessels Antoni van Leeuwenhoek Hospital
Titia de Lange
Titia de Lange Rockefeller University
Maarten van Lohuizen
Maarten van Lohuizen Antoni van Leeuwenhoek Hospital
Andrew S. Belmont
Andrew S. Belmont University of Illinois at Urbana-Champaign
Wouter de Laat
Wouter de Laat Utrecht University
David M. Gilbert
David M. Gilbert Florida State University
Job Dekker
Job Dekker University of Massachusetts Chan Medical School
Steven Henikoff
Steven Henikoff Fred Hutchinson Cancer Research Center

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